Catalog No.
YHD40801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser42-Val150
Predicted molecular weight
39.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20674
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COX5A, Cytochrome c oxidase polypeptide Va, Cytochrome c oxidase subunit 5A, mitochondrial
UQCRB regulates mitochondrial energy metabolism by promoting COX5 A in atherosclerotic endothelial dysfunction., PMID:40445331
Prediction model of mitochondrial energy metabolism related genes in idiopathic pulmonary fibrosis and its correlation with immune microenvironment., PMID:40369105
Specific expression and common potential therapeutic drugs in different brain regions of major depressive disorder patients: bioinformatics analysis., PMID:40286923
Mendelian Randomization Reveals Potential Causal Relationships Between DNA Damage Repair-Related Genes and Inflammatory Bowel Disease., PMID:39857814
Bioinspired conductive oriented nanofiber felt with efficient ROS clearance and anti-inflammation for inducing M2 macrophage polarization and accelerating spinal cord injury repair., PMID:39760065
ZLN005 Reduces Neuroinflammation and Improves Mitochondrial Function in Mice with Perioperative Neurocognitive Disorders., PMID:39525311
Dynactin-1 mediates rescue of impaired axonal transport due to reduced mitochondrial bioenergetics in amyotrophic lateral sclerosis motor neurons., PMID:39440303
Profiling Reduced Expression of Contractile and Mitochondrial mRNAs in the Human Sinoatrial Node vs. Right Atrium and Predicting Their Suppressed Expression by Transcription Factors and/or microRNAs., PMID:39408732
Novel fungicide and neonicotinoid insecticide impair flight behavior in pollen foraging honey bees, Apis mellifera., PMID:39354118
Analysis of the prognostic value of mitochondria-related genes in patients with acute myocardial infarction., PMID:39103773
Investigation of copper-induced intestinal damage and proteome alterations in Takifugu rubripes: Potential health risks and environmental toxicology detection., PMID:39024957
Focused cancer pathway analysis revealed unique therapeutic targets in retinoblastoma., PMID:38834895
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells., PMID:38739449
Inhibition of DAPK3 Suppresses Radiation-Induced Cellular Senescence by Activation of a PGC1α-Dependent Metabolism Pathway in Brain Endothelial Cells., PMID:38563090
Hydrogen peroxide sensitivity connects the activity of COX5A and NPR3 to the regulation of YAP1 expression., PMID:38416461
TBX15 and SDHB expression changes in colorectal cancer serve as potential prognostic biomarkers., PMID:38378070
Mef2c regulates bone mass through Sost-dependent and -independent mechanisms., PMID:38042445
Tryptophan alleviates chronic heat stress-induced impairment of antioxidant capacities, inflammatory response, and mitochondrial function in broilers., PMID:38030895
Protein lysine acetylation played an important role in NH3-induced AEC2 damage and pulmonary fibrosis in piglets., PMID:37939958
COX5A as a potential biomarker for disease activity and organ damage in lupus., PMID:37891386
The long noncoding RNA lnc-H19 is important for endurance exercise by maintaining slow muscle fiber types., PMID:37742921
Lnc-Malat1 promotes slow myofiber-type transformation through sponging miR-129-5p in C2C12 myotubes., PMID:37634561
Mutations in Structural Genes of the Mitochondrial Complex IV May Influence Breast Cancer., PMID:37510369
Exploring biomarkers of premature ovarian insufficiency based on oxford nanopore transcriptional profile and machine learning., PMID:37460774
COX5A Alleviates Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress, Mitochondrial Dysfunction and Cardiomyocyte Apoptosis., PMID:37373547
Chronic fluoxetine treatment in socially-isolated rats modulates the prefrontal cortex synaptoproteome., PMID:37164273
Identification of cuproptosis-associated subtypes and signature genes for diagnosis and risk prediction of Ulcerative colitis based on machine learning., PMID:37090740
CLPP inhibition triggers apoptosis in human ovarian granulosa cells via COX5A abnormality-Mediated mitochondrial dysfunction., PMID:37007963
Ophiobolin A Covalently Targets Complex IV Leading to Mitochondrial Metabolic Collapse in Cancer Cells., PMID:36945520
Protective Role of Cytochrome C Oxidase 5A (COX5A) against Mitochondrial Disorder and Oxidative Stress in VSMC Phenotypic Modulation and Neointima Formation., PMID:36924093
Different Approaches for the Profiling of Cancer Pathway-Related Genes in Glioblastoma Cells., PMID:36142793
Identification of molecular signatures associated with sleep disorder and Alzheimer's disease., PMID:35990086
Cryo-EM structure of a monomeric yeast S. cerevisiae complex IV isolated with maltosides: Implications in supercomplex formation., PMID:35839926
Mitochondrial electron transport chain defects modify Parkinson's disease phenotypes in a Drosophila model., PMID:35764292
Effects of age on subcutaneous adipose tissue proteins in Chinese indigenous Ningxiang pig by TMT-labeled quantitative proteomics., PMID:35690344
A novel homozygous variant in COX5A causes an attenuated phenotype with failure to thrive, lactic acidosis, hypoglycemia, and short stature., PMID:35246835
The Ginsenoside Rg1 Rescues Mitochondrial Disorders in Aristolochic Acid-Induced Nephropathic Mice., PMID:34685389
Proteomic and electron microscopy study of myogenic differentiation of alveolar mucosa multipotent mesenchymal stromal cells in three-dimensional culture., PMID:34674377
Interactome of human and SARS-CoV-2 proteins to identify human hub proteins associated with comorbidities., PMID:34655901
Effect of GLP-1 receptor agonist, liraglutide, on muscle in spontaneously diabetic torii fatty rats., PMID:34606964
MicroRNA-26a/b-5p promotes myocardial infarction-induced cell death by downregulating cytochrome c oxidase 5a., PMID:34518647
Transcriptome analysis reveals key genes and pathways associated with egg production in Nandan-Yao domestic chicken., PMID:34509172
Retinoic acid exerts sexually dimorphic effects on muscle energy metabolism and function., PMID:34419449
Dauricine Attenuates Spatial Memory Impairment and Alzheimer-Like Pathologies by Enhancing Mitochondrial Function in a Mouse Model of Alzheimer's Disease., PMID:33634105
Mechanism of Naringenin Blocking the Protection of LTB4/BLT1 Receptor Against Septic Cardiac Dysfunction., PMID:33334792
miR-204/COX5A axis contributes to invasion and chemotherapy resistance in estrogen receptor-positive breast cancers., PMID:32758616
Atco, a yeast mitochondrial complex of Atp9 and Cox6, is an assembly intermediate of the ATP synthase., PMID:32413073
Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis., PMID:32375044
COX5A over-expression protects cortical neurons from hypoxic ischemic injury in neonatal rats associated with TPI up-regulation., PMID:32349668
Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes., PMID:32291341
For research use only. Not for human or drug use.
