Catalog No.
RHD49203
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:500-1:1000, IP: 1:100-1:200, WB: 1:500-1:1000
Target
Protein-glutamine deamidase TGM2, TGase II, Heart G alpha(h), Erythrocyte transglutaminase, Protein-glutamine gamma-glutamyltransferase 2, TG(C), Transglutaminase C, Protein-glutamine serotonyltransferase TGM2, tTG, tTgase, Transglutaminase-2, Protein-glutamine noradrenalinyltransferase TGM2, TGM2, TG2, TGase C, Protein G alpha(h), Protein-glutamine histaminyltransferase TGM2, Tissue transglutaminase, hhG alpha(h), G(h), hTG2, Transglutaminase H, Protein-glutamine dopaminyltransferase TGM2, TGC, Isopeptidase TGM2, TGase-2, TGase H, Transglutaminase II
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P21980
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3G03
Note
For research use only.
Intestinal anti-tissue transglutaminase antibodies in potential coeliac disease., PMID:23199325
Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity., PMID:23425695
The role of TG2 in regulating S100A4-mediated mammary tumour cell migration., PMID:23469180
Tissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma., PMID:23765377
TGM2 inhibition attenuates ID1 expression in CD44-high glioma-initiating cells., PMID:23877317
Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes., PMID:24222690
High-titre circulating tissue transglutaminase-2 antibodies predict small bowel villous atrophy, but decision cut-off limits must be locally validated., PMID:24325651
Comparison of the neuropoietic activity of gene-modified versus parental mesenchymal stromal cells and the identification of soluble and extracellular matrix-related neuropoietic mediators., PMID:24572070
Intestinal titres of anti-tissue transglutaminase 2 antibodies correlate positively with mucosal damage degree and inversely with gluten-free diet duration in coeliac disease., PMID:24773630
Celiac disease and autoimmunity., PMID:24979198
Upregulation of transglutaminase and ε (γ-glutamyl)-lysine in the Fisher-Lewis rat model of chronic allograft nephropathy., PMID:25143942
Diagnosing coeliac disease and the potential for serological markers., PMID:25266110
[Histological diagnosis and complications of celiac disease. Update according to the new S2k guidelines]., PMID:25820446
Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease., PMID:26001928
Inflammation Mediated Metastasis: Immune Induced Epithelial-To-Mesenchymal Transition in Inflammatory Breast Cancer Cells., PMID:26207636
Transglutaminase 2 May Be Associated with Peri-implant Gingival Overgrowth: Preliminary Assessments., PMID:26523722
Recent Advances in Celiac Disease., PMID:27278238
Interpretation of serological tests in the diagnosis of celiac disease: Anti-deamidated gliadin peptide antibodies revisited., PMID:27452003
Immunohistochemical Expression of Antitissue Transglutaminase 2 in Tissue Injuries: An Interpretation Beyond Celiac Disease., PMID:27753658
Biochemical characterization of the medaka (Oryzias latipes) orthologue for mammalian tissue-type transglutaminase (TG2)., PMID:27855535
No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease., PMID:27864127
Intestinal Production of Anti-Tissue Transglutaminase 2 Antibodies in Patients with Diagnosis Other Than Celiac Disease., PMID:28934109
Intestinal anti-transglutaminase 2 immunoglobulin A deposits in children at risk for coeliac disease (CD): data from the PreventCD study., PMID:29114847
Avoiding Small Intestinal Biopsies for Diagnosis of Celiac Disease in Children: A Reliable Strategy for All Patients?, PMID:29135820
B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2., PMID:31727780
Osteopontin contributes to late-onset asthma phenotypes in adult asthma patients., PMID:32009132
HLA-DQ genotype and biochemical characterization of anti-transglutaminase 2 antibodies in patients with type 1 diabetes mellitus in Taiwan., PMID:32362042
Evaluation of Ocular Parameters in Adult Patients with Celiac Disease., PMID:32508197
Dietary Gluten and Neurodegeneration: A Case for Preclinical Studies., PMID:32751379
Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation., PMID:32793209
Differentiating Staphylococcus infection-associated glomerulonephritis and primary IgA nephropathy: a mass spectrometry-based exploratory study., PMID:33057112
Proteomics-Informed Identification of Luminal Targets For In Situ Diagnosis of Inflammatory Bowel Disease., PMID:33159915
The Role of Autophagy-Mediated Dengue Virus Antibody-Dependent Enhancement Infection of THP-1 Cells., PMID:33202415
Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition., PMID:33638284
Celiac Disease After Administration of Immune Checkpoint Inhibitors: A Case Report., PMID:34975913
Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack., PMID:35046049
Tissue transglutaminase activates integrin-linked kinase and β-catenin in ovarian cancer., PMID:35810788
Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines., PMID:37160910
Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease., PMID:37368893
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis., PMID:37424036
Identification of inflammatory biomarkers in IgA nephropathy using the NanoString technology: a validation study in Caucasians., PMID:38291238
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease., PMID:38552723
Bioorthogonal labeling and enrichment of histone monoaminylation reveal its accumulation and regulatory function in cancer cell chromatin., PMID:38562869
pH-Controlled chemoselective rapid azo-coupling reaction (CRACR) enables global profiling of serotonylation proteome in cancer cells., PMID:38766043
Bioorthogonal Labeling and Enrichment of Histone Monoaminylation Reveal Its Accumulation and Regulatory Function in Cancer Cell Chromatin., PMID:38848464
pH-Controlled Chemoselective Rapid Azo-Coupling Reaction (CRACR) Enables Global Profiling of Serotonylation Proteome in Cancer Cells., PMID:39208062
A guide to selecting high-performing antibodies for Protein-glutamine gamma-glutamyltransferase 2 (TGM2) for use in western blot, immunoprecipitation and immunofluorescence., PMID:39220380
Enhancing substrate specificity of microbial transglutaminase for precise nanobody labeling., PMID:39552758
Critical Role for Transglutaminase 2 in Scleroderma Skin Fibrosis and in the Development of Dermal Sclerosis in a Mouse Model of Scleroderma., PMID:39800950
Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis., PMID:40327404
For research use only. Not for human or drug use.
