Catalog No.
YHD37701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro19-Pro261
Predicted molecular weight
29.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20151
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Kallikrein-2, Tissue kallikrein-2, KLK2, hGK-1, Glandular kallikrein-1
Comparative functional analyses of the prostate-specific KLK3 enzyme in primates reveal the impact of sexual selection., PMID:39878341
Towards the identification of body fluids using RT-LAMP isothermal amplification coupled with CRISPR-Cas12a., PMID:39488143
Developmental Therapeutics in Metastatic Prostate Cancer: New Targets and New Strategies., PMID:39272956
Extracellular Domain of IL-10 Receptor Chain-2 (IL-10R2) and Its Arginine-Containing Peptides Are Susceptible Substrates for Human Prostate Kallikrein-2 (KLK2)., PMID:39106042
Stockholm3 in a Multiethnic Cohort for Prostate Cancer Detection (SEPTA): A Prospective Multicentered Trial., PMID:39038251
A Phase 0 Study to Assess the Biodistribution and Pharmacokinetics of a Radiolabeled Antibody Targeting Human Kallikrein 2 in Participants with Metastatic Castration-Resistant Prostate Cancer., PMID:38782459
Manzamine A reduces androgen receptor transcription and synthesis by blocking E2F8-DNA interactions and effectively inhibits prostate tumor growth in mice., PMID:38605607
Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2., PMID:38396898
KLK7, KLK10, and KLK11 in Papillary Thyroid Cancer: Bioinformatic Analysis and Experimental Validation., PMID:38316654
Antagonism of androgen receptor signaling by aloe-emodin., PMID:37806336
Comparative proteome and serum analysis identified FSCN1 as a marker of abiraterone resistance in castration-resistant prostate cancer., PMID:37634036
Quercetin can be a more reliable treatment for metastatic prostate cancer than the localized disease: An in vitro study., PMID:37232542
Prognostic impact of kallikrein-related peptidase transcript levels in prostate cancer., PMID:37139608
Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response., PMID:36608299
The effect of mesenchymal stem cells-derived exosomes on the prostate, bladder, and renal cancer cell lines., PMID:36463254
Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line., PMID:35568821
Human prostate cancer cell epithelial-to-mesenchymal transition as a novel target of arsenic trioxide and curcumin therapeutic approach., PMID:35487055
Mipsagargin: The Beginning-Not the End-of Thapsigargin Prodrug-Based Cancer Therapeutics., PMID:34946547
Combination therapy with novel androgen receptor antagonists and statin for castration-resistant prostate cancer., PMID:34843630
Case Study of Noni Extract in Men with Very Low-Risk or Low-Risk Prostate Cancer., PMID:34661119
Individual Patient Data Meta-analysis of Discrimination of the Four Kallikrein Panel Associated With the Inclusion of Prostate Volume., PMID:34450175
Genetic polymorphisms at 19q13.33 are associated with [-2]proPSA (p2PSA) levels and provide additional predictive value to prostate health index for prostate cancer., PMID:34254325
Cyclopentenone-Containing Tetrahydroquinoline and Geldanamycin Alkaloids from Streptomyces malaysiensis as Potential Anti-Androgens against Prostate Cancer Cells., PMID:34225450
A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer., PMID:34085829
Anti-androgenic effect of astaxanthin in LNCaP cells is mediated through the aryl hydrocarbon-androgen receptors cross talk., PMID:33694182
Identification of coding region SNPs from specific and sensitive mRNA biomarkers for the deconvolution of the semen donor in a body fluid mixture., PMID:33610949
BRG1 knockdown inhibits proliferation through multiple cellular pathways in prostate cancer., PMID:33596994
Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence., PMID:33326447
Proteomic Profiling of Two Distinct Populations of Extracellular Vesicles Isolated from Human Seminal Plasma., PMID:33114768
KLK3 and TMPRSS2 for molecular lymph-node staging in prostate cancer patients undergoing radical prostatectomy., PMID:32978525
Identification of key genes and pathways in castrate-resistant prostate cancer by integrated bioinformatics analysis., PMID:32853947
Synergistic Interaction of Histone Deacetylase 6- and MEK-Inhibitors in Castration-Resistant Prostate Cancer Cells., PMID:32754596
Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer., PMID:32628300
Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy., PMID:32532924
Structure-based discovery of the endocrine disrupting effects of hydraulic fracturing chemicals as novel androgen receptor antagonists., PMID:32505947
All change in the prostate cancer diagnostic pathway., PMID:32112055
Identification of potential biomarkers and pivotal biological pathways for prostate cancer using bioinformatics analysis methods., PMID:31598425
Anti-androgenic effect of 6-formylindolo[3,2-b]carbazole (FICZ) in LNCaP cells is mediated by the aryl hydrocarbon-androgen receptors cross-talk., PMID:31586605
Inhibition of autophagy enhances the anticancer effect of enzalutamide on bladder cancer., PMID:31574376
Biofluid quantification of TWEAK/Fn14 axis in combination with a selected biomarker panel improves assessment of prostate cancer aggressiveness., PMID:31500625
Pan-cancer analysis of clinical relevance of alternative splicing events in 31 human cancers., PMID:31391553
Characterization of seminal plasma proteomic alterations associated with the IVF and rescue-ICSI pregnancy in assisted reproduction., PMID:31364287
Brain cytochrome-c-oxidase as a marker of mitochondrial function: A pilot study in major depression using NIRS., PMID:31111623
Y08197 is a novel and selective CBP/EP300 bromodomain inhibitor for the treatment of prostate cancer., PMID:31097763
Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer., PMID:31043681
MicroRNA-3162-5p-Mediated Crosstalk between Kallikrein Family Members Including Prostate-Specific Antigen in Prostate Cancer., PMID:31018918
A Sample-to-Targeted Gene Analysis Biochip for Nanofluidic Manipulation of Solid-Phase Circulating Tumor Nucleic Acid Amplification in Liquid Biopsies., PMID:30461262
Identification and characterization of novel fusion genes in prostate cancer by targeted RNA capture and next-generation sequencing., PMID:30307468
Riluzole induces AR degradation via endoplasmic reticulum stress pathway in androgen-dependent and castration-resistant prostate cancer cells., PMID:30280407
BAF53A regulates androgen receptor-mediated gene expression and proliferation in LNCaP cells., PMID:30278885
For research use only. Not for human or drug use.
