Catalog No.
EHD37601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ala388
Predicted molecular weight
43.4 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20142
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PGC, Gastricsin, Pepsinogen C
Alpha-asarone relieves nasal inflammation, epithelial barrier damage, and mitochondrial damage in allergic rhinitis by inhibiting mitochondrial ROS via the SIRT1/PGC-1α pathway., PMID:40514518
Estradiol inhibits endometrial injury by promoting the stability of the KLF15 protein and the recovery of mitochondrial function., PMID:40513792
Hypoglycemic episodes exacerbate skeletal muscle insulin resistance in type 2 diabetes mellitus., PMID:40510897
An In Vitro Gut-Liver-Adipose Axis Model to Evaluate the Anti-Obesity Potential of a Novel Probiotic-Polycosanol Combination., PMID:40509530
Brief Weekly Magnetic Field Exposure Enhances Avian Oxidative Muscle Character During Embryonic Development., PMID:40508230
Endarachne binghamiae Ameliorates Hepatic Steatosis, Obesity, and Blood Glucose via Modulation of Metabolic Pathways and Oxidative Stress., PMID:40507912
A natural thiophene from Eclipta prostrata (L.) combats obesity by enhancing adipocytes thermogenesis in high-fat diet-fed obese mice., PMID:40505954
Uncovering the pharmacological mechanisms of bifendate against chronic kidney disease using computational pharmacology and experimental verification., PMID:40505415
Umbelliferone attenuates diabetic sarcopenia by modulating mitochondrial quality and the ubiquitin-proteasome system., PMID:40483791
PGC-1α Promotes NSCLC Progression via FOXM1 Interaction and MUC1 Upregulation., PMID:40481667
Ginsenoside Rg1 Downregulates miR-9-5p Expression to Modulate SIRT1-Mediated Mitochondrial Dysfunction and Ameliorate Alzheimer's Disease., PMID:40478516
Fermented ginseng powder enriched with rare ginsenosides ameliorates high-fat diet-induced obesity by modulating adipogenesis and inflammation., PMID:40475063
Anti-obesity effects of superparamagnetic iron oxide nanoparticles mediated through modulation of hepatic lipolysis and mitochondrial biogenesis., PMID:40473063
Mult-omics analysis reveals the lipid-lowering effects of sea buckthorn and milk thistle solid beverage in hyperlipidemic rats., PMID:40472616
Plant essential oil supplementation promotes growth and attenuates LPS-induced acute liver injury through SIRT1/PGC-1α signaling pathway in nursery pigs., PMID:40468731
The impact of exercise on mitochondrial biogenesis in skeletal muscle: A systematic review and meta-analysis of randomized trials., PMID:40459444
Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway., PMID:40458823
Chrysin Mitigates Chromium-Induced Nephrotoxicity Via Modulation of AMPK/SIRT1/NF-κB/p53 Signaling Cascade and PGC-1α Signaling., PMID:40457156
Depot-Specific Changes in Gene Expression in the Inguinal and Epididymal Adipose Tissues in Response to the High-Intensity Interval Training and Moderate-Intensity Continuous Training in Mice., PMID:40451204
Protective Effect of FABP5 Against 6-OHDA Induced Parkinson's Disease Via PPARγ/SIRT1/PGC-1α Signaling Pathway., PMID:40445460
Weissella confusa Attenuates Cognitive Deficits in Alzheimer's Disease by Reducing Oxidative Stress Via the SIRT1/PGC-1α Signaling Pathway., PMID:40445426
Circulating mitochondrial biomarkers in acute coronary syndrome., PMID:40443515
IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner., PMID:40436019
Protective Effects of a Standardized Water Extract from the Stem of Ipomoea batatas L. Against High-Fat Diet-Induced Obesity., PMID:40431382
Long-Term Functional and Structural Renoprotection After Experimental Acute Kidney Injury in Subclinical Chronic Kidney Disease In Vivo., PMID:40429761
Functional Equivalence of Insulin and IGF-1 in the In Vitro Culture of Chicken Primordial Germ Cells., PMID:40428303
Isorhamnetin Attenuates Isoproterenol-Induced Myocardial Injury by Reducing ENO1 (Alpha-Enolase) in Cardiomyocytes., PMID:40427461
Engeletin Targets Mitochondrial Dysfunction to Attenuate Oxidative Stress and Experimental Colitis in Intestinal Epithelial Cells Through AMPK/SIRT1/PGC-1α Signaling., PMID:40427406
Icariin mitigates depressive-like behavior in rats by regulating mitochondrial function., PMID:40425078
Integrated Metabolomics and Lipidomics Analysis Reveals the Mechanism Behind the Action of Chiglitazar on the Protection Against Sepsis-Induced Acute Lung Injury., PMID:40422869
Non-Redundant Essential Roles of Proteasomal Ubiquitin Receptors Rpn10 and Rpn13 in Germ Cell Formation and Fertility., PMID:40422199
Neuroprotective effect of folic acid by maintaining DNA stability and mitochondrial homeostasis through the ATM/CHK2/P53/PGC-1α pathway in alcohol-exposed mice., PMID:40421718
Maternal β-Nicotinamide Mononucleotide Supplementation Reduces the IUGR Rate by Improving Mitochondrial Function in the Placenta of Sows via AMPK/PGC-1α Pathway., PMID:40420689
[Curcumin inhibits lipid metabolism in non-small cell lung cancer by downregulating the HIF-1α pathway]., PMID:40415436
[Shenqi Buzhong Formula ameliorates mitochondrial dysfunction in a rat model of chronic obstructive pulmonary disease by activating the AMPK/SIRT1/PGC-1α pathway]., PMID:40415428
RNA-binding proteins DND1 and NANOS3 cooperatively suppress the entry of germ cell lineage., PMID:40410171
Peptide YY fragment PYY1-36 disrupts mitochondrial biogenesis via RBM43-dependent PGC-1α translation inhibition., PMID:40404898
Nanoparticle-mediated targeting of PGC-1α reveals critical metabolic pathways in bladder cancer metastasis., PMID:40404885
SIRT1 and its SUMOylation attenuate hyperoxia-induced lung injury by improving mitochondrial biogenesis and fusion., PMID:40403939
Regulating peroxisome proliferator activated receptor gamma coactivator-1alpha (PGC-1α): A potential role in neurological disorder and treatment., PMID:40403826
Protein Acetylation in Age-Related Macular Degeneration: Mechanisms, Roles, and Therapeutic Perspectives., PMID:40402519
Exosomes derived from umbilical cord blood NK cells inhibit the progression of pancreatic cancer by targeting ROS-mediated mitochondrial dysfunction., PMID:40397293
Yi-Fei-Tong-Bi Decoction Alleviates Bleomycin Induced Pulmonary Fibrosis in Mice., PMID:40391179
[Electroacupuncture activates PKA / CREB signaling pathway to promote browning of white fat in obese rats]., PMID:40390613
Inhibitory effects of high extracellular L-glutamate concentrations on skeletal myogenesis., PMID:40389489
Vitexin mitigates AIM2 inflammasome-mediated mitochondrial dysfunction and neuroinflammation in chronic constriction injury induced neuropathy model., PMID:40388859
SIRT3 is required for the protective function of ketogenic diet on neural inflammation and neuropathic pain., PMID:40384870
A combinatorial siRNA and mRNA approach for obesity treatment using targeting lipid nanoparticles., PMID:40383157
Exosome miR-152-3p derived from small intestinal epithelium modulates aging process in adipocytes., PMID:40375937
SOX7: Autism associated gene identified by analysis of multi-Omics data., PMID:40373085
For research use only. Not for human or drug use.
