Catalog No.
EHD37501
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-His259
Predicted molecular weight
29.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20138
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, CD33, gp67, SIGLEC3
Monoclonal Antibodies Against Myeloid Leukemia Cells: Current Knowledge and Future Directions., PMID:40429716
Multiplex base editing to protect from CD33 directed drugs for immune and gene therapy., PMID:40425554
Identification of potential therapeutic drug targets for sepsis by combining the human plasma proteome and genome: a Mendelian randomization study., PMID:40400956
Responses to checkpoint inhibition in metastatic triple negative breast cancer driven by divergent myeloid phenotypes., PMID:40382442
Coupling relationship between glucose and oxygen metabolisms to serve as an imaging biomarker for Alzheimer's disease., PMID:40374876
The genetic risk factors, molecular pathways, microRNAs, and the gut microbiome in Alzheimer's disease., PMID:40374065
Role of CD33 basophils in mediating the effect of lipidome on chronic kidney disease: A 2-sample, 2-variable, bidirectional Mendelian randomization analysis., PMID:40355216
Mechanism of SMYD2 promoting stemness maintenance of bladder cancer stem cells by regulating PYCR1 expression and PINK1/Parkin mitophagy pathway., PMID:40341538
Generation of a Severe Hemophilia A Humanized Mouse Model Capable of Inducing an Anti-FVIII Immune Response., PMID:40300593
Comprehensive immunogenomic landscape analysis unveils CD33 + myeloid cell-driven immunomodulatory signatures in melanoma development., PMID:40300524
Identifying Modifiers of CAR T-Cell Therapeutic Efficacy and Safety: A Systematic Review and Individual Patient Data Meta-Analysis., PMID:40280037
Presence of LILRB4 SNP rs1048801 modulates acute myeloid leukemia progression and inhibits CD4+ T cells proliferation., PMID:40275747
CD33-D2 isoform characterization for advancement of its therapeutic potential., PMID:40272002
Multiplexed Detection of Tumor Markers and Discrimination of Cancer Cell Types by Laser Ablation-Dielectric Barrier Discharge Ionization-Mass Spectrometry., PMID:40262027
Immunophenotypic Profiling of Acute Promyelocytic Leukemia: Insights From a Large Cohort., PMID:40251942
Ginseng extract and total ginsenosides protect the function of hematopoietic stem cells by activating the Notch and Wnt signal pathways., PMID:40216043
B-ALL with CD34 Negative and Surface Immunoglobulin Light Chain Restricted Expression., PMID:40209787
Multi-targeted, NOT gated CAR-T cells as a strategy to protect normal lineages for blood cancer therapy., PMID:40191207
Aptamer- vs Fab-Conjugated Liposomes: A Comparative Study in Targeting Acute Myeloid Leukemia Cells., PMID:40148126
Mediating Role of Blood Metabolites in the Relationship Between Immune Cell Traits and Heart Failure: A Mendelian Randomization and Mediation Analysis., PMID:40079309
A review of antibody-based immunotherapy clinical trials for adult acute myeloid leukemia (AML): monoclonal antibodies (mAbs) and beyond., PMID:40069930
Structure of the CD33 Receptor and Implications for the Siglec Family., PMID:40067740
Delineation of monocytic and early-stage myeloid-derived suppressor cells in the peripheral blood of patients with hepatocarcinoma., PMID:40052651
Human CD33 deficiency is associated with mild alteration of circulating white blood cell counts., PMID:40043053
STING activation improves T-cell-engaging immunotherapy for acute myeloid leukemia., PMID:40009483
Frontline Therapy of AML in the Fit and Younger Population-Incorporating Molecularly Targeted Agents., PMID:39960013
Phase 1 study of lintuzumab-Ac225 combined with CLAG-M salvage therapy in relapsed/refractory acute myeloid leukemia., PMID:39955432
Protection of CD33-modified hematopoietic stem cell progeny from CD33-directed CAR T cells in rhesus macaques., PMID:39928955
Influence of immune cells and inflammatory factors on Alzheimer's disease axis: evidence from mediation Mendelian randomization study., PMID:39910474
Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies., PMID:39893165
Causal relationships between immune cells, inflammatory factors, and preeclampsia: A two-step, two-sample mendelian randomization study., PMID:39864339
SMEPPI: An indenone derivative that selectively inhibits M1 macrophage activation and enhances phagocytic activity., PMID:39813787
c-JUN interacts with HDAC1 as a potential combinatorial therapeutic target in acute myeloid leukemia., PMID:39721452
The Significance of Detecting an Unusual Myeloblast Immunophenotype in a Presumptive Clinical Diagnosis of Myelodysplastic Syndromes., PMID:39711284
Prognostic value of myeloid-derived suppressor-like cells in acute myeloid leukemia: insights from immunophenotyping and clinical correlations., PMID:39673675
Association of immunity-related gene SNPs with Alzheimer's disease., PMID:39651329
Deciphering proteins in Alzheimer's disease: A new Mendelian randomization method integrated with AlphaFold3 for 3D structure prediction., PMID:39637861
Honing CAR T cells to tackle acute myeloid leukemia., PMID:39630061
CD33-CD123 IF-THEN Gating Reduces Toxicity while Enhancing the Specificity and Memory Phenotype of AML-Targeting CAR-T Cells., PMID:39624992
CD133-targeted afatinib nanomicelles for enhanced lung cancer theranostics., PMID:39601387
Evaluation of Gemtuzumab Ozogamicin and Anthracycline Dosing for Favorable Risk Acute Myeloid Leukemia., PMID:39601208
The AXL-mediated modulation of myeloid-derived suppressor cells (MDSC) in nasopharyngeal carcinoma., PMID:39592496
Multi-Omic Analysis Reveals the Impact of Bortezomib in Hyperleukocytic Acute Myeloid Leukemia., PMID:39584619
CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual-targeting antibody overcome antigen heterogeneity in AML., PMID:39571145
Consistent genes associated with structural changes in clinical Alzheimer's disease spectrum., PMID:39554844
Targeting splicing for hematological malignancies therapy., PMID:39528914
Loop33 × 123 CAR-T targeting CD33 and CD123 against immune escape in acute myeloid leukemia., PMID:39535595
Distinctive grade based on Ki67 index and immune microenvironment of metastatic pancreatic neuroendocrine tumors responding to capecitabine plus temozolomide., PMID:39511555
Tryptophan-immunoadsorption plasmapheresis regulates polymorphonuclear-myeloid-derived suppressor cells and pro-inflammatory cytokines., PMID:39508126
Automated and closed clinical-grade manufacturing protocol produces potent NK cells against neuroblastoma cells and AML blasts., PMID:39496674
For research use only. Not for human or drug use.
