Catalog No.
YHD37101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu24-Gly423
Predicted molecular weight
46.60 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20061
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HC, TC I, Protein R, Haptocorrin, Transcobalamin I, TC1, TCN1, Transcobalamin-1, TCI, TC-1
Identification of potential diagnostic markers and molecular mechanisms of asthma and ulcerative colitis based on bioinformatics and machine learning., PMID:40443529
TCN1 as an inflammatory regulator in psoriasis: Activation of the NF-κB pathway and potential therapeutic target., PMID:40318273
Finding Potential Drug Targets for Pre-Eclampsia Using Mendelian Randomisation and Colocalisation Analysis., PMID:40028697
Multi-omic biomarker panel in pancreatic cyst fluid and serum predicts patients at a high risk of pancreatic cancer development., PMID:39747972
Cord Blood Proteomic Profiles, Birth Weight, and Early Life Growth Trajectories., PMID:38743419
Gene expression in multiple sclerosis during pregnancy based on integrated bioinformatics analysis., PMID:38154347
Protein-centric omics integration analysis identifies candidate plasma proteins for multiple autoimmune diseases., PMID:38143258
Biomarkers prediction and immune landscape in ulcerative colitis: Findings based on bioinformatics and machine learning., PMID:38070204
Differences in gene expression profiles in early and late stage rhodesiense HAT individuals in Malawi., PMID:38055777
TCN1 Expression Is Increased in Asthma., PMID:37586352
Construction of a genomic instability-derived predictive prognostic signature for non-small cell lung cancer patients., PMID:37579716
Transcriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza., PMID:37533854
Drug resistance related genes in lung adenocarcinoma predict patient prognosis and influence the tumor microenvironment., PMID:37322027
Reference intervals and stability of haptocorrin and holotranscobalamin in Danish children and elderly., PMID:37209861
Systematic analysis of myocardial immune progression in septic cardiomyopathy: Immune-related mechanisms in septic cardiomyopathy., PMID:36911241
Establishment of a Lymph Node Metastasis-Associated Prognostic Signature for Lung Adenocarcinoma., PMID:36793937
Clinical relevance of vitamin B12 level and vitamin B12 metabolic gene variation in pulmonary tuberculosis., PMID:36275653
A Novel Secreted Protein-Related Gene Signature Predicts Overall Survival and Is Associated With Tumor Immunity in Patients With Lung Adenocarcinoma., PMID:35719915
Proteogenomic characterization of cholangiocarcinoma., PMID:35716043
TCN1 Deficiency Inhibits the Malignancy of Colorectal Cancer Cells by Regulating the ITGB4 Pathway., PMID:35686504
Diagnostic and Therapeutic Perspectives Associated to Cobalamin-Dependent Metabolism and Transcobalamins' Synthesis in Solid Cancers., PMID:35631199
TCN1 is a potential prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma., PMID:35287670
Identification and Verification of Five Potential Biomarkers Related to Skin and Thermal Injury Using Weighted Gene Co-Expression Network Analysis., PMID:35047008
Web-based transcriptome analysis determines a sixteen-gene signature and associated drugs on hearing loss patients: A bioinformatics approach., PMID:34758154
Clinicopathological Analysis and Prognostic Assessment of TCN1 in Patients with Gastric Cancer., PMID:34549663
Single-cell analysis pinpoints distinct populations of cytotoxic CD4+ T cells and an IL-10+CD109+ TH2 cell population in nasal polyps., PMID:34389612
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes., PMID:34145303
Identification of potential gene signatures associated with osteosarcoma by integrated bioinformatics analysis., PMID:34123594
Identification of key candidate biomarkers for severe influenza infection by integrated bioinformatical analysis and initial clinical validation., PMID:33448094
Proteins associated with neutrophil degranulation are upregulated in nasopharyngeal swabs from SARS-CoV-2 patients., PMID:33079950
Identification of Significant Genes in HIV/TB via Bioinformatics Analysis., PMID:33067206
Clinicopathological Analysis and Prognostic Assessment of Transcobalamin I (TCN1) in Patients with Colorectal Tumors., PMID:32753569
High expression of TCN1 is a negative prognostic biomarker and can predict neoadjuvant chemosensitivity of colon cancer., PMID:32686693
Circulating mRNA and microRNA profiling analysis in patients with ischemic stroke., PMID:32626985
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia: A comparison among participants between 2 and 53 years., PMID:32323402
Bioinformatic Analysis Suggests That Three Hub Genes May Be a Vital Prognostic Biomarker in Pancreatic Ductal Adenocarcinoma., PMID:32216644
Alterations in innate immunity and epithelial cell differentiation are the molecular pillars of hidradenitis suppurativa., PMID:31838778
Impaired expression of innate immunity-related genes in IgG4-related disease: A possible mechanism in the pathogenesis of IgG4-RD., PMID:31116057
Epigenetic profiling and mRNA expression reveal candidate genes as biomarkers for colorectal cancer., PMID:30672027
Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance., PMID:30139959
Transcobalamin I: a novel prognostic biomarker of neoadjuvant chemotherapy in locally advanced hypopharyngeal squamous cell cancers., PMID:30100732
Orchestrating a biomarker panel with lncRNAs and mRNAs for predicting survival in pancreatic ductal adenocarcinoma., PMID:29923223
A common TCN1 loss-of-function variant is associated with lower vitamin B12 concentration in African Americans., PMID:29764838
Significant transcriptome and cytokine changes in hepatitis B vaccine non-responders revealed by genome-wide comparative analysis., PMID:29580160
Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma., PMID:28933920
Overexpression of Transcobalamin 1 is an Independent Negative Prognosticator in Rectal Cancers Receiving Concurrent Chemoradiotherapy., PMID:28638446
GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians., PMID:28334792
Association study between genome-wide significant variants of vitamin B12 metabolism and gastric cancer in a han Chinese population., PMID:26959381
Comparative Transcriptome Analysis of Shoots and Roots of TNG67 and TCN1 Rice Seedlings under Cold Stress and Following Subsequent Recovery: Insights into Metabolic Pathways, Phytohormones, and Transcription Factors., PMID:26133169
Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population., PMID:25948668
For research use only. Not for human or drug use.
