Catalog No.
RHC87202
Species reactivity
Human, Mouse, Monkey
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Applications
ELISA, FCM, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:10000, FCM: 1:200-1:400, WB: 1:500-1:2000 |
Target
Ras-related protein Ral-A, RAL, RALA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P11233
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3C50
Note
For research use only.
Identification of multiple ral gene products in human platelets that account for some but not all of the platelet Gn-proteins., PMID:2105235
Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA., PMID:1903399
Identification of some of the brain Gn27 as the ral gene product. Comparison between the brain and platelet Gn-proteins., PMID:1544424
Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21., PMID:1379346
Involvement of Ral GTPase in v-Src-induced phospholipase D activation., PMID:7477381
Generation of antibodies specific for the RalA and RalB GTP-binding proteins and determination of their concentration and distribution in human platelets., PMID:8972729
Immunodetection of ralA and ralB GTP-binding proteins in various rat tissues and platelets., PMID:9543348
Small GTP-binding protein RalA associates with Weibel-Palade bodies in endothelial cells., PMID:10494784
Role for phospholipase D in receptor-mediated endocytosis., PMID:11134345
The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42., PMID:12517963
Phosphorylation of 46-kDa protein of synaptic vesicle membranes is stimulated by GTP and Ca2+/calmodulin., PMID:12526085
RalA-exocyst-dependent recycling endosome trafficking is required for the completion of cytokinesis., PMID:17028198
R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes., PMID:17344481
Large-scale quantitative LC-MS/MS analysis of detergent-resistant membrane proteins from rat renal collecting duct., PMID:18596208
Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein., PMID:19299511
Autoantibodies to tumor-associated antigens combined with abnormal alpha-fetoprotein enhance immunodiagnosis of hepatocellular carcinoma., PMID:19683863
Immunogenicity of Ra1A and its tissue-specific expression in hepatocellular carcinoma., PMID:19822090
Phosphorylation of RalB is important for bladder cancer cell growth and metastasis., PMID:20940393
Analyzing the function of small GTPases by microinjection of plasmids into polarized epithelial cells., PMID:21673637
Ral GTPases regulate cell-mediated cytotoxicity in NK cells., PMID:21810610
Response to MLN8237 in pancreatic cancer is not dependent on RalA phosphorylation., PMID:24222664
Mini-array of multiple tumor-associated antigens (TAAs) in the immunodiagnosis of esophageal cancer., PMID:24761876
Preferential autoimmune response in prostate cancer to cyclin B1 in a panel of tumor-associated antigens., PMID:24860838
Genes involved in pericyte-driven tumor maturation predict treatment benefit of first-line FOLFIRI plus bevacizumab in patients with metastatic colorectal cancer., PMID:25069475
Evaluation and characterization of anti-RalA autoantibody as a potential serum biomarker in human prostate cancer., PMID:27286458
Probing Functional Changes in Exocyst Configuration with Monoclonal Antibodies., PMID:27376061
Serum autoantibodies against a panel of 15 tumor-associated antigens in the detection of ovarian cancer., PMID:28618923
Evaluation of serum autoantibodies against tumor-associated antigens as biomarkers in lung cancer., PMID:29022480
Multi-panel assay of serum autoantibodies in colorectal cancer., PMID:29691673
Using a panel of multiple tumor-associated antigens to enhance the autoantibody detection in the immunodiagnosis of ovarian cancer., PMID:30484895
Development of a ZHER3-Affibody-Targeted Nano-Vector for Gene Delivery to HER3-Overexpressed Breast Cancer Cells., PMID:31531954
Six autoantibodies as potential serum biomarkers of hepatocellular carcinoma: A prospective multicenter study., PMID:32574375
Prevalence of autoantibodies against Ras-like GTPases, RalA, in patients with gastric cancer., PMID:32765875
The immunophilin Zonda controls regulated exocytosis in endocrine and exocrine tissues., PMID:33336828
Possible predictive significance of serum RalA autoantibodies on relapse-free survival in patients with colorectal cancer., PMID:33363728
Multipanel assay of 17 tumor-associated antibodies for serological detection of stage 0/I breast cancer., PMID:33605508
Absolute Quantitation of GTPase Protein Abundance., PMID:33977471
Seroprevalence of Toxocara spp. in children (3-13 years old) in Zahedan, Southeast of Iran., PMID:34295044
Development of recombinant biomimetic nano-carrier for targeted gene transfer to HER3 positive breast cancer., PMID:34455002
Presence of serum RalA and serum p53 autoantibodies in 1833 patients with various types of cancers., PMID:34632560
Six autoantibodies as potential differential biomarkers of hepatocellular carcinoma vs. liver cirrhosis and chronic hepatitis: A prospective multi-institutional study., PMID:36238856
Awaken Immune Cells by Hapten Enhanced Intratumoral Chemotherapy with Penicillin Prolong Pancreatic Cancer Survival., PMID:37283801
Successful targeting in situ of an oncogenic nuclear antigen by hapten induced tumor associated autoantibodies (iTAA)., PMID:37336938
Peptide delivery of a multivalent mRNA SARS-CoV-2 vaccine., PMID:37648082
For research use only. Not for human or drug use.
