Catalog No.
YHD29901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr128-Glu378
Predicted molecular weight
30.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P18564
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ITGB6, Integrin beta-6
Characteristics of cell adhesion molecules expression and environmental adaptation in yak lung tissue., PMID:40158021
Altered structural and transporter-related gene expression patterns in the placenta play a role in fetal demise during Porcine reproductive and respiratory syndrome virus infection., PMID:40119254
Gene expression associated with endocrine therapy resistance in estrogen receptor-positive breast cancer., PMID:40021703
SRF and CBP jointly regulate integrin β6 overexpression in head and neck squamous cell carcinomas., PMID:39848454
Pulmonary exposure to renewable diesel exhaust particles alters protein expression and toxicity profiles in bronchoalveolar lavage fluid and plasma of mice., PMID:39739031
Integrin β6/Annexin A2 axis triggers autophagy to orchestrate hepatocellular carcinoma radioresistance., PMID:39533071
Integrin subunit beta 6 is a potential diagnostic marker for acute kidney injury in patients with diabetic kidney disease: a single cell sequencing data analysis., PMID:39356055
LncRNA SSTR5-AS1 promotes esophageal carcinoma through regulating ITGB6/JAK1/STAT3 signaling., PMID:39234955
ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4+ macrophage infiltration., PMID:39152118
Proteomics identifies potential immunological drivers of postinfection brain atrophy and cognitive decline., PMID:39143319
CRISPR/Cas9-mediated knock out of ITGB6 in human OSCC cells reduced migration and proliferation ability., PMID:38890650
Identification of the cytoplasmic DNA-Sensing cGAS-STING pathway-mediated gene signatures and molecular subtypes in prostate cancer., PMID:38877472
TGFβ signaling pathway in salivary gland tumors., PMID:38479278
ITGB6 promotes pancreatic fibrosis and aggravates the malignant process of pancreatic cancer via JAK2/STAT3 signaling pathway., PMID:38418753
A Neanderthal haplotype introgressed into the human genome confers protection against membranous nephropathy., PMID:38367960
The association and clinicopathological significance of Integrin alphavbeta6 and Rac1 expression in gastric carcinoma., PMID:38344200
A liquid biomarker signature of inflammatory proteins accurately predicts early pancreatic cancer progression during FOLFIRINOX chemotherapy., PMID:38335839
Acidity-induced ITGB6 promote migration and invasion of lung cancer cells by epithelial-mesenchymal transition and focal adhesion., PMID:38316250
Machine Learning Developed a MYC Expression Feature-Based Signature for Predicting Prognosis and Chemoresistance in Pancreatic Adenocarcinoma., PMID:38245886
Exosomal ITGB6 from dormant lung adenocarcinoma cells activates cancer-associated fibroblasts by KLF10 positive feedback loop and the TGF-β pathway., PMID:38205211
Exploring the role of ITGB6: fibrosis, cancer, and other diseases., PMID:38127283
Laminin 332 expression levels predict clinical outcomes and chemotherapy response in patients with pancreatic adenocarcinoma., PMID:37779898
A novel multi-ancestry proteome-wide Mendelian randomization study implicates extracellular proteins, tubular cells, and fibroblasts in estimated glomerular filtration rate regulation., PMID:37774922
Prognostic value and potential molecular mechanism of ITGB superfamily members in hepatocellular carcinoma., PMID:37603520
Functions for platelet factor 4 (PF4/CXCL4) and its receptors in fibroblast-myofibroblast transition and fibrotic failure of arteriovenous fistulas (AVFs)., PMID:37589266
The Transcriptome Landscape of the In Vitro Human Airway Epithelium Response to SARS-CoV-2., PMID:37569398
PANoptosis-related molecular subtype and prognostic model associated with the immune microenvironment and individualized therapy in pancreatic cancer., PMID:37519797
Downregulation of Tumor Promotor Genes in Oryza Sativa Linn.-Induced Antiproliferative Activity of Human Squamous Carcinoma Cells., PMID:37505777
Disrupted epithelial permeability as a predictor of severe COVID-19 development., PMID:37422701
Upregulation of ITGB6 in primary palmar hyperhidrosis., PMID:37212774
Membrane tension-mediated stiff and soft tumor subtypes closely associated with prognosis for prostate cancer patients., PMID:37179366
Plasma proteomic profiling reveals KRT19 could be a potential biomarker in patients with anti-MDA5+ dermatomyositis., PMID:37160775
Novel ITGB6 variants cause hypoplastic-hypomineralized amelogenesis imperfecta and taurodontism: characterization of tooth phenotype and review of literature., PMID:37041139
Impact of polystyrene microplastic exposure on gilthead seabream (Sparus aurata Linnaeus, 1758): Differential inflammatory and immune response between anterior and posterior intestine., PMID:37011684
Hair Follicle Transcriptome Analysis Reveals Differentially Expressed Genes That Regulate Wool Fiber Diameter in Angora Rabbits., PMID:36979137
An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma., PMID:36840413
Silencing DTX3L Inhibits the Progression of Cervical Carcinoma by Regulating PI3K/AKT/mTOR Signaling Pathway., PMID:36614304
A novel focal adhesion-related risk model predicts prognosis of bladder cancer -- a bioinformatic study based on TCGA and GEO database., PMID:36357874
Expression levels of NPPB, ITGB6, CPNE4, EML5, and ITSN1 in fresh exudates swabbed from critically colonised and infected full-thickness wounds in rats., PMID:36307995
FOXO1 inhibits FSL-1 regulation of integrin β6 by blocking STAT3 binding to the integrin β6 gene promoter., PMID:36299623
Protocadherin B9 Is Associated with Tumorigenesis and Cancer Progression in Colorectal Cancer., PMID:35533651
Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation., PMID:35524442
Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer., PMID:35392966
Protocadherin B9 Is Associated with Human Esophageal Squamous Cell Carcinoma Progression., PMID:35390792
Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells., PMID:35188070
CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapy., PMID:35132075
Inhibition of integrin αvβ6 sparks T-cell antitumor response and enhances immune checkpoint blockade therapy in colorectal cancer., PMID:35131862
Inhibition of β-catenin signaling attenuates arteriovenous fistula thickening in mice by suppressing myofibroblasts., PMID:35062862
Integrin αvβ6 contributes to the development of intestinal fibrosis via the FAK/AKT signaling pathway., PMID:34979108
Identification of Therapeutic Targets and Prognostic Biomarkers Among Integrin Subunits in the Skin Cutaneous Melanoma Microenvironment., PMID:34660316
For research use only. Not for human or drug use.
