Catalog No.
YHD27901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala36-Gln325
Predicted molecular weight
33.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P18065
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BP2, IBP-2, IGFBP2, IGF-binding protein 2, Insulin-like growth factor-binding protein 2, IGFBP-2, IBP2
Single Cell Spatial Profiling Identifies Region-Specific Extracellular Matrix Adhesion and Signaling Networks in Glioblastoma., PMID:40496929
Alkaline Treatment Enhances the Anti-inflammatory and Reparative Potential of Dentin Matrix Proteins in Inflamed Pulp., PMID:40484223
IGFBP-2 and IGF-II: Key Components of the Neural Stem Cell Niche? Implications for Glioblastoma Pathogenesis., PMID:40429889
Innovating Glioma Therapy Using Secretions from Umbilical Cord Mesenchymal Stem Cells to Target Homeobox and Growth Factor Genes., PMID:40421391
Human Plasma Proteomics Links Modifiable Lifestyle Exposome to Disease Risk., PMID:40385387
An analysis of prognostic risk and immunotherapy response of glioblastoma patients based on single-cell landscape and nitrogen metabolism., PMID:40348204
Epidermal Loss of PRMT5 Leads to the Emergence of an Atypical Basal Keratinocyte-Like Cell Population and Defective Epidermal Stratification., PMID:40339790
The predictive value of a prognostic risk model constructed for three aging-associated genes in glioma., PMID:40302497
Predictive models and WTAP targeting for idiopathic pulmonary fibrosis (IPF)., PMID:40287490
Plasma Insulin-Like Growth Factor-Binding Protein-2 Levels Predict Severe Septic Acute Kidney Injury: A Mendelian Randomization Analysis., PMID:40231291
Role of Ca2+/calmodulin and PI3K/AKT signaling pathways and active ingredients of BaoTaiYin in treatment of recurrent miscarriage., PMID:40201242
An integrated proteomic classifier to distinguish benign from malignant pulmonary nodules., PMID:40189512
The special phenotypic characteristics of Dummerstorf superfertile mouse lines could depend on the expression levels of IGF-axis genes., PMID:40158446
Circ-ITCH promotes the ubiquitination degradation of HOXC10 to facilitate osteogenic differentiation in disuse osteoporosis through stabilizing BRCA1 mRNA via IGF2BP2-mediated m6A modification., PMID:40148953
Alveolar epithelial type 2 cell specific loss of IGFBP2 activates inflammation in COVID-19., PMID:40121473
Targeted proteomics of serum IGF-I, -II, IGFBP-2, -3, -4, -5, -6 and ALS., PMID:40116411
miR-192-2 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells by Targeting IGFBP2 in Zhedong White Geese., PMID:40075946
Post-lactation mass recovery and metabolic hormone dynamics in adult female Weddell seals., PMID:40074089
Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities., PMID:40061343
Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities., PMID:40032831
Transcriptomic analysis of broiler chickens reveals metabolic adaptations to a reduced crude protein diet., PMID:39983527
Differential Expression of BCL2 and IGFBP2 in Childhood Immune Thrombocytopenic Purpura Clinical Subtypes: Implications for Predicting Disease Progression and Apoptotic Regulation., PMID:39905592
Integration of Gastric Cancer RNA-Seq Datasets Along With PPI Network Suggests That Nonhub Nodes Have the Potential to Become Biomarkers., PMID:39854135
P2Y1R-IGFBP2 signaling: new contributor to astrocyte-neuron communication., PMID:39825982
Triple‑negative breast cancer cell‑derived piR‑31115 promotes the proliferation and migration of endothelial cells via METTL3‑mediated m6A modification of YAP1., PMID:39820521
IGFBP2 and IGFBP4 interact to activate complement pathway in diabetic kidney disease., PMID:39806768
Association of serum PD-L1 and IGFBP-2 levels with prognosis in patients with esophageal carcinoma., PMID:39799446
Multi-miRNAs-Mediated Hepatic Lepr Axis Suppression: A Pparg-Dicer1 Pathway-Driven Mechanism in Spermatogenesis for the Intergenerational Transmission of Paternal Metabolic Syndrome., PMID:39792613
Diagnostic Accuracy of a Blood-Based Biomarker Panel for Colorectal Cancer Detection: A Pilot Study., PMID:39766076
IGFBP2 Promotes Proliferation and Glycolysis of Endometrial Cancer by Regulating PKM2/HIF-1α Axis., PMID:39761954
Plasma biomarkers in patients with age-related sarcopenia: a proteomic exploration and experimental validation., PMID:39725826
Aerobic exercise inhibits GSDME-dependent myocardial cell pyroptosis to protect ischemia-reperfusion injury., PMID:39719560
A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro., PMID:39714446
The potential of circulating free DNA of methylated IGFBP as a biomarker for type 2 diabetes Mellitus: A Comprehensive review., PMID:39706247
Comprehensive analysis of skin growth-related hub genes and microenvironment characterization in a mouse expanded skin model., PMID:39703504
Endothelial FUNDC1 Deficiency Drives Pulmonary Hypertension., PMID:39655444
Role of miRNA regulation in IGFBP-2 overexpression and neuronal ferroptosis: Insights into the Nrf2/SLC7A11/GPX4 pathway in Alzheimer's disease., PMID:39653234
HIG-2 promotes glioma stemness and radioresistance mediated by IGFBP2-rich microparticles in hypoxia., PMID:39633113
High-temperature exposure during the early embryonic stage lowers core body temperature after growth via a hypothalamic Igfbp2-dependent mechanism., PMID:39627352
Insulin-Like Growth Factor Binding Protein 2 Predicts Right Ventricular Reverse Remodeling and Improvement of Concomitant Tricuspid Regurgitation After Transcatheter Edge-to-Edge Mitral Valve Repair., PMID:39600082
Distinct Patterns of Smooth Muscle Phenotypic Modulation in Thoracic and Abdominal Aortic Aneurysms., PMID:39590192
IGFBP-2 in Critical Illness: A Prognostic Marker in the Growth Hormone/Insulin-like Growth Factor Axis., PMID:39585162
Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer., PMID:39531506
Spatial transcriptomics analysis identifies therapeutic targets in diffuse high-grade gliomas., PMID:39530009
Cytokine profile of cerebrospinal fluid in pediatric patients with metastatic medulloblastoma., PMID:39524698
Characterization of a novel IGFBP-2 transcript in the ovarian granulosa cells of chicken follicles: mRNA expression, function and effect of reproductive hormones and IGF1., PMID:39504834
Temporal trajectory and left ventricular ejection fraction association of eight circulating biomarkers in first acute myocardial infarction patients: a 12-month prospective cohort study., PMID:39474118
Integrative 3D genomics with multi-omics analysis and functional validation of genetic regulatory mechanisms of abdominal fat deposition in chickens., PMID:39468045
Effect of Time-Restricted Eating on Circulating Levels of IGF1 and Its Binding Proteins in Obesity: An Exploratory Analysis of a Randomized Controlled Trial., PMID:39458471
Insulin-Like Growth Factor Binding Protein 2 Drives Neurodegeneration in Parkinson's Disease: Insights From In Vivo and In Vitro Studies., PMID:39412224
For research use only. Not for human or drug use.
