Catalog No.
EHD27401
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ile328
Predicted molecular weight
37.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P17948
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FLT1, Vascular endothelial growth factor receptor 1, VEGFR1, Vascular permeability factor receptor, FRT, Tyrosine-protein kinase receptor FLT, VEGFR-1, FLT, FLT-1, Tyrosine-protein kinase FRT, Fms-like tyrosine kinase 1
Epigollatecatechin gallate alleviates rheumatoid arthritis through PI3K-Akt pathway by inhibiting FLT1., PMID:40449273
Overexpression of hsa-HLA-DRB1 may delay diabetic wound healing and angiogenesis by regulating miRNA_12118 and FLT-1., PMID:40419622
Assessment of a salivary cfRNA biomarker panel to predict preeclampsia., PMID:40393217
Identification of 1,400 metabolites as mediators of obesity in 473 gut microbiota taxa: a mediation Mendelian randomization study., PMID:40372036
The role of maternal age, markers of ultrasound, sFlt-1 and CA125 serum levels in the prediction of miscarriage: Study acronym: MIS-CARE (markers of ultrasound, immunologic and serum factors in the comprehensive analysis of the risks for early pregnancy loss)., PMID:40345104
Aspirin reverses the inhibitory effect of soluble fms-like tyrosine kinase-1 on trophoblast invasiveness and ciliogenesis through Sonic hedgehog signaling in preeclampsia., PMID:40339344
Placental biomarker and fetoplacental Doppler abnormalities are strongly associated with placental pathology in pregnancies with small-for-gestational-age fetus: prospective study., PMID:40329845
Delivery of Itgb1-siRNA by triptolide-modified and anti-Flt1 peptide-guided ionizable cationic LNPs for targeted therapy of corneal neovascularization., PMID:40324532
The VEGF decoy receptor soluble Fms-like tyrosine kinase 1 binds to macrophages., PMID:40314836
Correlation between maternal hemodynamic and sFlt-1/PlGF ratio in pregnancies affected by hypertensive disorders and fetal growth restriction., PMID:40311221
Cyst fluid proteins stratify malignant risk of intraductal papillary mucinous neoplasm of the pancreas., PMID:40300662
The Impact of Cannabidiol (CBD) on Lipid Absorption and Lymphatic Transport in Rats., PMID:40292467
scRNA-seq reveals that VEGF signaling mediates the response to neoadjuvant anlotinib combined with PD-1 blockade therapy in non-small cell lung cancer., PMID:40281576
Beyond antibodies: Beta-2 glycoprotein I as the unsung guardian of pregnancy., PMID:40279303
Evaluating the role of astragalus polysaccharide in modulating immune infiltration and enhancing prognostic biomarkers in pediatric acute myeloid leukemia., PMID:40260377
Maternal and cord serum levels of sFlt-1 and PlGF in pregnancies complicated by gestational diabetes mellitus: a prospective cohort study., PMID:40254554
Placenta at single-cell resolution in early and late preeclampsia: insights and clinical implications., PMID:40253080
Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression., PMID:40246836
PRERISK Study: A Randomized Controlled Trial Evaluating a sFlt-1/PlGF-Based Calculator for Preeclampsia Hospitalization., PMID:40238908
Pomegranate Juice Alleviates Preeclampsia Symptoms in an L-NAME-Induced Rat Model: A Dose-Dependent Study., PMID:40218901
[Identification of endothelial cell key genes associated with pathogenesis and invasion of human venous malformations using single-nucleus RNA sequencing-based co-expression network analysis]., PMID:40176667
Exploring new predictors for hypertensive disorders of pregnancy., PMID:40174313
Total and Free Placental Growth Factor Levels During Preeclampsia and Fetal Growth Restriction., PMID:40171652
Ferulic acid inhibits ox-LDL-induced ferroptosis and apoptosis in RAW 264.7 cells via the HIF-1 signaling pathway., PMID:40170728
sFlt-1/PlGF ratio combined with endocan-1 serum levels improves the predictive values for the occurrence and prognosis of preeclampsia in a single centre study., PMID:40133446
Placental Biomarker Testing for Evaluation of Suspected Preeclampsia., PMID:40129181
Intraamniotic vitamin D preserves lung development and prevents pulmonary hypertension in experimental bronchopulmonary dysplasia due to intraamniotic sFlt-1., PMID:40125892
Bioinformatics analysis explores key pathways and hub genes in central precocious puberty., PMID:40110745
Contribution of alterations in peritubular capillary density and microcirculation to the progression of tubular injury and kidney fibrosis., PMID:40103536
Molecular mechanism of Flt-1 protein and the regulation of monocytes modulate endothelial cell in wound healing sites via PGF/FLT1 signaling., PMID:40101823
Exploring biomarkers of systemic oxidative stress and placental insufficiency in pregnant women with inflammatory bowel diseases., PMID:40089080
N-terminal pro B-type natriuretic peptide as biomarker to predict pre-eclampsia and maternal-fetal complications., PMID:40088200
PlGF and sFlt-1, reduced fetal movements and adverse delivery outcome of a likely placental cause: A real world prospective observational study., PMID:40058951
A systematic review of first-trimester blood biomarkers associated with preterm prelabor rupture of the fetal membranes., PMID:40048392
FLT1 and other candidate fetal haemoglobin modifying loci in sickle cell disease in African ancestries., PMID:40025045
A Review of the Diagnosis, Risk Factors, and Role of Angiogenetic Factors in Hypertensive Disorders of Pregnancy., PMID:40007059
The Angiogenic Markers PlGF and sFlt-1 in Cytomegalovirus Infection During Pregnancy: Insights from a Clinical Case., PMID:40007022
Amniotic fluid-derived exosomal miR-146a-5p ameliorates preeclampsia phenotypes by inhibiting HIF-1α/FLT-1 expression., PMID:39987849
Predictive performance of sFlt-1, PlGF and the sFlt-1/PlGF ratio for preeclampsia: A systematic review and meta-analysis., PMID:39947348
A novel TLR4 accessory molecule drives hepatic oncogenesis through tumor-associated macrophages., PMID:39929433
Massively elevated sFlt1/PlGF in a pregnant patient with fetal growth restriction and perinatal death in the context of a systemic lupus erythematosus., PMID:39914866
Preeclampsia biomarkers (sFlt-1/PlGF) dynamics are not disrupted by SARS-CoV-2 infection during pregnancy in a hypertensive disorder SARS-CoV-2 vaccinated cohort., PMID:39892161
Angiogenic factors alone or in combination with ultrasound Doppler criteria for risk classification among late-onset small fetuses with or without pre-eclampsia., PMID:39888184
sFlt-1, Coagulation Function, and Platelets as Predictors of Preeclampsia., PMID:39884357
A prospective observational multicenter cohort study of maternal serum sFlt-1 and PlGF concentration in prediction of adverse neonatal outcomes in small for gestational age newborns delivered ≥34 weeks of gestation., PMID:39880468
Evaluation of the utility of the sFlt-1/PlGF ratio in pregnancy complicated by pre-eclampsia - single-center study. Preliminary analysis., PMID:39878757
MFN2-mediated decrease in mitochondria-associated endoplasmic reticulum membranes contributes to sunitinib-induced endothelial dysfunction and hypertension., PMID:39848488
4-Octyl Itaconate Alleviates Myocardial Ischemia-Reperfusion Injury Through Promoting Angiogenesis via ERK Signaling Activation., PMID:39836624
Neonatal cost savings in hypertensive disorders of pregnancy: Economic evaluation of the sFlt-1/PlGF test with real world implementation of biomarkers., PMID:39826331
Trophoblast-derived factors drive human mesenchymal stem cell differentiation along an endothelial lineage: A model of early placental vasculogenesis., PMID:39823693
For research use only. Not for human or drug use.
