Catalog No.
RHC10503
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, SRP27, Heat shock protein beta-1, Stress-responsive protein 27, HspB1, 28 kDa heat shock protein, HSPB1, HSP27, HSP28, HSP 27
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P04792
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2Y88
Luminex-based pilot study identifies novel serum autoantibodies associated with disease activity in patients with lupus nephritis., PMID:40500568
Evidence that extracellular HSPB1 contributes to inflammation in alcohol-associated hepatitis., PMID:39281760
crVDAC3 alleviates ferroptosis by impeding HSPB1 ubiquitination and confers trastuzumab deruxtecan resistance in HER2-low breast cancer., PMID:39243601
Heat shock protein 27 in the pathogenesis of COVID-19 and non-COVID acute respiratory distress syndrome., PMID:37966617
FYN/TOPK/HSPB1 axis facilitates the proliferation and metastasis of gastric cancer., PMID:37016377
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP., PMID:35235182
Physical activity level (PAL) and risk factors of cardiovascular disease in the MASHAD study cohort., PMID:34739910
Quaternary Structure and Hetero-Oligomerization of Recombinant Human Small Heat Shock Protein HspB7 (cvHsp)., PMID:34360542
Are IgG antibodies to heat shock proteins HSP27 and HSP60 useful markers in endometrial cancer and cervical cancer?, PMID:33914318
HSP25 Vaccination Attenuates Atherogenesis via Upregulation of LDLR Expression, Lowering of PCSK9 Levels and Curbing of Inflammation., PMID:33792343
Synergistic effect of collagen and CXCL12 in the low doses on human platelet activation., PMID:33119719
Evaluation of ABO blood group in subjects with CVD risk factors in a population sample from northeastern Iran., PMID:32905941
Serum levels of anti-heat shock protein 27 antibodies in patients with chronic liver disease., PMID:32895883
Prognostic Factors Associating with Pro-oxidant-antioxidant Balance; Neutrophils to Lymphocytes Ratio, Vitamin D, Heat Shock Protein 27, and Red Cell Distribution Width., PMID:32111498
Damage-Associated Molecular Patterns and Myeloid-Derived Suppressor Cells in Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease Patients., PMID:31355298
Biophysical analyses and functional implications of the interaction between Heat Shock Protein 27 and antibodies to HSP27., PMID:31136785
Depression in adolescent girls: Relationship to serum vitamins a and E, immune response to heat shock protein 27 and systemic inflammation., PMID:30981058
Hsp-27 and NF-κB pathway is associated with AR/AR-V7 expression in prostate cancer cells., PMID:30807779
Is the small heat shock protein HspB1 (Hsp27) a real and predominant target of methylglyoxal modification?, PMID:30756294
Significance of serum antibodies against HPV E7, Hsp27, Hsp20 and Hp91 in Iranian HPV-exposed women., PMID:30755156
Anemia is associated with cognitive impairment in adolescent girls: A cross-sectional survey., PMID:30661397
Calcineurin/P38MAPK/HSP27-dependent pathways are involved in the attenuation of postischemic mitochondrial injury afforded by sodium bicarbonate co-transporter (NBCe1) inhibition., PMID:30615862
Downregulation of heat shock factor 4 transcription activity via MAPKinase phosphorylation at Serine 299., PMID:30316871
Comparative proteomic analysis reveals different responses in porcine lymph nodes to virulent and attenuated homologous African swine fever virus strains., PMID:30208957
The Effects of Curcumin on Serum Heat Shock Protein 27 Antibody Titers in Patients with Metabolic Syndrome., PMID:29958053
Chemokine CC-motif ligand 2 participates in platelet function and arterial thrombosis by regulating PKCα-P38MAPK-HSP27 pathway., PMID:29864522
Small heat shock protein speciation: novel non-canonical 44 kDa HspB5-related protein species in rat and human tissues., PMID:29542021
HSP27-Mediated Extracellular and Intracellular Signaling Pathways Synergistically Confer Chemoresistance in Squamous Cell Carcinoma of Tongue., PMID:29246940
Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function., PMID:28915917
Effect of Crocin on Antibody Titers to Heat-Shock Protein 27 in Subjects with Metabolic Syndrome., PMID:28486907
Relationship between serum anti-heat shock protein 27 antibody levels and obesity., PMID:28237841
Heat shock protein 27 is a potential indicator for response to YangZheng XiaoJi and chemotherapy agents in cancer cells., PMID:27600495
Course of serum autoantibodies in patients after acute angle-closure glaucoma attack., PMID:27758063
Expression of Heat Shock Protein 27 in Melanoma Metastases Is Associated with Overall Response to Bevacizumab Monotherapy: Analyses of Predictive Markers in a Clinical Phase II Study., PMID:27166673
Dp71Δ78-79 dystrophin mutant stimulates neurite outgrowth in PC12 cells via upregulation and phosphorylation of HspB1., PMID:26936078
Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease., PMID:26001928
Identification of heat shock protein 27 as a novel autoantigen of Behçet's disease., PMID:25529454
The effects of wet cupping on serum high-sensitivity C-reactive protein and heat shock protein 27 antibody titers in patients with metabolic syndrome., PMID:25146067
Barberry treatment reduces serum anti-heat shock protein 27 and 60 antibody titres and high-sensitivity c-reactive protein in patients with metabolic syndrome: a double-blind, randomized placebo-controlled trial., PMID:24536039
Lysine deacetylase inhibition promotes relaxation of arterial tone and C-terminal acetylation of HSPB6 (Hsp20) in vascular smooth muscle cells., PMID:24400135
Synergistic effect of lung tumor-associated dendritic cell-derived HB-EGF and CXCL5 on cancer progression., PMID:24346967
The role of estrogen receptor-α in estrogen-mediated regulation of basal and exercise-induced Hsp70 and Hsp27 expression in rat soleus., PMID:24303535
Expression of Hsp27 correlated with rat detrusor contraction after acute urinary retention., PMID:23740515
Effect of zinc supplementation on serum antibody titers to heat shock protein 27 in patients with thalassemia major., PMID:23683800
O-GlcNAcylation of αB-crystallin regulates its stress-induced translocation and cytoprotection., PMID:23543138
Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin α6β4-dependent Akt, GSK-3β, and HSF-1 in mesenchymal stem cells., PMID:23538444
Curcuminoids modulate pro-oxidant-antioxidant balance but not the immune response to heat shock protein 27 and oxidized LDL in obese individuals., PMID:23494802
Antioxidants reduce TGF-beta2-induced gene expressions in human optic nerve head astrocytes., PMID:23280001
Enhanced cell survival and diminished apoptotic response to simulated ischemia-reperfusion in H9c2 cells by magnetic field preconditioning., PMID:22960730
For research use only. Not for human or drug use.
