Catalog No.
YHD26301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Trp24-Pro244
Predicted molecular weight
28.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P17787
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CHRNB2, Neuronal acetylcholine receptor subunit beta-2
CHRNA5-A3-B4, CYP2A6, and DBH Genetic Associations With Smoking Cessation Throughout Adulthood Within Two Longitudinal Studies of Women., PMID:39673390
Cannabinol (CBN) Influences the Ion Channels and Synaptic-Related Genes in NSC-34 Cell Line: A Transcriptomic Study., PMID:39329756
A novel alcohol+nicotine co-use self-administration procedure reveals sex differences and differential alteration of mesocorticolimbic TLR- and cholinergic-related neuroimmune gene expression in rats., PMID:39197504
Clinical, molecular, physiologic, and therapeutic feature of patients with CHRNA4 and CHRNB2 deficiency: A systematic review., PMID:39193833
Increased spontaneous activity and progressive suppression of adult neurogenesis in the hippocampus of rat offspring after maternal exposure to imidacloprid., PMID:39002876
Pathogenic genes implicated in sleep-related hypermotor epilepsy: a research progress update., PMID:38966089
Neonicotinoids differentially modulate nicotinic acetylcholine receptors in immature and antral follicles in the mouse ovary†., PMID:38713677
Circadian clock-related genome-wide mendelian randomization identifies putatively genes for ulcerative colitis and its comorbidity., PMID:38302916
Two novel variants of the STXBP1 and CHRNB2 genes identified in a Chinese boy with refractory seizures and developmental delay., PMID:37706497
BEX2 is poor prognostic factor and required for cancer stemness in gastric cancer., PMID:36933308
Nicotinic acetylcholine receptors and epilepsy., PMID:36796465
CHRNA5-A3-B4 and DRD2 Genes and Smoking Cessation Throughout Adulthood: A Longitudinal Study of Women., PMID:36794842
Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles., PMID:36468138
Continuous Exposure to Alpha-Glycosyl Isoquercitrin from Gestation Ameliorates Disrupted Hippocampal Neurogenesis in Rats Induced by Gestational Injection of Valproic Acid., PMID:36094739
Network Pharmacological Study on the Mechanism of Cynanchum paniculatum (Xuchangqing) in the Treatment of Bungarus multicinctus Bites., PMID:35837378
The β2V287L nicotinic subunit linked to sleep-related epilepsy differently affects fast-spiking and regular spiking somatostatin-expressing neurons in murine prefrontal cortex., PMID:35513164
Nicotinic acetylcholine receptors in a songbird brain., PMID:35344610
Increased Risky Choice and Reduced CHRNB2 Expression in Adult Male Rats Exposed to Nicotine Vapor., PMID:35163155
Atlas of receptor genes expressed by the bovine morula and corresponding ligand-related genes expressed by uterine endometrium., PMID:34596291
Application of Bioinformatics Methods to Identify Key Genes and Functions in Chronic Pelvic Pain., PMID:34381521
Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells., PMID:34331011
Disruption of postnatal neurogenesis and adult-stage suppression of synaptic plasticity in the hippocampal dentate gyrus after developmental exposure to sterigmatocystin in rats., PMID:34126181
An investigation into nicotinic receptor involvement in mood disorders uncovers novel depression candidate genes., PMID:33895417
TSC1 as a Novel Gene for Sleep-Related Hypermotor Epilepsy: A Child with a Mild Phenotype of Tuberous Sclerosis., PMID:33578443
Nicotinic Receptors in Sleep-Related Hypermotor Epilepsy: Pathophysiology and Pharmacology., PMID:33255633
Variants in CHRNB2 and CHRNA4 Identified in Patients with Insular Epilepsy., PMID:32536355
Systems Pharmacology Approach to Investigate the Mechanism of Kai-Xin-San in Alzheimer's Disease., PMID:32317964
Transcriptomic analysis of α-synuclein knockdown after T3 spinal cord injury in rats., PMID:31726970
Reduced adolescent risk-assessment and lower nicotinic beta-2 expression in rats exposed to nicotine through lactation by forcedly drinking dams., PMID:31228592
Twenty-eight-day repeated oral doses of sodium valproic acid increases neural stem cells and suppresses differentiation of granule cell lineages in adult hippocampal neurogenesis of postpubertal rats., PMID:31085223
CHRNA2 and Nocturnal Frontal Lobe Epilepsy: Identification and Characterization of a Novel Loss of Function Mutation., PMID:30809122
Evolution of vertebrate nicotinic acetylcholine receptors., PMID:30700248
Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population., PMID:29666375
[Maternal bonding style, cholinergic receptor gene polymorphisms in association with smoking-related depressive symptoms]., PMID:29411706
Gene Profiling of Nucleus Basalis Tau Containing Neurons in Chronic Traumatic Encephalopathy: A Chronic Effects of Neurotrauma Consortium Study., PMID:29338612
Pharmacogenetic study of seven polymorphisms in three nicotinic acetylcholine receptor subunits in smoking-cessation therapies., PMID:29196725
Reduced α4 subunit expression in α4+- and α4+- /β2+- nicotinic acetylcholine receptors alters α4β2 subtype up-regulation following chronic nicotine treatment., PMID:28585241
Adeno-Associated Viral Vectors Serotype 8 for Cell-Specific Delivery of Therapeutic Genes in the Central Nervous System., PMID:28239341
Altered Expression of Genes Encoding Neurotransmitter Receptors in GnRH Neurons of Proestrous Mice., PMID:27774052
Nicotinic cholinergic and dopaminergic receptor mRNA expression in male and female rats with high or low preference for nicotine., PMID:27428758
SNPs in NRXN1 and CHRNA5 are associated to smoking and regulation of GABAergic and glutamatergic pathways., PMID:27355804
Maternal exposure to ochratoxin A targets intermediate progenitor cells of hippocampal neurogenesis in rat offspring via cholinergic signal downregulation and oxidative stress responses., PMID:27346841
Crucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future research., PMID:27327258
Paroxysmal hypnogenic dyskinesia is associated with mutations in the PRRT2 gene., PMID:27123484
MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes., PMID:26904947
Generalized epilepsy in a family with basal ganglia calcifications and mutations in SLC20A2 and CHRNB2., PMID:26475232
Developmental exposure to T-2 toxin reversibly affects postnatal hippocampal neurogenesis and reduces neural stem cells and progenitor cells in mice., PMID:26314264
Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder., PMID:26184988
Spontaneous epileptic seizures in transgenic rats harboring a human ADNFLE missense mutation in the β2-subunit of the nicotinic acetylcholine receptor., PMID:26091610
For research use only. Not for human or drug use.
