Catalog No.
YHD22901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gln413
Predicted molecular weight
48.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P17174
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GOT1, Cysteine aminotransferase, cytoplasmic, Aspartate aminotransferase, cytoplasmic, Glutamate oxaloacetate transaminase 1, Cysteine transaminase, cytoplasmic, Transaminase A, cAspAT, cCAT
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity., PMID:40437698
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival., PMID:40396212
ANXA1 promotes intrahepatic cholangiocarcinoma proliferation and growth by regulating glutamine metabolism through GOT1 stabilization., PMID:40390008
A novel peptide TCL6148 induces ferroptosis via the GOT1/GPX4 pathway to enhance sunitinib sensitivity in renal cell carcinoma., PMID:40379184
Volvariella volvacea Polypeptide Mitigates Alcohol-Induced Liver Injury: A Multi-Omics Study., PMID:40361639
SFTSV induces liver ferroptosis through m6A-related ferritinophagy., PMID:40340535
Cerebrospinal fluid proteome profiling across the Alzheimer's disease continuum: a step towards solving the equation for 'X'., PMID:40329321
Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis., PMID:40250411
UBR-1 deficiency leads to ivermectin resistance in Caenorhabditis elegans., PMID:40167441
Consistency, distinction, and potential metabolic crosstalk of nitrogen mobilization-related genes in silk production and silk gland biology., PMID:40116023
Sirt6 loss activates Got1 and facilitates cleft palate through abnormal activating glycolysis., PMID:40050262
Applying machine learning to high-dimensional proteomics datasets for the identification of Alzheimer's disease biomarkers., PMID:40033432
Loss of γ-aminobutyric acid D-Type Motor Neurons in Young Adult Caenorhabditis elegans Following Exposition with Silica Nanoparticles., PMID:39936982
Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway., PMID:39936600
mTOR/HIF-1α pathway-mediated glucose reprogramming and macrophage polarization by Sini decoction plus ginseng soup in ALF., PMID:39798342
Multidimensional analyses identify genes of high priority for pancreatic cancer research., PMID:39774001
A Novel circ_0075829/miR-326/GOT1 ceRNA Crosstalk Regulates the Malignant Phenotypes and Drug Sensitivity of Gemcitabine-Resistant Pancreatic Cancer Cells., PMID:39692397
GLP-1R agonist promotes proliferation of neuroendocrine neoplasm cells expressing GLP-1 receptors., PMID:39665969
Effect of food enrichment based on diverse feeding regimes on the immunity of Nibea albiflora by biochemical and RNA-seq analysis of the spleen., PMID:39580873
Asparagine Availability Is a Critical Limiting Factor for Infectious Spleen and Kidney Necrosis Virus Replication., PMID:39459874
Multi-omics integration analysis reveals the molecular mechanisms of drought adaptation in homologous tetraploid alfalfa(Medicago sativa 'Xinjiang-Daye')., PMID:39262125
Plasma proteomics implicate glutamic oxaloacetic transaminases as potential markers for acute myocardial infarction., PMID:39173902
Machine Learning Identify Ferroptosis-Related Genes as Potential Diagnostic Biomarkers for Gastric Intestinal Metaplasia., PMID:39169865
Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection., PMID:39126652
Preserving mitochondrial homeostasis protects against drug-induced liver injury via inducing OPTN (optineurin)-dependent Mitophagy., PMID:39099169
Glutamate oxaloacetate transaminase 1 is dispensable in macrophage differentiation and anti-pathogen response., PMID:38965342
Revealing the Molecular Mechanism of Sageretia theezans in the Treatment of Hemorrhoids based on Network Pharmacology., PMID:38934275
SCG5 and MITF may be novel markers of copper metabolism immunorelevance in Alzheimer's disease., PMID:38871989
Targeting c-Myc transactivation by LMNA inhibits tRNA processing essential for malate-aspartate shuttle and tumour progression., PMID:38769668
Screening for ferroptosis genes related to endometrial carcinoma and predicting of targeted drugs based on bioinformatics., PMID:38758406
SIRT1 maintains bone homeostasis by regulating osteoblast glycolysis through GOT1., PMID:38700532
ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection., PMID:38687642
Glutamine-mediated epigenetic regulation of cFLIP underlies resistance to TRAIL in pancreatic cancer., PMID:38684915
Simultaneous quantification of six proteins related to liver injury using nano liquid chromatography-tandem mass spectrometry., PMID:38605420
Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial-Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma., PMID:38587552
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival., PMID:38586045
Pan-cancer molecular signatures connecting aspartate transaminase (AST) to cancer prognosis, metabolic and immune signatures., PMID:38496547
Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia., PMID:38485816
Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis., PMID:38347496
Serum proteomics reveals a tolerant immune phenotype across multiple pathogen taxa in wild vampire bats., PMID:38193073
Myoglobin improves doxycycline sensitivity in pancreatic cancer through promoting heme oxygenase-1-mediated ferroptosis., PMID:38115220
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue., PMID:38036981
Correction of symptoms of Huntington disease by genistein through FOXO3-mediated autophagy stimulation., PMID:37992314
Integrating multiple microarray datasets to explore the significance of ferroptosis regulators in the diagnosis and subtype classification of osteoarthritis., PMID:37960823
Applying HDACis to increase SSTR2 expression and radiolabeled DOTA-TATE uptake: from cells to mice., PMID:37907154
The Integration of Genome-Wide DNA Methylation and Transcriptomics Identifies the Potential Genes That Regulate the Development of Skeletal Muscles in Ducks., PMID:37895154
System analysis based on glutamine catabolic-related enzymes identifies GPT2 as a novel immunotherapy target for lung adenocarcinoma., PMID:37657356
Histone H3 K27M-mediated regulation of cancer cell stemness and differentiation in diffuse midline glioma., PMID:37647805
Iron promotes glycolysis to drive colon tumorigenesis., PMID:37579983
Label-free quantitative proteomics reveals the potential mechanisms of insoluble dietary fiber from okara in improving hepatic lipid metabolism of high-fat diet-induced mice., PMID:37499746
For research use only. Not for human or drug use.
