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Recombinant Human GOT1 Protein, N-His

Catalog #:   YHD22901 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P17174
Protein length: Met1-Gln413
Overview

Catalog No.

YHD22901

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Met1-Gln413

Predicted molecular weight

48.56 kDa

Nature

Recombinant

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P17174

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

GOT1, Cysteine aminotransferase, cytoplasmic, Aspartate aminotransferase, cytoplasmic, Glutamate oxaloacetate transaminase 1, Cysteine transaminase, cytoplasmic, Transaminase A, cAspAT, cCAT

Note

For research use only.

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human GOT1
References

Label-free quantitative proteomics reveals the potential mechanisms of insoluble dietary fiber from okara in improving hepatic lipid metabolism of high-fat diet-induced mice., PMID:37499746

Iron promotes glycolysis to drive colon tumorigenesis., PMID:37579983

Histone H3 K27M-mediated regulation of cancer cell stemness and differentiation in diffuse midline glioma., PMID:37647805

System analysis based on glutamine catabolic-related enzymes identifies GPT2 as a novel immunotherapy target for lung adenocarcinoma., PMID:37657356

The Integration of Genome-Wide DNA Methylation and Transcriptomics Identifies the Potential Genes That Regulate the Development of Skeletal Muscles in Ducks., PMID:37895154

Applying HDACis to increase SSTR2 expression and radiolabeled DOTA-TATE uptake: from cells to mice., PMID:37907154

Integrating multiple microarray datasets to explore the significance of ferroptosis regulators in the diagnosis and subtype classification of osteoarthritis., PMID:37960823

Correction of symptoms of Huntington disease by genistein through FOXO3-mediated autophagy stimulation., PMID:37992314

Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue., PMID:38036981

Myoglobin improves doxycycline sensitivity in pancreatic cancer through promoting heme oxygenase-1-mediated ferroptosis., PMID:38115220

Serum proteomics reveals a tolerant immune phenotype across multiple pathogen taxa in wild vampire bats., PMID:38193073

Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis., PMID:38347496

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia., PMID:38485816

Pan-cancer molecular signatures connecting aspartate transaminase (AST) to cancer prognosis, metabolic and immune signatures., PMID:38496547

Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival., PMID:38586045

Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial-Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma., PMID:38587552

Simultaneous quantification of six proteins related to liver injury using nano liquid chromatography-tandem mass spectrometry., PMID:38605420

Glutamine-mediated epigenetic regulation of cFLIP underlies resistance to TRAIL in pancreatic cancer., PMID:38684915

ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection., PMID:38687642

SIRT1 maintains bone homeostasis by regulating osteoblast glycolysis through GOT1., PMID:38700532

Screening for ferroptosis genes related to endometrial carcinoma and predicting of targeted drugs based on bioinformatics., PMID:38758406

Targeting c-Myc transactivation by LMNA inhibits tRNA processing essential for malate-aspartate shuttle and tumour progression., PMID:38769668

SCG5 and MITF may be novel markers of copper metabolism immunorelevance in Alzheimer's disease., PMID:38871989

Revealing the Molecular Mechanism of Sageretia theezans in the Treatment of Hemorrhoids based on Network Pharmacology., PMID:38934275

Glutamate oxaloacetate transaminase 1 is dispensable in macrophage differentiation and anti-pathogen response., PMID:38965342

Preserving mitochondrial homeostasis protects against drug-induced liver injury via inducing OPTN (optineurin)-dependent Mitophagy., PMID:39099169

Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection., PMID:39126652

Machine Learning Identify Ferroptosis-Related Genes as Potential Diagnostic Biomarkers for Gastric Intestinal Metaplasia., PMID:39169865

Plasma proteomics implicate glutamic oxaloacetic transaminases as potential markers for acute myocardial infarction., PMID:39173902

Multi-omics integration analysis reveals the molecular mechanisms of drought adaptation in homologous tetraploid alfalfa(Medicago sativa 'Xinjiang-Daye')., PMID:39262125

Asparagine Availability Is a Critical Limiting Factor for Infectious Spleen and Kidney Necrosis Virus Replication., PMID:39459874

Effect of food enrichment based on diverse feeding regimes on the immunity of Nibea albiflora by biochemical and RNA-seq analysis of the spleen., PMID:39580873

GLP-1R agonist promotes proliferation of neuroendocrine neoplasm cells expressing GLP-1 receptors., PMID:39665969

A Novel circ_0075829/miR-326/GOT1 ceRNA Crosstalk Regulates the Malignant Phenotypes and Drug Sensitivity of Gemcitabine-Resistant Pancreatic Cancer Cells., PMID:39692397

Multidimensional analyses identify genes of high priority for pancreatic cancer research., PMID:39774001

mTOR/HIF-1α pathway-mediated glucose reprogramming and macrophage polarization by Sini decoction plus ginseng soup in ALF., PMID:39798342

Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway., PMID:39936600

Loss of γ-aminobutyric acid D-Type Motor Neurons in Young Adult Caenorhabditis elegans Following Exposition with Silica Nanoparticles., PMID:39936982

Applying machine learning to high-dimensional proteomics datasets for the identification of Alzheimer's disease biomarkers., PMID:40033432

Sirt6 loss activates Got1 and facilitates cleft palate through abnormal activating glycolysis., PMID:40050262

Consistency, distinction, and potential metabolic crosstalk of nitrogen mobilization-related genes in silk production and silk gland biology., PMID:40116023

UBR-1 deficiency leads to ivermectin resistance in Caenorhabditis elegans., PMID:40167441

Mitochondria-organelle crosstalk in establishing compartmentalized metabolic homeostasis., PMID:40250411

Cerebrospinal fluid proteome profiling across the Alzheimer's disease continuum: a step towards solving the equation for 'X'., PMID:40329321

SFTSV induces liver ferroptosis through m6A-related ferritinophagy., PMID:40340535

Volvariella volvacea Polypeptide Mitigates Alcohol-Induced Liver Injury: A Multi-Omics Study., PMID:40361639

A novel peptide TCL6148 induces ferroptosis via the GOT1/GPX4 pathway to enhance sunitinib sensitivity in renal cell carcinoma., PMID:40379184

ANXA1 promotes intrahepatic cholangiocarcinoma proliferation and growth by regulating glutamine metabolism through GOT1 stabilization., PMID:40390008

Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival., PMID:40396212

RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity., PMID:40437698

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human GOT1 Protein, N-His [YHD22901]
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