Catalog No.
YHD22301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Cys387
Predicted molecular weight
44.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P17066
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSP70B', HSPA6, Heat shock 70 kDa protein B', Heat shock 70 kDa protein 6
Exploring heat shock protein-related biomarkers and subgroups in osteoarthritis using Gene Expression Omnibus data sets., PMID:40474128
Recent insights into depression from transcriptomic analysis., PMID:40376285
The Effect of Reduced Dietary Protein on Adipose Tissue in Local Krškopolje Pigs., PMID:40362677
CITED2 Binding to EP300 Regulates Human Spermatogonial Stem Cell Proliferation and Survival Through HSPA6., PMID:40313859
High Glucose-induced transcriptomic changes in human trabecular meshwork cells., PMID:40278947
Effect of electromagnetic field radiation on transcriptomic profile and DNA methylation level in pig conceptuses during the peri-implantation period., PMID:40269194
A novel benzofuran derivative of β-elemene (ZT-22) inhibits hepatocellular carcinoma cell growth via directly targeting HSPA6., PMID:40239884
SARS-CoV-2 S, M, and E Structural Glycoproteins Differentially Modulate Endoplasmic Reticulum Stress Responses., PMID:39940816
Comparative Analysis of Immune Response Genes Induced by a Virulent or Attenuated Strain of Babesia bigemina., PMID:39859202
Pharmacological Modulation of the Unfolded Protein Response as a Therapeutic Approach in Cutaneous T-Cell Lymphoma., PMID:39858470
High Glucose-Induced Transcriptomic Changes in Human Trabecular Meshwork Cells., PMID:39764143
Comparative proteomic analysis reveals the response mechanism of freshwater leech (Whitmania pigra) under heat-stress challenge., PMID:39729945
Machine Learning Analysis of RNA-Seq Data Identifies Key Gene Signatures and Pathways in Mpox Virus-Induced Gastrointestinal Complications Using Colon Organoid Models., PMID:39456924
RNA sequencing comparing centenarian and middle-aged women lymphoblastoid cell lines identifies age-related dysregulated expression of genes encoding selenoproteins, heat shock proteins, CD99, and BID., PMID:39445501
Human coronaviruses activate and hijack the host transcription factor HSF1 to enhance viral replication., PMID:39243335
Enhanced ER protein processing gene expression increases rAAV yield and full capsid ratio in HEK293 cells., PMID:39230729
Transcriptomic Analysis of Newborn Hanwoo Calves: Effects of Maternal Overnutrition during Mid- to Late Pregnancy on Subcutaneous Adipose Tissue and Liver., PMID:38927640
Integration of transcriptome and machine learning to identify the potential key genes and regulatory networks affecting drip loss in pork., PMID:38865489
Heat shock protein-related diagnostic signature and molecular subtypes in ankylosing spondylitis: new pathogenesis insights., PMID:38679420
Identifying SLC2A6 as the novel protective factor in breast cancer by TP53-related genes affecting M1 macrophage infiltration., PMID:38622369
Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons., PMID:38470006
Elotuzumab Enhances CD16-Independent NK Cell-Mediated Cytotoxicity against Myeloma Cells by Upregulating Several NK Cell-Enhancing Genes., PMID:38444839
It is not just about transcription: involvement of brain RNA splicing in substance use disorders., PMID:38396082
Lactate-lactylation-HSPA6 axis promotes PRRSV replication by impairing IFN-β production., PMID:38088561
ROR2 deficit may induce the tetralogy of Fallot via down-regulating of β-catenin/SOX3/HSPA6 in vitro and in vivo., PMID:37749917
PP4R1 accelerates the malignant progression of NSCLC via up-regulating HSPA6 expression and HSPA6-mediated ER stress., PMID:37739270
RNA sequencing reveals the transcriptomic landscape and alternative splicing events induced by LGALS1 silencing in non-small cell lung cancer., PMID:37341175
Hyperthermia promotes M1 polarization of macrophages via exosome-mediated HSPB8 transfer in triple negative breast cancer., PMID:37233869
Identification and Characterization of Proteins That Are Involved in RTP1S-Dependent Transport of Olfactory Receptors., PMID:37175532
SARS-CoV-2 ORF3A interacts with the Clic-like chloride channel-1 (CLCC1) and triggers an unfolded protein response., PMID:37033725
YBX2 modulates mRNA stability via interaction with YTHDF2 in endometrial cancer cells., PMID:37030331
BARX1 promotes osteosarcoma cell proliferation and invasion by regulating HSPA6 expression., PMID:36927457
Analysis of signaling cascades from myeloma cells treated with pristimerin., PMID:36858733
Parkinson's Disease Gene Biomarkers Screened by the LASSO and SVM Algorithms., PMID:36831718
Long term exposure of cigarette smoke condensate (CSC) mediates transcriptomic changes in normal human lung epithelial Beas-2b cells and protection by garlic compounds., PMID:36758788
Integrative analyses of radiation-related genes and biomarkers associated with breast cancer., PMID:36647876
HSPA6, a novel prognostic and therapeutic biomarker, associated with Ming classification in gastric cancer., PMID:36458368
Excessive HSP70/TLR2 activation leads to remodeling of the tumor immune microenvironment to resist chemotherapy sensitivity of mFOLFOX in colorectal cancer., PMID:36244673
Expression profile, subcellular localization of MARCH4 and transcriptome analysis of its potential regulatory signaling pathway in large yellow croaker (Larimichthys crocea)., PMID:36126839
Development of human retinal organoid models for bisphenol toxicity assessment., PMID:36126549
The Glycolysis-derived α-Dicarbonyl Metabolite Methylglyoxal is a UVA-photosensitizer Causing the Photooxidative Elimination of HaCaT Keratinocytes with Induction of Oxidative and Proteotoxic Stress Response Gene Expression†., PMID:36109156
RNA-Seq transcriptome analysis reveals Maackia amurensis leukoagglutinin has antitumor activity in human anaplastic thyroid cancer cells., PMID:36057880
N-Acetyl-L-Cysteine Protects Airway Epithelial Cells during Respiratory Syncytial Virus Infection against Mucin Synthesis, Oxidative Stress, and Inflammatory Response and Inhibits HSPA6 Expression., PMID:36046596
HSP70 upregulation in nasal mucosa of symptomatic children with allergic rhinitis and potential risk of asthma development., PMID:35982171
Porcine endometrial heat shock proteins are differentially influenced by pregnancy status, heat stress, and altrenogest supplementation during the peri-implantation period., PMID:35772767
Porcine Circovirus type 2 infected myocardial tissue transcriptome signature., PMID:35714796
Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors., PMID:35685361
HSPA6 and its role in cancers and other diseases., PMID:35666422
High abundance of CDC45 inhibits cell proliferation through elevation of HSPA6., PMID:35642733
A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway., PMID:35459861
For research use only. Not for human or drug use.
