Long-term antigen exposure irreversibly modifies metabolic requirements for T cell function. PMID: 29911570
Human leukocyte antigen-G and regulatory T cells during specific immunotherapy for pollen allergy. PMID: 24022071
[Ever more humanized mice for new therapeutic applications]. PMID: 25388574
CD25-expressing B-lymphocytes in rheumatic diseases. PMID: 17257224
Lower proportions of CD4+CD25(high) and CD4+FoxP3, but not CD4+CD25+CD127(low) FoxP3+ T cell levels in children with autoimmune thyroid diseases. PMID: 23249428
Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid, IL-2R gamma(null) mice in vivo. PMID: 19748990
Differential reconstitution of T cell subsets following immunodepleting treatment with alemtuzumab (anti-CD52 monoclonal antibody) in patients with relapsing-remitting multiple sclerosis. PMID: 24198283
Circulating follicular regulatory T cells could inhibit Ig production in a CTLA-4-dependent manner but are dysregulated in ulcerative colitis. PMID: 31442916
Production of IgG2 Antibodies to Pneumococcal Polysaccharides After Vaccination of Treated HIV Patients May Be Augmented by IL-7Ralpha Signaling in ICOS(+) Circulating T Follicular-Helper Cells. PMID: 31068934
Blockade of IL-7Rα alleviates collagen-induced arthritis via inhibiting Th1 cell differentiation and CD4+ T cell migration. PMID: 27736699
Rhesus monkey immature monocyte-derived dendritic cells generate alloantigen-specific regulatory T cells from circulating CD4+CD127-/lo T cells. PMID: 19898200
A systematic meta-analysis of immune signatures in patients with COVID-19. PMID: 34260780
Adalimumab specifically induces CD3(+) CD4(+) CD25(high) Foxp3(+) CD127(-) T-regulatory cells and decreases vascular endothelial growth factor plasma levels in refractory immuno-mediated uveitis: a non-randomized pilot intervention study. PMID: 22222264
TLR9 signalling in HCV-associated atypical memory B cells triggers Th1 and rheumatoid factor autoantibody responses. PMID: 31279905
Successful treatment for West syndrome with severe combined immunodeficiency. PMID: 24534054
Anti-CD33 chimeric antigen receptor targeting of acute myeloid leukemia. PMID: 25480499
Monoclonal antibodies to the common gamma-chain as cytokine receptor antagonists in vivo: effect on intrathymic and intestinal intraepithelial T lymphocyte development. PMID: 9620654
IL-7 receptor blockade inhibits IL-17-producing gammadelta cells and suppresses melanoma development. PMID: 24619454
High soluble IL-7 receptor expression in Sjogren's syndrome identifies patients with increased immunopathology and dryness. PMID: 27269297
IL-7 receptor alpha blockade, an off-switch for autoreactive T cells. PMID: 22826232
Large-scale Isolation of Highly Pure "Untouched" Regulatory T Cells in a GMP Environment for Adoptive Cell Therapy. PMID: 26049548
Egg-specific IgE and basophil activation but not egg-specific T-cell counts correlate with phenotypes of clinical egg allergy. PMID: 29518422
Combining anti-IL-7Ralpha antibodies with autoantigen-specific immunotherapy enhances non-specific cytokine production but fails to prevent Type 1 Diabetes. PMID: 30908554
Preoperative carfilzomib and lulizumab based desensitization prolongs graft survival in a sensitized non-human primate model. PMID: 32898569
Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells. PMID: 28746881
Upregulated thymic stromal lymphopoietin receptor expression in children with asthma. PMID: 26999524
The miR-15 family reinforces the transition from proliferation to differentiation in pre-B cells. PMID: 28705801
IL-7-dependent homeostatic proliferation in the presence of a large number of T cells in gld mice. PMID: 15215622
Tezepelumab as an Emerging Therapeutic Option for the Treatment of Severe Asthma: Evidence to Date. PMID: 33536746
Interferon beta treatment of multiple sclerosis increases serum interleukin-7. PMID: 24821684
Anti-IL-7 receptor-alpha treatment ameliorates newly established Sjogren's-like exocrinopathy in non-obese diabetic mice. PMID: 29680668
The hepatitis B vaccine protects re-exposed health care workers, but does not provide sterilizing immunity. PMID: 23916846
Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia. PMID: 29535426
Glomerular common gamma chain confers B- and T-cell-independent protection against glomerulonephritis. PMID: 28111009
Guiding postablative lymphocyte reconstitution as a route toward transplantation tolerance. PMID: 24840180
Altered phenotype and functionality of varicella zoster virus-specific cellular immunity in individuals with active infection. PMID: 25180236
CD20+ B cell depletion alters T cell homing. PMID: 24696233
Ex vivo Stimulation of Lymphocytes with IL-10 Mimics Sepsis-Induced Intrinsic T-Cell Alterations. PMID: 29182416
Increased proportions of functionally impaired regulatory T cell subsets in systemic sclerosis. PMID: 28522286
Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo. PMID: 27199430
Membrane progesterone receptors in human regulatory T cells: a reality in pregnancy. PMID: 25639501
Type 1 innate lymphoid cell aggravation of atherosclerosis is mediated through TLR4. PMID: 29570822
Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes. PMID: 28844471
Innate IFN-γ-Producing Cells Developing in the Absence of IL-2 Receptor Common γ-Chain. PMID: 28687660
Cytomegalovirus Encephalitis in a Patient with Severe Combined Immunodeficiency. PMID: 26546317
Development of an in situ CAR-T cell protocol through optical and PSMA-targeted PET imaging., PMID:40493195
Low-dose radiation by radiopharmaceutical therapy enhances GD2 TRAC-CAR T cell efficacy in localized neuroblastoma., PMID:40465728
Dynamics and immunological signature of γδ T cells following antiretroviral therapy initiation in acute HIV-1 Infection., PMID:40406103
Dose Optimization of rhIL-7-hyFc for Patients With Lymphopenia Using a Neonatal Fc Receptor-Mediated Recycling-Based and Target-Mediated Drug Disposition Pharmacokinetic Model., PMID:40396986
The Human Bone Marrow May Offer an IL-15-Dependent Survival Niche for EOMES+ Tr1-Like Cells., PMID:40375822
An elevated percentage of CD4⁺CD25⁺CD127low regulatory T cells in peripheral blood indicates a poorer prognosis in hepatocellular carcinoma after curative hepatectomy., PMID:40335903
IL-7 in autoimmune diseases: mechanisms and therapeutic potential., PMID:40313966
Reduced interleukin-2 receptor subunit γ expression in Crohn's disease: A potential mechanism for γδ T cell deficiency., PMID:40248067
Deficiency of IL-7R attenuates abdominal aortic aneurysms in mice by inhibiting macrophage polarization towards M1 phenotype through the NF-κB pathway., PMID:40240976
Role of Regulatory T Cells in Chronic Obstructive Pulmonary Disease., PMID:40226513
Quantitative Assessment of T-Regulatory Cell Population and FOXP3 Gene Expression in Chronically Exposed Residents of the Urals Region., PMID:40216726
Decreased gene expression of interleukin 2 receptor subunit γ (CD132) in tissues of patients with Crohn's disease., PMID:40182599
Functional insights of an uncommon hypomorphic variant in IL2RG as a monogenic cause of CVID-like disease with antibody deficiency and T CD4 lymphopenia., PMID:40170851
Construction of enhanced MRI-based radiomics models using machine learning algorithms for non-invasive prediction of IL7R expression in high-grade gliomas and its prognostic value in clinical practice., PMID:40165301
Higher proportions of circulating CXCR3+ CCR6- Tfh cells as a hallmark of impaired CD4+ T-cell recovery in HIV-1-infected immunological non-responders., PMID:40130906
Decreased circulating CD39+ regulatory T cell frequencies following non-traumatic brain death., PMID:40118258
ApoE ε4-dependent Alteration of CXCR3 + CD127+ CD4+ T cells associates with elevated plasma neurofilament light chain in Alzheimer's disease., PMID:40112322
IL-7Rα signaling in regulatory T cells of adipose tissue is essential for systemic glucose homeostasis., PMID:40107286
Humanized Mouse Model of Graft-Versus-Host Disease Utilizing Nonirradiated NOD-scid-IL-2Rγnull Mice., PMID:40100599
T cell receptor usage and epitope specificity amongst CD8+ and CD4+ SARS-CoV-2-specific T cells., PMID:40092978
Pre-B-cell leukemia transcription factor 1 contributes to liver fibrosis by enabling IL-7 signaling in HSC., PMID:40080840
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors., PMID:40074330
LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2., PMID:40066518
In vitro differentiation of common lymphoid progenitor cells into B cell using stromal cell free culture system., PMID:40038600
Cytotoxic KLRG1+ IL-7R- effector CD8+ T cells distinguish kidney transplant recipients controlling cytomegalovirus reactivation., PMID:40028342
Collaboration between interleukin-7 and -15 enables adaptation of tissue-resident and circulating memory CD8+ T cells to cytokine deficiency., PMID:40023156
Causal Association Between Inflammatory Proteins, Inflammatory Cells, and Cauda Equina Syndrome: A Two-Sample Mendelian Randomization., PMID:40020998
Th1-poised naive CD4 T cell subpopulation reflects anti-tumor immunity and autoimmune disease., PMID:40000667
Genome-wide KAS-Seq mapping of leukocytes in ischemia-reperfusion model reveals IL7R as a potential therapeutic target for ischemia-reperfusion injury., PMID:39979392
Surface pTα expression predicts LCK activation and preclinical synergy of LCK and JAK coinhibition in adult T-ALL., PMID:39977715
Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE., PMID:39975551
The development and potent antitumor efficacy of CD44/CD133 dual-targeting IL7Rα-armored CAR-T cells against glioblastoma., PMID:39952598
Transvitreal Retinochoroidal Biopsies of Primary Uveal Melanoma Reveal an Association of Low HLA Class I and High NK Cell Abundance in Low-Risk Disease., PMID:39918475
Phase I study of efineptakin alfa (NT-I7) for the treatment of Kaposi sarcoma., PMID:39915263
A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740
A Phenotypically Distinct Human Th2 Cell Subpopulation Is Associated With Development of Allergic Disorders in Infancy., PMID:39899007
CD8+T cells and monocytes were associated with brain alterations in human immunodeficiency virus-infected individuals with cognitive impairment., PMID:39892581
Regulatory B-Cells Are Associated Negatively With Regulatory T-Cells and Positively With Cytokines in Peripheral Blood of Pregnant Women., PMID:39854121
OMIP-110: A 37-Color Spectral Flow Cytometric Panel to Assess Transcription Factors and Chemokine Receptors in Human Intestinal Lymphoid Cells., PMID:39838760
IL-7 secreted by keratinocytes induces melanogenesis via c-kit/MAPK signaling pathway in Melan-a melanocytes., PMID:39825949
Adaptive immune cells antagonize ILC2 homeostasis via SLAMF3 and SLAMF5., PMID:39792675
Preimplantation genetic testing for four families with severe combined immunodeficiency: Three unaffected livebirths., PMID:39789600
An early precursor CD8+ T cell that adapts to acute or chronic viral infection., PMID:39778710
Optimized BCMA/CS1 bispecific TRuC-T cells secreting IL-7 and CCL21 robustly control multiple myeloma., PMID:39776916
Direct Inhibitory Effect of HTLV-1-Infected T Cells on the Production of Anti-Ro/SS-A Antibody by B Cells from Patients with Sjögren's Syndrome., PMID:39775490
New insights into roles of IL-7R gene as a diagnostic biomarker for post-stroke depression., PMID:39763672
Dynamic P-glycoprotein expression in early and late memory states of human CD8 + T cells and the protective role of ruxolitinib., PMID:39740391
TLS and immune cell profiling: immunomodulatory effects of immunochemotherapy on tumor microenvironment in resectable stage III NSCLC., PMID:39726591
The role of TIGIT-CD226-PVR axis in mediating T cell exhaustion and apoptosis in NSCLC., PMID:39725799
A minority of Th1 and Tfh effector cells express survival genes shared by memory cell progeny that require IL-7 or TCR signaling to persist., PMID:39723889
For research use only. Not for human or drug use.
