Catalog No.
YHD18001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln25-Asp234
Predicted molecular weight
26.73 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P16471
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PRLR, PRL-R, Prolactin receptor
Lifetime Variations of Prolactin Receptor Isoforms mRNA in the Hippocampus and Dentate Gyrus of the Rat-Effects of Aging., PMID:40507839
Regulatory effects of lncRNA PVT1 on transcriptome in human breast cancer MDA-MB-231 cell line determined by in silico analyses., PMID:40464801
High plasma prolactin is associated with PRL-R and predicts poor prognosis in Chinese postmenopausal women with breast cancer., PMID:40377604
Prolactin Mediates Distinct Time Course Regulation of Tyrosine Hydroxylase Phosphorylation and Gene Expression in Tuberoinfundibular Dopaminergic Neurons of Female Rats., PMID:40358166
A prolactin-targeting antibody to prevent stress-induced peripheral nociceptor sensitization and female postoperative pain., PMID:40354542
Prolactin maintains the neonatal phenotype of enterocytes during lactation in newborn mice., PMID:40353577
c-Jun regulates postpartum β-cell apoptosis and survival downstream of prolactin signaling., PMID:40350071
Vaccarin treats lactation insufficiency through the ALKBH5-SFRP2-Wnt/β-catenin signaling pathway., PMID:40311715
Prolactin modulation of thermoregulatory circuits provides resilience to thermal challenge of pregnancy., PMID:40215163
Production and Functional Verification of 8-Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-Edited Donor Pigs for Xenotransplantation., PMID:40190036
Exploring the impact of chia seeds and matcha green tea on gene expression related to the puberty pathway in growing male New Zealand white rabbits., PMID:40172761
A novel clinically relevant antagonistic interplay between prolactin and oncogenic YAP-CCN2 pathways as a differentiation therapeutic target in breast cancer., PMID:40157909
Sex-related gene expression in the posterodorsal medial amygdala of cycling female rats along with prolactin modulation of lordosis behavior., PMID:40147695
Association of Genes TRH, PRL and PRLR with Milk Performance, Reproductive Traits and Heat Stress Response in Dairy Cattle., PMID:40076589
c-Jun regulates postpartum β-cell apoptosis and survival downstream of prolactin signaling., PMID:40060458
Pre-gestational restraint stress affects reproductive outcomes in adult rats by modulating ovarian and uterine function., PMID:40015659
Genome-Wide Identification and Characterization of gh/prl/sl Family in Cynoglossus semilaevis., PMID:40004051
Association of Selected STAT Inhibitors with Prolactin-Induced Protein (PIP) in Breast Cancer., PMID:40003884
Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene., PMID:39947597
Proline cis/trans Conformational Selection Controls 14-3-3 Binding., PMID:39909402
Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice., PMID:39819370
Potential Candidate Genes Associated with Litter Size in Goats: A Review., PMID:39795025
Immunization with OPN5 increased seasonal degradation of reproductive activity in Magang ganders., PMID:39754930
Crosstalk between prolactin, insulin-like growth factors, and thyroid hormones in feather growth regulation in neonatal chick wings., PMID:39701429
Systemic and mammary inflammation and mammary gland development of Holstein dairy cows around dry-off and calving., PMID:39662814
The Impact of Dietary Encapsulated Fennel Seed (Foeniculum vulgare Mill.) Essential Oil Inclusion Levels on Performance, Serum Hormone Profiles, and Expression of Reproductive Axis-Related Genes in the Early and Late Laying Phases of Hens., PMID:39655356
Prolactin locally mediates follicular atresia in hyperprolactinemic vizcachas (Rodentia, Chinchillidae)., PMID:39642982
Evaluating ovarian follicles and their steroid hormone gene expression patterns in a high egg-producing research turkey line., PMID:39616679
Long-term iodine deficiency and excess inhibit β-casein and α-lactalbumin secretion of milk in lactating rats., PMID:39603394
Prolactin-specific induction of the nuclear translocation of porcine prolactin receptor in porcine mammary epithelial cells., PMID:39561513
Prolactin deficiency drives diabetes-associated cognitive dysfunction by inducing microglia-mediated synaptic loss., PMID:39543619
The goat PRLR gene: mRNA expression, association analysis of InDel variants with body weight and growth traits., PMID:39522661
The TCONS_00046732/chi-miR-135b-5p/PRLR regulatory axis promotes endometrial epithelial cells growth through the PI3K-Akt signaling pathway., PMID:39505183
Prolactin: structure, receptors, and functions., PMID:39476210
Prolactin Modulates the Proliferation and Secretion of Goat Mammary Epithelial Cells via Regulating Sodium-Coupled Neutral Amino Acid Transporter 1 and 2., PMID:39273030
Polycystic ovarian syndrome (PCOS) and recurrent spontaneous abortion (RSA) are associated with the PI3K-AKT pathway activation., PMID:39253602
Brief Pup Separation in Lactation Confers Stress Resistance with Increased Prolactin and Adult Hippocampal Neurogenesis in Postpartum C57BL/6J Dams., PMID:39235577
Aloperine Inhibits ASFV via Regulating PRLR/JAK2 Signaling Pathway In Vitro., PMID:39201769
Leonurine Exerts Anti-Inflammatory Effects in Lipopolysaccharide (LPS)-Induced Endometritis by Modulating Mouse JAK-STAT/PI3K-Akt/PPAR Signaling Pathways., PMID:39062636
Does the brain make prolactin?, PMID:39041379
[Cuiru Keli Improves Postpartum Hypogalactia in Rats Through Secreted Frizzled-Related Protein 2-Wnt/β-catenin Signaling Pathway]., PMID:38948275
Significance of Duodenal Prolactin Receptor Modulation by Calcium and Vitamin D in Sulpiride-Induced Hyperprolactinemia., PMID:38929559
Inhibition of Prolactin Affects Epididymal Morphology by Decreasing the Secretion of Estradiol in Cashmere Bucks., PMID:38929397
The immunotoxin targeting PRLR increases tamoxifen sensitivity and enhances the efficacy of chemotherapy in breast cancer., PMID:38898487
Membrane Receptor-Mediated Disruption of Cellular Homeostasis: Changes in Intracellular Signaling Pathways Increase the Toxicity of Ochratoxin A., PMID:38880772
The influence of the prolactin/vasoinhibin axis on post-stroke lesion volume, astrogliosis, and survival., PMID:38808481
Prolactin receptor potentiates chemotherapy through miRNAs-induced G6PD/TKT inhibition in pancreatic cancer., PMID:38805171
ABCD4 is associated with mammary gland development in mammals., PMID:38764031
COMT Variants are Associated With Breast and Nipple Pain., PMID:38763257
Loss of PBX1 function in Leydig cells causes testicular dysgenesis and male sterility., PMID:38724675
For research use only. Not for human or drug use.
