Catalog No.
RHA55301
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IF: 1:200-1:1000
Target
hCLOCK, bHLHe8, Class E basic helix-loop-helix protein 8, BHLHE8, Circadian locomoter output cycles protein kaput, CLOCK, KIAA0334
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O15516
Applications
IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2U71
Tissue-origin transcriptomic interactions as indicators of inflammatory aging and aging gene discovery., PMID:40527241
The clock component LHY1b negatively regulates alkaline stress by repressing AOX1-mediated oxidative responses in soybean., PMID:40513111
Light Influences Time-of-Day Differences in the Expression of Clock Genes and Redox Genes Involved in Glutathione Homeostasis in the Lens., PMID:40478559
Genetic determinants of proteomic aging., PMID:40287427
Full-Length Cryptochrome 1 in the Outer Segments of the Retinal Blue Cone Photoreceptors in Humans and Great Apes Suggests a Role Beyond Transcriptional Repression., PMID:40277221
Emergence of a Novel Dengue Virus Serotype-2 Genotype IV Lineage III Strain and Displacement of Dengue Virus Serotype-1 in Central India (2019-2023)., PMID:40006899
Disruption of thyroid-intrinsic clock aggravates experimental autoimmune thyroiditis., PMID:39998446
Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis., PMID:39819503
Chronological Effects of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer., PMID:39777632
Epigenetic Drift Is Involved in the Efficacy of HBV Vaccination., PMID:39771992
Prokineticin 2 protein is diurnally expressed in PER2-containing clock neurons in the mouse suprachiasmatic nucleus., PMID:39755259
Period circadian clock 3 is crucial for regulation of IL-22-producing type 3 innate lymphoid cells by flavonoids from Shen Ling Bai Zhu San to alleviate colitis., PMID:39672410
The circadian clock gene BMAL1 modulates autoimmunity features in lupus., PMID:39664388
Association of the time of day of chemoradiotherapy and durvalumab with tumor control in lung cancer., PMID:39626792
BiP Proteins from Symbiodiniaceae: A "Shocking" Story., PMID:39597516
Genomic instability and genetic heterogeneity in aging: insights from clonal hematopoiesis (CHIP), monoclonal gammopathy (MGUS), and monoclonal B-cell lymphocytosis (MBL)., PMID:39405013
Accelerated Phenotypic Aging Associated With Hepatitis C Infection: Results From the U.S. National Health and Nutrition Examination Surveys 2015-2018., PMID:39297494
Preclinical Evaluation of STI-8811, a Novel Antibody-Drug Conjugate Targeting BCMA for the Treatment of Multiple Myeloma., PMID:39292169
Effect of Urolithin A on the Improvement of Circadian Rhythm Dysregulation in Intestinal Barrier Induced by Inflammation., PMID:39064706
Glycan clock of ageing-analytical precision and time-dependent inter- and i-individual variability., PMID:38877341
Circadian rhythms in the Drosophila eye may regulate adaptation of vision to light intensity., PMID:38872947
Intravitreal Infliximab for the Treatment of Proliferative Vitreoretinopathy (FIXER): A Randomized Controlled Phase II Trial., PMID:38823559
Diurnal control of iron responsive element containing mRNAs through iron regulatory proteins IRP1 and IRP2 is mediated by feeding rhythms., PMID:38773499
The Circadian Clock Component RORA Increases Immunosurveillance in Melanoma by Inhibiting PD-L1 Expression., PMID:38718296
The Benjamin Button effect on stem cells: Reversing the clock on aging immunity., PMID:38701191
Beyond Conventional Therapies: Molecular Dynamics of Alzheimer's Treatment through CLOCK/BMAL1 Interactions., PMID:38509675
Seroprevalence of contagious bovine pleuropneumonia (CBPP) in cattle from Karamoja region, North-eastern Uganda., PMID:38461244
The Trissin/TrissinR signaling pathway in the circadian network regulates evening activity in Drosophila melanogaster under constant dark conditions., PMID:38430699
Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset., PMID:38400792
The rhythms of histones in regeneration: The epigenetic modifications determined by clock genes., PMID:38284199
Mapping of the gene network that regulates glycan clock of ageing., PMID:38149987
Sleep deprivation reduced LPS-induced IgG2b production by up-regulating BMAL1 and CLOCK expression., PMID:38035406
Deficiency of BMAL1 promotes ROS generation and enhances IgE-dependent degranulation in mast cells., PMID:38000295
Reversal of biological age in multiple rat organs by young porcine plasma fraction., PMID:37875652
Comparability of input parameters in the German Retina.net ROP registry and the EU-ROP registry - An exemplary comparison between 2011 and 2021., PMID:37725047
Circadian clock disruption in autoimmune thyroiditis., PMID:37548297
Pigment-dispersing factor is present in circadian clock neurons of pea aphids and may mediate photoperiodic signalling to insulin-producing cells., PMID:37369351
Longitudinal Effects of Herpesviruses on Multiple Cognitive Outcomes in Healthy Elderly Adults., PMID:37334589
The countdown to type 1 diabetes: when, how and why does the clock start?, PMID:37231274
Myeloid Bmal1 deletion suppresses the house dust mite-induced chronic lung allergy., PMID:37170891
Cost-Effectiveness Analysis of Rituximab for Chronic Lymphocytic Leukemia Using a Semi-Markovian Model Approach in R., PMID:36966699
Structural properties and binding mechanism of DNA aptamers sensing saliva melatonin for diagnosis and monitoring of circadian clock and sleep disorders., PMID:36925277
Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition., PMID:36747104
Superior and Anterior Glenoid Labral Tears Are Associated With Increased Neurofilament Concentration., PMID:36637166
Acute hypoxia induced dysregulation of clock-controlled ovary functions., PMID:36620217
Comparison in Retreatments between Bevacizumab and Ranibizumab Intravitreal Injections for Retinopathy of Prematurity: A Multicenter Study., PMID:36396121
In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics., PMID:36366559
TIMELESS is a key gene mediating thrombogenesis in COVID-19 and antiphospholipid syndrome., PMID:36241659
Evidence for overwintering and autochthonous transmission of Usutu virus to wild birds following its redetection in the United Kingdom., PMID:36217722
Time of Day of Vaccination Does Not Associate With SARS-CoV-2 Antibody Titer Following First Dose of mRNA COVID-19 Vaccine., PMID:36154515
For research use only. Not for human or drug use.
