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Recombinant Human GLB1 Protein, N-His

Catalog #:   YHD16301 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P16278
Protein length: Arg68-Thr219
Overview

Catalog No.

YHD16301

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Arg68-Thr219

Predicted molecular weight

20.04 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P16278

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Elastin receptor 1, Beta-galactosidase, GLB1, Acid beta-galactosidase, ELNR1, Lactase

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human GLB1
References

Exploring human plasma proteomic variations in mucolipidosis type IV., PMID:40486934

Integrating Multiomics to Reveal and Validate Key Proteins, Metabolites, and Pathways of ASB14 Affecting Mitochondrial Function in Cardiomyocytes AC16., PMID:40417864

Genotype-Phenotype Relations for the Dystonia-Parkinsonism Genes GLB1, SLC6A3, SLC30A10, SLC39A14, and PLA2G6: MDSGene Systematic Review., PMID:40362326

LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2., PMID:40066518

Evaluation of the Landscape of Pharmacodynamic Biomarkers in GM1 and GM2 Gangliosidosis., PMID:40016926

Identification of a senescence-associated transcriptional program in skeletal muscle of cachectic pancreatic-tumor-bearing mice., PMID:39993009

Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration., PMID:39988732

Integrative transcriptogenomic analyses reveal the regulatory network underlying rice eating and cooking quality and identify a role for alpha-globulin in modulating starch and sucrose metabolism., PMID:39980198

Serum Immune-Response Protein Biomarkers Based on Olink Technology for Diagnosis of Ischemic Stroke., PMID:39900546

Genetic Landscape of Dystonia in Asian Indians., PMID:39749944

Base editing of the GLB1 gene is therapeutic in GM1 gangliosidosis patient-derived cells., PMID:39303319

Circulating ECM proteins decorin and alpha-L-iduronidase differentiate ATTRwt-CM from ATTRwt-negative HFpEF/HFmrEF., PMID:39288026

A novel pulmonary fibrosis NOD/SCID murine model with natural aging., PMID:39285370

Establishment of iPS cell line (SDQLCHi080-A) from a patient with GM1 gangliosidosis due to GLB1 mutation., PMID:39213692

Impaired degradation of PLCG1 by chaperone-mediated autophagy promotes cellular senescence and intervertebral disc degeneration., PMID:39212196

Sequential window acquisition of all theoretical mass spectra (SWATH-MS) as an emerging proteomics approach for the discovery of dark-cutting beef biomarkers., PMID:39096797

Creation of an in vitro model of GM1 gangliosidosis by CRISPR/Cas9 knocking-out the GLB1 gene in SH-SY5Y human neuronal cell line., PMID:39076066

Identification of immunosenescence of unconventional T cells in hepatocellular carcinoma., PMID:39004028

Multiparametric identification of putative senescent cells in skeletal muscle via mass cytometry., PMID:38995093

Breast volume in non-obese females is related to breast adipose cell hypertrophy, inflammation, and COX2 expression., PMID:38967364

ROS-mediated lysosomal membrane permeabilization and autophagy inhibition regulate bleomycin-induced cellular senescence., PMID:38762757

GM1 gangliosidosis type II: Results of a 10-year prospective study., PMID:38641994

Proteomics-Derived Biomarker Panel Facilitates Distinguishing Primary Lung Adenocarcinomas With Intestinal or Mucinous Differentiation From Lung Metastatic Colorectal Cancer., PMID:38608841

Antagonizing Activin A/p15INK4b Signaling as Therapeutic Strategy for Liver Disease., PMID:38607090

Morquio B disease: a case report., PMID:38500590

[Advances in live-imaging aging reporter mice]., PMID:38151347

Lysosomal sialidase NEU1, its intracellular properties, deficiency, and use as a therapeutic agent., PMID:38147151

Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors., PMID:38019733

Dynamics of hemoglobins during nodule development, nitrate response, and dark stress in Lotus japonicus., PMID:37976184

Transcriptomic characterization of Trichoderma harzianum T34 primed tomato plants: assessment of biocontrol agent induced host specific gene expression and plant growth promotion., PMID:37940862

Data-Independent Acquisition Mass Spectrometry Analysis of FFPE Rectal Cancer Samples Offers In-Depth Proteomics Characterization of the Response to Neoadjuvant Chemoradiotherapy., PMID:37895091

The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn2+ trafficking., PMID:37876250

Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 gangliosidosis., PMID:37871851

Involvement of the aryl hydrocarbon receptor (AhR) in the mechanism of action of elastin-derived peptide (VGVAPG) and its impact on neurosteroidogenesis., PMID:37769996

Enhanced Efficiency of the Basal and Induced Apoptosis Process in Mucopolysaccharidosis IVA and IVB Human Fibroblasts., PMID:37762422

The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe., PMID:37724332

Effects of Fisetin Treatment on Cellular Senescence of Various Tissues and Organs of Old Sheep., PMID:37627641

Nitric Oxide and Globin Glb1 Regulate Fusarium oxysporum Infection of Arabidopsis thaliana., PMID:37507861

Study on the Mechanism of Naoxintong in the Treatment of Cerebral Ischemia-Reperfusion Injury Based on a Multiomics Method., PMID:37261991

Metabolic Cardiomyopathies and Cardiac Defects in Inherited Disorders of Carbohydrate Metabolism: A Systematic Review., PMID:37239976

Prediction of active marker of seabuckthorn polysaccharides for prevention and treatment of cervical cancer and mechanism study., PMID:36845055

p53 Regulates Mitochondrial Dynamics in Vascular Smooth Muscle Cell Calcification., PMID:36675156

Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient., PMID:36629845

Dapagliflozin Prevents High-Glucose-Induced Cellular Senescence in Renal Tubular Epithelial Cells., PMID:36555751

The lncRNA NEAT1 Mediates Neuronal Cell Autophagy and Related Protein Expression After Cerebral Ischemia‒Reperfusion Injury., PMID:36512294

OPAQUE3, encoding a transmembrane bZIP transcription factor, regulates endosperm storage protein and starch biosynthesis in rice., PMID:36258666

Mutations, Genes, and Phenotypes Related to Movement Disorders and Ataxias., PMID:36233161

Overexpression of a soybean Globin (GmGlb1-1) gene reduces plant susceptibility to Meloidogyne incognita., PMID:36112244

PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE., PMID:35887093

Synthesis of a New β-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis., PMID:35807262

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

Contact Information

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For research use only. Not for human or drug use.

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Recombinant Human GLB1 Protein, N-His [YHD16301]
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