Catalog No.
RHA11104
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
Putative MCP-1 chemokine receptor, CKRX, CCRL2, CRAM, C-C chemokine receptor-like 2, Chemokine receptor CCR11, Chemokine receptor X, CCR6, CCR11, HCR
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O00421
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2T76
Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model., PMID:40181978
Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model., PMID:39386470
Chemerin abundance in egg white and its expression with receptors in extra-embryonic annexes of Pekin ducks: implications for embryo development., PMID:39002372
Expression of chemerin and its receptors in extra-embryonic annexes and role of chemerin and its GPR1 receptor in embryo development in layer and broiler hens., PMID:38118220
Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function., PMID:36662882
Chemerin is secreted by the chicken oviduct, accumulates in egg albumen and could promote embryo development., PMID:35644891
Absence of the Non-Signalling Chemerin Receptor CCRL2 Exacerbates Acute Inflammatory Responses In Vivo., PMID:29209334
CHEMERIN (RARRES2) decreases in vitro granulosa cell steroidogenesis and blocks oocyte meiotic progression in bovine species., PMID:24671882
Complementary populations of human adipose CD34+ progenitor cells promote growth, angiogenesis, and metastasis of breast cancer., PMID:23918796
Role of the atypical chemoattractant receptor CRAM in regulating CCL19 induced CCR7 responses in B-cell chronic lymphocytic leukemia., PMID:21092185
CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B., PMID:20002784
Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis., PMID:18794339
For research use only. Not for human or drug use.
