Catalog No.
RHA05801
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Applications
ELISA, FCM, IHC
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000 |
Target
Hyaluronate synthase 3, Hyaluronan synthase 3, HAS3, Hyaluronic acid synthase 3, HA synthase 3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O00219
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2T25
Note
For research use only.
Expression of integrin subunits in the human infant breast correlates with morphogenesis and differentiation., PMID:7674085
Molecular cloning, expression, and characterization of the authentic hyaluronan synthase from group C Streptococcus equisimilis., PMID:9405467
Expression of human hyaluronan synthases in response to external stimuli., PMID:10794710
Reticular erythematous mucinosis syndrome with an infiltration of factor XIIIa+ and hyaluronan synthase 2+ dermal dendrocytes., PMID:11453924
Expression of hyaluronan synthases and CD44 messenger RNAs in porcine cumulus-oocyte complexes during in vitro maturation., PMID:11870078
Hyaluronan facilitates invasion of colon carcinoma cells in vitro via interaction with CD44., PMID:15231668
Hyaluronan synthase expression in ovarian cancer., PMID:15375493
Hyaluronan synthase expression in pleural malignant mesotheliomas., PMID:15731923
Role of hyaluronan and hyaluronan synthase in endometrial cancer., PMID:15870928
Expression patterns of hyaluronan, hyaluronan synthases and hyaluronidases indicate a role for hyaluronan in the progression of endometrial cancer., PMID:15936804
Elevated level of ambient glucose stimulates the synthesis of high-molecular-weight hyaluronic acid by human mesangial cells. The involvement of transforming growth factor beta1 and its activation by thrombospondin-1., PMID:16733556
Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells., PMID:16900089
Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB., PMID:17324121
An enzyme capture assay for analysis of active hyaluronan synthases., PMID:17904513
Hyaluronan-CD44-ERK1/2 regulate human aortic smooth muscle cell motility during aging., PMID:18077444
Up-regulation of hyaluronan synthase genes in cultured human epidermal keratinocytes by UVB irradiation., PMID:18158910
Expression of hyaluronan synthase 1 and distribution of hyaluronan during follicular atresia in pig ovaries., PMID:18923162
Effects of thyrotropin and thyrotropin-receptor-stimulating Graves' disease immunoglobulin G on cyclic adenosine monophosphate and hyaluronan production in nondifferentiated orbital fibroblasts of Graves' ophthalmopathy patients., PMID:20384487
Expression of hyaluronan synthase 3 in deformed human temporomandibular joint discs: in vivo and in vitro studies., PMID:21263749
Therapeutic potential of hyaluronan oligosaccharides for bone metastasis of breast cancer., PMID:21913222
Cell surface expression of hyaluronan on human ovarian cancer cells inversely correlates with their adhesion to peritoneal mesothelial cells., PMID:22392500
Critical role of hyaluronidase-2 during preimplantation embryo development., PMID:23625939
Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells., PMID:23979132
Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes., PMID:24057227
Hyaluronan synthase 1 (HAS1) produces a cytokine-and glucose-inducible, CD44-dependent cell surface coat., PMID:24099991
Hyaluronan synthases (HAS1-3) in stromal and malignant cells correlate with breast cancer grade and predict patient survival., PMID:24337597
Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3., PMID:25795779
Cell protrusions induced by hyaluronan synthase 3 (HAS3) resemble mesothelial microvilli and share cytoskeletal features of filopodia., PMID:26162854
The reciprocal association between mammographic breast density, hyaluronan synthesis and patient outcome., PMID:26362804
Distribution and characteristics of slow-cycling cells in rat vocal folds., PMID:26845229
In silico analysis of candidate proteins sharing homology with Streptococcus agalactiae proteins and their role in male infertility., PMID:27802063
4-Methylumbelliferone Suppresses Hyaluronan Synthesis and Tumor Progression in SCID Mice Intra-abdominally Inoculated With Pancreatic Cancer Cells., PMID:27846148
Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer., PMID:28107185
Tau Pathology Promotes the Reorganization of the Extracellular Matrix and Inhibits the Formation of Perineuronal Nets by Regulating the Expression and the Distribution of Hyaluronic Acid Synthases., PMID:28234253
Hyaluronan synthase 3 promotes plaque inflammation and atheroprogression., PMID:28987865
Hyaluronan-CD44/RHAMM interaction-dependent cell proliferation and survival in lung cancer cells., PMID:30365189
Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases., PMID:32047499
Effects of Apigenin on RBL-2H3, RAW264.7, and HaCaT Cells: Anti-Allergic, Anti-Inflammatory, and Skin-Protective Activities., PMID:32610574
Effect of ligand-receptor interaction of osteopontin-CD44 on the expression of hyaluronic acid in human knee osteoarthritic chondrocytes in vitro., PMID:33051414
Modulation of hyaluronan synthases and involvement of T cell-derived hyaluronan in autoimmune responses to transplanted islets., PMID:33718858
Endothelial Hyaluronan Synthase 3 Augments Postischemic Arteriogenesis Through CD44/eNOS Signaling., PMID:34380333
Cell-Type-Specific Expression of Hyaluronan Synthases HAS2 and HAS3 Promotes Goblet Cell Hyperplasia in Allergic Airway Inflammation., PMID:35679095
For research use only. Not for human or drug use.
