Catalog No.
VMG33801
Species reactivity
Mouse
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
CD161a, NKR-P1.7, Ly-55A, Lymphocyte antigen 55A, NKR-P1 2, Killer cell lectin-like receptor subfamily B member 1A, CD161 antigen-like family member A, Ly55, NKR-P1A, Natural killer cell surface protein P1-2, Nkrp1a, Klrb1a, Ly55a
Concentration
1 mg/ml
Endotoxin level
< 1 EU/mg as determined by LAL test.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
ELISA, FCM, In vivo NK cell Depletion
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
PK136
Dual therapy for amanita phalloides-induced acute liver failure in mice: A combination of etanercept and alpha-1 antitrypsin., PMID:40398510
Upregulation of Fcγ Receptor IV on Activated Monocytes and Macrophages Causes Nonspecific Binding of the PK136 Anti-NK1.1 Antibody in Murine Models of Toll-Like Receptor-Induced Inflammation., PMID:40275544
Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis., PMID:40173259
Group 1 innate lymphoid cells protect liver transplants from ischemia-reperfusion injury via an interferon gamma-mediated pathway., PMID:39736469
Magnesium-Phenolic Nanoeditor Refining Gliomatous T Cells for Metalloimmunotherapy., PMID:39701951
Characterization of anti-asialo-GM1 monoclonal antibody., PMID:39693935
NK cells contribute to the resolution of experimental malaria-associated acute respiratory distress syndrome after antimalarial treatment., PMID:39355242
Synergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3 + NK1.1 + cell recruitment secondary to induction of cytokines from tumor cells., PMID:38790057
Early infiltrating NKT lymphocytes attenuate bone regeneration through secretion of CXCL2., PMID:38758783
CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs., PMID:38724465
Aspecific binding of anti-NK1.1 antibodies on myeloid cells in an experimental model for malaria-associated acute respiratory distress syndrome., PMID:38637828
Ozanimod-mediated remission in experimental autoimmune encephalomyelitis is associated with enhanced activity of CNS CD27low/- NK cell subset., PMID:38533505
The Combination of Anti-CD47 Antibody with CTLA4 Blockade Enhances Anti-Tumor Immunity in Non-Small Cell Lung Cancer via Normalization of Tumor Vasculature and Reprogramming of the Immune Microenvironment., PMID:38398223
Evaluation of the TLR3 involvement during Schistosoma japonicum-induced pathology., PMID:38172683
Fibroblast growth factor inhibition by molecular-targeted agents mitigates immunosuppressive tissue microenvironment in hepatocellular carcinoma., PMID:37864726
Flow cytometric analysis of innate lymphoid cells: challenges and solutions., PMID:37809100
ILC1-derived IFN-γ regulates macrophage activation in colon cancer., PMID:37679802
Inhibition of NK1.1 signaling attenuates pressure overload-induced heart failure, and consequent pulmonary inflammation and remodeling., PMID:37554327
Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584., PMID:36993977
Inhibiting DNA methylation and RNA editing upregulates immunogenic RNA to transform the tumor microenvironment and prolong survival in ovarian cancer., PMID:36343976
Liposomes Bearing Non-Bilayer Phospholipid Arrangements Induce Specific IgG Anti-Lipid Antibodies by Activating NK1.1+, CD4+ T Cells in Mice., PMID:35877846
Oxaliplatin facilitates tumor-infiltration of T cells and natural-killer cells for enhanced tumor immunotherapy in lung cancer model., PMID:34561996
Eubacterium rectale Attenuates HSV-1 Induced Systemic Inflammation in Mice by Inhibiting CD83., PMID:34531862
The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides., PMID:34519839
Natural Killer Cells Are Present in Rag1-/- Mice and Promote Tissue Damage During the Acute Phase of Ischemic Stroke., PMID:34105078
IL-2Rβγ signalling in lymphocytes promotes systemic inflammation and reduces plasma cholesterol in atherosclerotic mice., PMID:33945906
Human hydatid cyst fluid-induced therapeutic anti-cancer immune responses via NK1.1+ cell activation in mice., PMID:33944981
17β-Estradiol Is Involved in the Sexual Dimorphism of the Immune Response to Malaria., PMID:33841336
NK1.1- natural killer T cells upregulate interleukin-17 expression in experimental lupus nephritis., PMID:33719574
Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma., PMID:33520112
Baculovirus AcMNPV induces type I interferons and NK/NKT cells-mediated protection against foot-and-mouth disease virus in mice., PMID:32574690
Immunological Analysis of the Hepatitis B Virus "a" Determinant Displayed on Chimeric Virus-Like Particles of Macrobrachium rosenbergii Nodavirus Capsid Protein Produced in Sf9 Cells., PMID:32512923
Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model., PMID:32503894
Innate Lymphoid Cells Are Required for Endometrial Resistance to Chlamydia trachomatis Infection., PMID:32341118
The Toll-Like Receptor 3 Agonist Polyriboinosinic Polyribocytidylic Acid Increases the Numbers of NK Cells with Distinct Phenotype in the Liver of B6 Mice., PMID:32211442
Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer., PMID:32179091
Effects of maternal L-proline supplementation on inflammatory cytokines at the placenta and fetus interface of mice., PMID:32170468
NK Cells Regulate CD8+ T Cell Mediated Autoimmunity., PMID:32117809
Evasion of Innate Lymphoid Cell-Regulated Gamma Interferon Responses by Chlamydia muridarum To Achieve Long-Lasting Colonization in Mouse Colon., PMID:31818961
Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats., PMID:31784606
Personalized inherent randomness of the immune system is manifested by an individualized response to immune triggers and immunomodulatory therapies: a novel platform for designing personalized immunotherapies., PMID:31754971
Lyophilizable and Multifaceted Toll-like Receptor 7/8 Agonist-Loaded Nanoemulsion for the Reprogramming of Tumor Microenvironments and Enhanced Cancer Immunotherapy., PMID:31589013
Inhibition of CD147 Attenuates Stroke-Associated Pneumonia Through Modulating Lung Immune Response in Mice., PMID:31447768
Increased lymphocyte activation and atherosclerosis in CD47-deficient mice., PMID:31337788
Tissue-resident natural killer cells exacerbate tubulointerstitial fibrosis by activating transglutaminase 2 and syndecan-4 in a model of aristolochic acid-induced nephropathy., PMID:31072444
Studies on B Cells in the Fruit-Eating Black Flying Fox (Pteropus alecto)., PMID:30930908
The TLR3 Agonist Poly Inosinic:Cytidylic Acid Significantly Augments the Therapeutic Activity of an Anti-CD7 Immunotoxin for Human T-cell Leukaemia., PMID:30781517
Human gingiva-derived mesenchymal stem cells alleviate inflammatory bowel disease via IL-10 signalling-dependent modulation of immune cells., PMID:30664802
CD83+ CCR7+ NK cells induced by interleukin 18 by dendritic cells promote experimental autoimmune uveitis., PMID:30548211
In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection., PMID:30503624