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InVivoMAb Anti-Mouse NK1.1 Antibody (PK136)

Catalog #:   VMG33801 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, FCM, In vivo NK cell Depletion
Overview

Catalog No.

VMG33801

Species reactivity

Mouse

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

CD161a, NKR-P1.7, Ly-55A, Lymphocyte antigen 55A, NKR-P1 2, Killer cell lectin-like receptor subfamily B member 1A, CD161 antigen-like family member A, Ly55, NKR-P1A, Natural killer cell surface protein P1-2, Nkrp1a, Klrb1a, Ly55a

Concentration

1 mg/ml

Endotoxin level

< 1 EU/mg as determined by LAL test.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

ELISA, FCM, In vivo NK cell Depletion

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

PK136

Data Image
References

Dual therapy for amanita phalloides-induced acute liver failure in mice: A combination of etanercept and alpha-1 antitrypsin., PMID:40398510

Upregulation of Fcγ Receptor IV on Activated Monocytes and Macrophages Causes Nonspecific Binding of the PK136 Anti-NK1.1 Antibody in Murine Models of Toll-Like Receptor-Induced Inflammation., PMID:40275544

Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis., PMID:40173259

Group 1 innate lymphoid cells protect liver transplants from ischemia-reperfusion injury via an interferon gamma-mediated pathway., PMID:39736469

Magnesium-Phenolic Nanoeditor Refining Gliomatous T Cells for Metalloimmunotherapy., PMID:39701951

Characterization of anti-asialo-GM1 monoclonal antibody., PMID:39693935

NK cells contribute to the resolution of experimental malaria-associated acute respiratory distress syndrome after antimalarial treatment., PMID:39355242

Synergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3 + NK1.1 + cell recruitment secondary to induction of cytokines from tumor cells., PMID:38790057

Early infiltrating NKT lymphocytes attenuate bone regeneration through secretion of CXCL2., PMID:38758783

CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs., PMID:38724465

Aspecific binding of anti-NK1.1 antibodies on myeloid cells in an experimental model for malaria-associated acute respiratory distress syndrome., PMID:38637828

Ozanimod-mediated remission in experimental autoimmune encephalomyelitis is associated with enhanced activity of CNS CD27low/- NK cell subset., PMID:38533505

The Combination of Anti-CD47 Antibody with CTLA4 Blockade Enhances Anti-Tumor Immunity in Non-Small Cell Lung Cancer via Normalization of Tumor Vasculature and Reprogramming of the Immune Microenvironment., PMID:38398223

Evaluation of the TLR3 involvement during Schistosoma japonicum-induced pathology., PMID:38172683

Fibroblast growth factor inhibition by molecular-targeted agents mitigates immunosuppressive tissue microenvironment in hepatocellular carcinoma., PMID:37864726

Flow cytometric analysis of innate lymphoid cells: challenges and solutions., PMID:37809100

ILC1-derived IFN-γ regulates macrophage activation in colon cancer., PMID:37679802

Inhibition of NK1.1 signaling attenuates pressure overload-induced heart failure, and consequent pulmonary inflammation and remodeling., PMID:37554327

Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584., PMID:36993977

Inhibiting DNA methylation and RNA editing upregulates immunogenic RNA to transform the tumor microenvironment and prolong survival in ovarian cancer., PMID:36343976

Liposomes Bearing Non-Bilayer Phospholipid Arrangements Induce Specific IgG Anti-Lipid Antibodies by Activating NK1.1+, CD4+ T Cells in Mice., PMID:35877846

Oxaliplatin facilitates tumor-infiltration of T cells and natural-killer cells for enhanced tumor immunotherapy in lung cancer model., PMID:34561996

Eubacterium rectale Attenuates HSV-1 Induced Systemic Inflammation in Mice by Inhibiting CD83., PMID:34531862

The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides., PMID:34519839

Natural Killer Cells Are Present in Rag1-/- Mice and Promote Tissue Damage During the Acute Phase of Ischemic Stroke., PMID:34105078

IL-2Rβγ signalling in lymphocytes promotes systemic inflammation and reduces plasma cholesterol in atherosclerotic mice., PMID:33945906

Human hydatid cyst fluid-induced therapeutic anti-cancer immune responses via NK1.1+ cell activation in mice., PMID:33944981

17β-Estradiol Is Involved in the Sexual Dimorphism of the Immune Response to Malaria., PMID:33841336

NK1.1- natural killer T cells upregulate interleukin-17 expression in experimental lupus nephritis., PMID:33719574

Improved therapeutic efficacy of unmodified anti-tumor antibodies by immune checkpoint blockade and kinase targeted therapy in mouse models of melanoma., PMID:33520112

Baculovirus AcMNPV induces type I interferons and NK/NKT cells-mediated protection against foot-and-mouth disease virus in mice., PMID:32574690

Immunological Analysis of the Hepatitis B Virus "a" Determinant Displayed on Chimeric Virus-Like Particles of Macrobrachium rosenbergii Nodavirus Capsid Protein Produced in Sf9 Cells., PMID:32512923

Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model., PMID:32503894

Innate Lymphoid Cells Are Required for Endometrial Resistance to Chlamydia trachomatis Infection., PMID:32341118

The Toll-Like Receptor 3 Agonist Polyriboinosinic Polyribocytidylic Acid Increases the Numbers of NK Cells with Distinct Phenotype in the Liver of B6 Mice., PMID:32211442

Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer., PMID:32179091

Effects of maternal L-proline supplementation on inflammatory cytokines at the placenta and fetus interface of mice., PMID:32170468

NK Cells Regulate CD8+ T Cell Mediated Autoimmunity., PMID:32117809

Evasion of Innate Lymphoid Cell-Regulated Gamma Interferon Responses by Chlamydia muridarum To Achieve Long-Lasting Colonization in Mouse Colon., PMID:31818961

Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats., PMID:31784606

Personalized inherent randomness of the immune system is manifested by an individualized response to immune triggers and immunomodulatory therapies: a novel platform for designing personalized immunotherapies., PMID:31754971

Lyophilizable and Multifaceted Toll-like Receptor 7/8 Agonist-Loaded Nanoemulsion for the Reprogramming of Tumor Microenvironments and Enhanced Cancer Immunotherapy., PMID:31589013

Inhibition of CD147 Attenuates Stroke-Associated Pneumonia Through Modulating Lung Immune Response in Mice., PMID:31447768

Increased lymphocyte activation and atherosclerosis in CD47-deficient mice., PMID:31337788

Tissue-resident natural killer cells exacerbate tubulointerstitial fibrosis by activating transglutaminase 2 and syndecan-4 in a model of aristolochic acid-induced nephropathy., PMID:31072444

Studies on B Cells in the Fruit-Eating Black Flying Fox (Pteropus alecto)., PMID:30930908

The TLR3 Agonist Poly Inosinic:Cytidylic Acid Significantly Augments the Therapeutic Activity of an Anti-CD7 Immunotoxin for Human T-cell Leukaemia., PMID:30781517

Human gingiva-derived mesenchymal stem cells alleviate inflammatory bowel disease via IL-10 signalling-dependent modulation of immune cells., PMID:30664802

CD83+ CCR7+ NK cells induced by interleukin 18 by dendritic cells promote experimental autoimmune uveitis., PMID:30548211

In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection., PMID:30503624

Datasheet
$ 302
Product specifications
100 μg 302 1 mg 1204

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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InVivoMAb Anti-Mouse NK1.1 Antibody (PK136) [VMG33801]
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