Catalog No.
YHD09901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro21-Ser295
Predicted molecular weight
31.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15289
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cerebroside-sulfatase, ASA, Arylsulfatase A, ARSA
Convergent Pathways Identified for Cannabis Use Disorder Across Diverse Ancestry Populations., PMID:40166572
Purifying selection of the lysosomal enzymes arylsulfatase A and beta-galactocerebrosidase and their evolutionary impact on myelin integrity., PMID:40054667
An augmented transformer model trained on protein family specific variant data leads to improved prediction of variants of uncertain significance., PMID:39869148
Relative Frequency of Metachromatic Leukodystrophy in Egypt: A Reference Laboratory Report., PMID:39736016
Multi-Omics Approach Reveals Genes and Pathways Affected in Miller-Dieker Syndrome., PMID:39508990
Nanoparticles encapsulating phosphatidylinositol derivatives promote neuroprotection and functional improvement in preclinical models of ALS via a long-lasting activation of TRPML1 lysosomal channel., PMID:39491634
ARSA Variant Associated With Late Infantile Metachromatic Leukodystrophy and Carrier Rate in Individuals of Ashkenazi Jewish Ancestry., PMID:39473378
Bone marrow transplantation increases sulfatase activity in somatic tissues in a multiple sulfatase deficiency mouse model., PMID:39448727
QAFI: a novel method for quantitative estimation of missense variant impact using protein-specific predictors and ensemble learning., PMID:39048855
Exploring the effect of disease causing mutations in metal binding sites of human ARSA in metachromatic leukodystrophy., PMID:38960474
Lentivirus-modified hematopoietic stem cell gene therapy for advanced symptomatic juvenile metachromatic leukodystrophy: a long-term follow-up pilot study., PMID:38916435
Genomic Characterization and Phylogenetic Analysis of Linezolid-Resistant Enterococcus from the Nostrils of Healthy Hosts Identifies Zoonotic Transmission., PMID:38877167
A distinct dimer configuration of a diatom Get3 forming a tetrameric complex with its tail-anchored membrane cargo., PMID:38867239
Biochemical and molecular analysis of pediatric patients with metachromatic leukodystrophy in South China: functional characterization of five novel ARSA variants., PMID:38775997
Lysosomal Channels as New Molecular Targets in the Pharmacological Therapy of Neurodegenerative Diseases via Autophagy Regulation., PMID:38766825
Joint-tissue integrative analysis identifies high-risk genes for Parkinson's disease., PMID:38576865
In Silico Structural Modeling and Binding Site Analysis of Cerebroside Sulfotransferase (CST): A Therapeutic Target for Developing Substrate Reduction Therapy for Metachromatic Leukodystrophy., PMID:38463293
Biotransformation of Pb and As from sewage sludge and food waste by black soldier fly larvae: Migration mechanism of bacterial community and metalloregulatory protein scales., PMID:38447376
Autophagy Proteins and clinical data reveal the prognosis of polycystic ovary syndrome., PMID:38383330
Identification and structural characterization of a pathogenic ARSA missense variant in two consanguineous families from Jammu and Kashmir (India) with late infantile metachromatic leukodystrophy., PMID:38153581
Microbiome and plant cell transformation trigger insect gall induction in cassava., PMID:38126017
A Phase I Study of the CDK4/6 Inhibitor Palbociclib in Combination with Cetuximab and Radiotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma., PMID:37982827
Identification of the genetic basis of pediatric neurogenetic disorders at a tertiary referral hospital in Indonesia: Contribution of whole exome sequencing., PMID:37878632
Expanding causal genes for Parkinson's disease via multi-omics analysis., PMID:37865667
Whole-genome sequencing analysis of suicide deaths integrating brain-regulatory eQTLs data to identify risk loci and genes., PMID:37794117
Identification of a Novel ARSA Gene Mutation Through High-Throughput Molecular Diagnosis Method in Two Girls with Late Infantile Metachromatic Leukodystrophy., PMID:37682448
High genetic heterogeneity of leukodystrophies in Iranian children: the first report of Iranian Leukodystrophy Registry., PMID:37597066
Rhizospheric bacteria: the key to sustainable heavy metal detoxification strategies., PMID:37555069
Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient phenotype matrix., PMID:37480112
Parkinson's disease - genetic cause., PMID:37366140
Whole exome sequencing identified five novel variants in CNTN2, CARS2, ARSA, and CLCN4 leading to epilepsy in consanguineous families., PMID:37359369
Safety and Efficacy of Intravenous and Intrathecal Delivery of AAV9-Mediated ARSA in Minipigs., PMID:37298156
Revealing the roles of glycosphingolipid metabolism pathway in the development of keloid: a conjoint analysis of single-cell and machine learning., PMID:37168863
Novel in-frame duplication variant characterization in late infantile metachromatic leukodystrophy using whole-exome sequencing and molecular dynamics simulation., PMID:36848337
Serum proteomics profiling identifies a preliminary signature for the diagnosis of early-stage lung cancer., PMID:36645712
Clinical correlations with EGFR circulating tumor DNA testing in all-stage lung adenocarcinoma., PMID:36530081
Predicting clinical phenotypes of metachromatic leukodystrophy based on the arylsulfatase A activity and the ARSA genotype? - Chances and challenges., PMID:36240581
Phylogenetic analysis and characterization of arsenic (As) transforming bacterial marker proteins following isolation of As-tolerant indigenous bacteria., PMID:36190579
[Analysis of genetic variant in a patient with juvenile meterochromic leukodystrophy]., PMID:36184090
The lysosomal proteome of senescent cells contributes to the senescence secretome., PMID:36087066
Genome mining, phylogenetic, and functional analysis of arsenic (As) resistance operons in Bacillus strains, isolated from As-rich hot spring microbial mats., PMID:36027845
Evaluation of bovine uterine gland functions in 2D and 3D culture system., PMID:35644574
Proteome profiling reveals changes in energy metabolism, transport and antioxidation during drought stress in Nostoc flagelliforme., PMID:35365086
Identification and Genome Analysis of an Arsenic-Metabolizing Strain of Citrobacter youngae IITK SM2 in Middle Indo-Gangetic Plain Groundwater., PMID:35309170
Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control., PMID:35273160
TLR4 and pSTAT3 Expression on Circulating Tumor Cells (CTCs) and Immune Cells in the Peripheral Blood of Breast Cancer Patients: Prognostic Implications., PMID:35205801
Pyrazine yield and functional properties of rice bran protein hydrolysate formed by the Maillard reaction at varying pH., PMID:35185198
Bioinformatic Approach to Unveil Key Differentially Expressed Proteins in Human Sperm After Slow and Rapid Cryopreservation., PMID:35145967
Sb(III) resistance mechanism and oxidation characteristics of Klebsiella aerogenes X., PMID:34971630
Proteomics study reveals the molecular mechanisms underlying cryotolerance induced by mild sublethal stress in human sperm., PMID:34729646
For research use only. Not for human or drug use.
