The importance of paying attention to the role of lipid-lowering drugs in controlling dengue virus infection., PMID:39702248
A CRISPR-HITI strategy approach to improve CHO cell viability by modifying the 3'UTR of Caspase 8 Associated Protein 2., PMID:39744509
Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies., PMID:39760073
Sialoadhesin-dependent susceptibility and replication of porcine reproductive and respiratory syndrome viruses in CD163-expressing cells., PMID:39776598
Comprehensive genome-scale CRISPR knockout screening of CHO cells., PMID:39814846
Transferrin-binding domain inserted-adenovirus hexon engineering enables systemic immune evasion and intratumoral T-cell activation., PMID:39816694
Discovery of a heparan sulfate binding domain in monkeypox virus H3 as an anti-poxviral drug target combining AI and MD simulations., PMID:39817728
Involvement of MID1-COMPLEMENTING ACTIVITY 1 encoding a mechanosensitive ion channel in prehaustorium development of the stem parasitic plant Cuscuta campestris., PMID:39821429
Proteomics Reveals Distinctive Host Cell Protein Expression Patterns in Fed-Batch and Perfusion Cell Culture Processes., PMID:39834099
Development of an attenuated glutamine synthetase (GS) selection system for the stable expression of tissue plasminogen activator in CHO-K1 cells., PMID:39838843
Assessing the Adjuvant Potential of Chinese Hamster Ovary Host Cell Proteins Using an In Vitro Dendritic Cell Assay., PMID:39930890
Oxidative High Mobility Group Box-1 Accelerates Mitochondrial Transfer from Mesenchymal Stem Cells to Colorectal Cancer Cells Providing Cancer Cell Stemness., PMID:39940960
Extracorporeal photopheresis induces the release of anti-inflammatory fatty acids and oxylipins and suppresses pro-inflammatory sphingosine-1-phosphate., PMID:39945859
Syncytial therapeutics: Receptor-specific and direct-to-cytosol biologic drug delivery mediated by measles fusion complex., PMID:39956393
Barriers Composed of tRNA Genes Can Complement the Benefits of a Ubiquitous Chromatin Opening Element to Enhance Transgene Expression., PMID:39956936
Studying host cell protein based on 2D nano-LC-MS/MS: comparison between the removal and the reservation of the main antibody components., PMID:39964430
SIRT6 Ameliorates Cancer Cachexia-Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice., PMID:39971710
Systems Biology of Recombinant 2G12 and 353/11 mAb Production in CHO-K1 Cell Lines at Phosphoproteome Level., PMID:39982319
Cryo-EM structure of the bacterial intramembrane metalloprotease RseP in the substrate-bound state., PMID:40009668
MAT2A Knockdown Enhances Recombinant Protein Expression in Transgenic CHO Cells Through Regulation of Cell Cycle., PMID:40011400
Pilin regions that select for the small RNA phages in Pseudomonas aeruginosa type IV pilus., PMID:40013800
Cas9-mediated gene-editing frequency in microalgae is doubled by harnessing the interaction between importin α and phytopathogenic NLSs., PMID:40030016
Caspase cleavage of influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production., PMID:40033051
Microbiome-emitted scents activate olfactory neuron-independent airway-gut-brain axis to promote host growth in Drosophila., PMID:40038269
A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response., PMID:40073153
Tripartite motif 22 (TRIM22) downregulates TLR3-induced CCL5 expression in human renal proximal tubular epithelial cells., PMID:40080304
Role of Bean Yellow Mosaic Virus P1 and HC-Pro in Enhancing Gene Expression and Suppressing RNA Silencing in Nicotiana benthamiana., PMID:40141816
Assembly Formation of P65 Protein, Featured by an Intrinsically Disordered Region Involved in Gliding Machinery of Mycoplasma pneumoniae., PMID:40149965
Rapid Recovery From SARS-CoV-2 Infection Among Immunocompromised Children Despite Limited Neutralizing Antibody Response: A Virologic and Sero-Immunologic Analysis of a Single-Center Cohort., PMID:40165575
Comparative Analysis of Codon Optimization Tools: Advancing toward a Multi-Criteria Framework for Synthetic Gene Design., PMID:40223268
CD155 blockade enhances allogeneic natural killer cell-mediated antitumor response against osteosarcoma., PMID:40234092
Discovery of Chemical Tools for Polysorbate-Degradative Enzyme Control in the Biopharmaceutical Upstream Process via Multi-Omic Profiling of Host Cell Clones., PMID:40249937
Implementation of a high throughput automated platform for residual DNA quantitation., PMID:40273126
Abundant β-Defensin Copy Number Variations in Pigs., PMID:40282390
Ephrin B1 and B2 Mediate Cedar Virus Entry into Egyptian Fruit Bat Cells., PMID:40285015
Differential polyamine metabolism in CHO cell lines: Insights into cell growth and antibody quality., PMID:40287131
m6A modification profiles of the CHO cells with differential recombinant protein expression using MeRIP-seq/RNA-seq., PMID:40288720
Multi-component behavior of host-cell protein- and antibody-containing heteroaggregates in protein A chromatography., PMID:40311270
Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis., PMID:40327404
Streamlined purification of recombinant Alpha-1 antitrypsin from CHO cell culture using integrated chromatography within a single unit operation., PMID:40367846
Utilizing Stable Gene-Edited Knockout Pools for Genetic Screening and Engineering in Chinese Hamster Ovary Cells., PMID:40376717
Phase 2 trial of cyclosporine-A, mycophenolate mofetil, and tocilizumab GVHD prophylaxis in cord blood transplantation., PMID:40423982
Production of multi-subunit proteins in CHO cells by transposase-mediated integration of subunit-splitting vectors., PMID:40425682
PAT-on-a-chip: Miniaturization of analytical assays towards data-driven bioprocess development and optimization., PMID:40435762
Without a trace: multiple knockout of CHO host cell hydrolases to prevent polysorbate degradation in biologics., PMID:40441922
Isolation, characterization, and expression of the Montivipera raddei (Caucasus viper) venom metalloprotease-like protein., PMID:40444163
Deep learning-guided structural analysis of a novel bacteriophage KPP105 against multidrug-resistant Klebsiella pneumoniae., PMID:40470315
From Discovery to Delivery: A Rapid and Targeted Proteomics Workflow for Monitoring Chinese Hamster Ovary Biomanufacturing., PMID:40480342
CAP Peptides Artificially Induce Insect-gall-like Growth in Different Plant Species., PMID:40488419
SPINT1 Expressed in Epithelial Cells of Choroid Plexus in Human and Mouse Brains., PMID:40507942