Catalog No.
YHD08501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile110-Ser417
Predicted molecular weight
62.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15088
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CPA3, MC-CPA, Mast cell carboxypeptidase A, Carboxypeptidase A3
Effects of C3aR activated mast cells in eosinophilic esophagitis., PMID:40502038
A Comprehensive Analysis of Chemical Composition and Anti-Inflammatory Effects of Cassava Leaf Extracts in Two Varieties in Manihot esculenta Crantz., PMID:40362388
Mast cell activation signature as a potential biomarker in COVID-19., PMID:40250770
Co-occurrence of parkinson disease and multiple sclerosis - a critical note., PMID:40214766
Apigenin ameliorates inflamed ulcerative colitis by regulating mast cell degranulation via the PAMP-MRGPRX2 feedback loop., PMID:40054174
Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC., PMID:39840068
Identifying potential active ingredients from pomegranate in treating anemia: CPA3 and SOX4 are key proteins., PMID:39608521
Mast Cell Carboxypeptidase A3 Is Associated with Pulmonary Fibrosis Secondary to COVID-19., PMID:39596322
Mast cell MrgprB2 in neuroimmune interaction in IgE-mediated airway inflammation and its modulation by β-arrestin2., PMID:39483467
Neuroplasticity and neuroimmune interactions in fatal asthma., PMID:39484998
No signs of mast cell involvement in long-COVID: A case-control study., PMID:39285602
The Contribution of Mast Cells to the Regulation of Elastic Fiber Tensometry in the Skin Dermis of Children with Marfan Syndrome., PMID:39273142
N-demethylsinomenine metabolite and its prototype sinomenine activate mast cells via MRGPRX2 and aggravate anaphylaxis., PMID:39144634
Mast cells contribute to T-cell accumulation in the bronchoalveolar space in mice with IL-33-induced airway inflammation., PMID:39132816
Downstream Target Analysis for miR-365 among Oral Squamous Cell Carcinomas Reveals Differential Associations with Chemoresistance., PMID:38929724
Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations., PMID:38806494
Cyto- and Histopographic Assessment of CPA3-Positive Testicular Mast Cells in Obstructive and Non-Obstructive Azoospermia., PMID:38786055
Revealing prognostic insights of programmed cell death (PCD)-associated genes in advanced non-small cell lung cancer., PMID:38728242
Involvement of Mast Cells in the Pathology of COVID-19: Clinical and Laboratory Parallels., PMID:38667325
Disruption of the mast cell carboxypeptidase A3 gene does not attenuate airway inflammation and hyperresponsiveness in two mouse models of asthma., PMID:38578780
Analysis of the potential molecular mechanisms of asthma and gastroesophageal reflux disease., PMID:38517701
Integrated genetic analysis of diabetic complications: Bioinformatics insights into foot ulcers, neuropathy and peripheral artery disease., PMID:38358067
Association between High HbA1c Levels and Mast Cell Phenotype in the Infrapatellar Fat Pad of Patients with Knee Osteoarthritis., PMID:38255949
Exploration of Key Immune-Related Transcriptomes Associated with Doxorubicin-Induced Cardiotoxicity in Patients with Breast Cancer., PMID:37684436
Mast Cell Deficiency in Mice Attenuates Insulin Phenolic Preservative-Induced Inflammation., PMID:37626754
Identification of novel gene signature for lung adenocarcinoma by machine learning to predict immunotherapy and prognosis., PMID:37583701
Bioinformatic Analysis of Key Regulatory Genes in Adult Asthma and Prediction of Potential Drug Candidates., PMID:37241840
Tibetan medicine Liuwei Muxiang pills (LWMX pills) effectively protects mice from chronic non-atrophic gastritis., PMID:37167846
Mast cell deficiency prevents BCR::ABL1 induced splenomegaly and cytokine elevation in a CML mouse model., PMID:37161070
Analysis of human lung mast cells by single cell RNA sequencing., PMID:37063885
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome., PMID:36687269
Increased NMUR1 Expression in Mast Cells in the Synovial Membrane of Obese Osteoarthritis Patients., PMID:36232539
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation., PMID:36225927
RNA-seq characterization of histamine-releasing mast cells as potential therapeutic target of osteoarthritis., PMID:36109004
Dynamically upregulated mast cell CPA3 patterns in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis., PMID:35983043
Mast Cell and Basophil Granule Proteases - In Vivo Targets and Function., PMID:35865537
Gene expression and clinical outcomes after dietary treatment for eosinophilic esophagitis: a prospective study., PMID:35661487
Identification of tumor biomarkers for pathological complete response to neoadjuvant treatment in locally advanced breast cancer., PMID:35597840
Identifying key genes and functionally enriched pathways in Th2-high asthma by weighted gene co-expression network analysis., PMID:35550122
Elastase- and LPS-Exposed Cpa3Cre/+ and ST2-/- Mice Develop Unimpaired Obstructive Pulmonary Disease., PMID:35493481
Four differentially expressed genes can predict prognosis and microenvironment immune infiltration in lung cancer: a study based on data from the GEO., PMID:35184748
RNA-Seq reveals distinct transcriptomic differences in rotator cuff tendon based on tear etiology and patient sex., PMID:35174534
Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity., PMID:35058936
Mast Cells Differentiated in Synovial Fluid and Resident in Osteophytes Exalt the Inflammatory Pathology of Osteoarthritis., PMID:35008966
Tumor Immune Microenvironment Related Gene-Based Model to Predict Prognosis and Response to Compounds in Ovarian Cancer., PMID:34966691
Carboxypeptidase A3 expression in canine mast cell tumors and tissue-resident mast cells., PMID:34894899
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes., PMID:34145303
Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin., PMID:34057753
Effects of Intensive Fattening With Total Mixed Rations on Carcass Characteristics, Meat Quality, and Meat Chemical Composition of Yak and Mechanism Based on Serum and Transcriptomic Profiles., PMID:33553278
Lung Mast Cells Have a High Constitutive Expression of Carboxypeptidase A3 mRNA That Is Independent from Granule-Stored CPA3., PMID:33546258
For research use only. Not for human or drug use.
