Catalog No.
YHD07901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Lys111
Predicted molecular weight
15.71 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14927
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Complex III subunit VII, UQBP, Complex III subunit 7, Ubiquinol-cytochrome c reductase complex 14 kDa protein, Cytochrome b-c1 complex subunit 7, UQCRB, QP-C
UQCRB regulates mitochondrial energy metabolism by promoting COX5 A in atherosclerotic endothelial dysfunction., PMID:40445331
Proteome differences of dental stem cells between permanent and deciduous teeth by data-independent acquisition proteomics., PMID:39886483
Cellular and extracellular proteomic profiling of paradoxical low-flow low-gradient aortic stenosis myocardium., PMID:39355352
UQCRB and LBH are correlated with Gleason score progression in prostate cancer: Spatial transcriptomics and experimental validation., PMID:39310280
Integrative analysis of transcriptome-wide association study and mRNA expression profile identified risk genes for bipolar disorder., PMID:39151574
MiR-125b-1-3p-mediated UQCRB inhibition facilitates mitochondrial metabolism disorders in a rat cellular senescencemodel., PMID:39117291
Integrated bulk and single-cell RNA sequencing identifies an aneuploidy-based gene signature to predict sensitivity of lung adenocarcinoma to traditional chemotherapy drugs and patients' prognosis., PMID:38938612
Single-cell image-based genetic screens systematically identify regulators of Ebola virus subcellular infection dynamics., PMID:38617272
N-Acetyltransferase 10 represses Uqcr11 and Uqcrb independently of ac4C modification to promote heart regeneration., PMID:38459019
Mef2c regulates bone mass through Sost-dependent and -independent mechanisms., PMID:38042445
Novel prognostic features and personalized treatment strategies for mitochondria-related genes in glioma patients., PMID:37091853
High-throughput proteomic characterization of seminal plasma from bulls with contrasting semen quality., PMID:36714547
Identification of diagnostic genes for both Alzheimer's disease and Metabolic syndrome by the machine learning algorithm., PMID:36405716
Screening and validation of nickel ion cytotoxicity biomarkers based on transcriptomic and proteomic technology., PMID:36226165
Identification of key genes and pathways associated with sex differences in rheumatoid arthritis based on bioinformatics analysis., PMID:36173499
Bioinformatic Data Mining for Candidate Drugs Affecting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) in Cancer Patients., PMID:36157219
Effect of downregulated citrate synthase on oxidative phosphorylation signaling pathway in HEI-OC1 cells., PMID:36071491
Identification of Genes Predicting Poor Response of Trastuzumab in Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer., PMID:35935587
Mitochondrial ROS Produced in Human Colon Carcinoma Associated with Cell Survival via Autophagy., PMID:35454800
Homozygous missense mutation in UQCRC2 associated with severe encephalomyopathy, mitochondrial complex III assembly defect and activation of mitochondrial protein quality control., PMID:33865955
Hepatic HuR modulates lipid homeostasis in response to high-fat diet., PMID:32546794
Proteomic analysis of oxidative stress response in human umbilical vein endothelial cells (HUVECs): role of heme oxygenase 1 (HMOX1) in hypoxanthine-induced oxidative stress in HUVECs., PMID:32420127
Investigation of the gene co-expression network and hub genes associated with acute mountain sickness., PMID:32299499
MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer., PMID:32071343
Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells., PMID:31944172
Identification of immunodominant IgE epitopes of the major house dust mite allergen Der f 24., PMID:31545417
Higher lipid turnover and oxidation in cultured human myotubes from athletic versus sedentary young male subjects., PMID:30510272
Hsa-miR-10a-5p downregulation in mutant UQCRB-expressing cells promotes the cholesterol biosynthesis pathway., PMID:30120311
Synthesis, spectroscopic characterization (FT-IR, FT-Raman, and NMR), quantum chemical studies and molecular docking of 3-(1-(phenylamino)ethylidene)-chroman-2,4-dione., PMID:29367024
Mitochondrial UQCRB as a new molecular prognostic biomarker of human colorectal cancer., PMID:29147009
Downregulation of mitochondrial UQCRB inhibits cancer stem cell-like properties in glioblastoma., PMID:29115404
Transcriptome analysis for UVB-induced phototoxicity in mouse retina., PMID:29044990
Mitochondrial markers predict recurrence, metastasis and tamoxifen-resistance in breast cancer patients: Early detection of treatment failure with companion diagnostics., PMID:28978152
Combined Respiratory Chain Deficiency and UQCC2 Mutations in Neonatal Encephalomyopathy: Defective Supercomplex Assembly in Complex III Deficiencies., PMID:28804536
[Analysis of UQCRB gene mutation in a child with mitochondrial complex III deficiency]., PMID:28604960
Identification of UQCRB as an oxymatrine recognizing protein using a T7 phage display screen., PMID:27497639
Cell-permeable mitochondrial ubiquinol-cytochrome c reductase binding protein induces angiogenesis in vitro and in vivo., PMID:26118773
Phenotypic variation of TTC19-deficient mitochondrial complex III deficiency: a case report and literature review., PMID:25899669
A mutation in the mitochondrial protein UQCRB promotes angiogenesis through the generation of mitochondrial reactive oxygen species., PMID:25446085
Development of a novel class of mitochondrial ubiquinol-cytochrome c reductase binding protein (UQCRB) modulators as promising antiangiogenic leads., PMID:25244355
12p microRNA expression in fibroblast cell lines from probands with Pallister-Killian syndrome., PMID:24981202
Mitochondrial UQCRB regulates VEGFR2 signaling in endothelial cells., PMID:23708980
Exploring the role of mitochondrial UQCRB in angiogenesis using small molecules., PMID:23475074
Functional inhibition of UQCRB suppresses angiogenesis in zebrafish., PMID:23454382
Muscle inflammatory signaling in response to 9 days of physical inactivity in young men with low compared with normal birth weight., PMID:22968485
Human embryonic stem cells and embryonal carcinoma cells have overlapping and distinct metabolic signatures., PMID:22768158
Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer., PMID:22545919
Candidate hippocampal biomarkers of susceptibility and resilience to stress in a rat model of depression., PMID:22311638
Identification of tumor suppressors and oncogenes from genomic and epigenetic features in ovarian cancer., PMID:22174824
Identification of a novel small molecule targeting UQCRB of mitochondrial complex III and its anti-angiogenic activity., PMID:21215626
For research use only. Not for human or drug use.
