Catalog No.
YHD05601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp22-Ala311
Predicted molecular weight
34.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14625
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
94 kDa glucose-regulated protein, HSP90B1, gp96 homolog, GRP94, Heat shock protein 90 kDa beta member 1, Endoplasmin, TRA1, Tumor rejection antigen 1, GRP-94
Supplementing sialic acid analogs overcomes radiotherapy resistance in triple-negative breast cancer by exacerbating ER stress., PMID:40505348
Impact of obesity on proteomic profiles of follicular fluid-derived small extracellular vesicles: A comparison between PCOS and non-PCOS women., PMID:40468347
Identification and validation of pyroptosis-related genes in Alzheimer's disease based on multi-transcriptome and machine learning., PMID:40438507
Deciphering the Molecular Crosstalk of Endoplasmic Reticulum Stress and Immune Infiltration in Endometriosis., PMID:40371728
BiP, GRP94, calreticulin and calnexin contribute to development of the notochord in medaka fish., PMID:40368802
Effect of Rehmanniae Radix Extract on Chondrocyte Apoptosis in the Rabbit Model of Knee Osteoarthritis., PMID:40331378
Glucose-regulated protein 94 (Grp94/gp96) in viral pathogenesis: Insights into its role and therapeutic potentials., PMID:40319577
The relationship between serum levels of GRP78, GRP94, calnexin, and calreticulin and prognosis in patients with lung cancer., PMID:40289385
GRP94 is indispensable for definitive endoderm specification of human induced pluripotent stem cells., PMID:40254879
The structural and functional dynamics of BiP and Grp94: opportunities for therapeutic discovery., PMID:40253284
Proteomic insights into the environmental adaptation of the subtropical brain coral host Platygyra carnosa., PMID:40248114
Colon cancer exosome-associated HSP90B1 initiates pre-metastatic niche formation in the liver by polarizing M1 macrophage into M2 phenotype., PMID:40234961
Comprehensive analysis of heat shock proteins in glioma revealed the association with glioma-associated myeloid cells., PMID:40234584
Mechanism of client loading from BiP to Grp94 and its disruption by select inhibitors., PMID:40234402
MiR-148a-3p Loaded Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Alleviates Silica-Induced Pulmonary Fibrosis by Inhibiting β-Catenin Signaling., PMID:40230541
Newborn apical resection preserves the proliferative capacity of cardiomyocytes located throughout the left ventricle., PMID:40229986
ROS-Mediated Unfolded Protein Response Activation Drives Hepatocyte Apoptosis in Mesaconitine-Induced Liver Injury., PMID:40137482
Subacute exposure of male adolescent rats to 2,2',5,5'-tetrachlorobiphenyl-4-ol via a polymeric implant causes gene expression changes in the brain and metabolomic disruption in serum., PMID:40097135
Modeling epilepsy by loss-of-function of the CUG-binding protein Elav-like family member 2 in zebrafish with multi-omics analysis., PMID:40066778
Requirements for nuclear GRP78 transcriptional regulatory activities and interaction with nuclear GRP94., PMID:40024475
Proteomic Analysis of Human Follicular Fluid-Derived Exosomes Reveals That Insufficient Folliculogenesis in Aging Women is Associated With Infertility., PMID:40024376
Transcriptomic and biometric parameters analysis in rainbow trout (Oncorhynchus mykiss) challenged with viral hemorrhagic septicemia virus (VHSV)., PMID:40021981
Distinct Urinary Proteome Changes Across Estimated Glomerular Filtration Rate Stages in a Cohort of Black South Africans., PMID:40004202
In Vitro Inhibition of Endoplasmic Reticulum Stress: A Promising Therapeutic Strategy for Patients with Crohn's Disease., PMID:39996742
Injectable Endoplasmin-Loaded Lipid Nanoparticles-Hydrogel Composite for Cartilage Regeneration., PMID:39992620
GRP94 mediates blood-brain barrier permeation and substantia nigra-specific drug distribution in Parkinson's disease., PMID:39983452
Gp93 safeguards tissue homeostasis by preventing ROS-JNK-mediated apoptosis., PMID:39965405
Increased intracellular stress responses and decreased KLF2 in adult patients with atopic dermatitis., PMID:39938773
No added sugar: CCDC134 stabilizes ER chaperone Gp96 for TLR biogenesis., PMID:39907723
Functional epitope mapping of cell surface glucose-regulated protein 94: A combinatorial approach for therapeutic targeting., PMID:39880265
PD-L1 positive platelets mediate resistance to immune checkpoint inhibitors in patients with colorectal cancer., PMID:39815258
From Genes to Metabolites: HSP90B1's Role in Alzheimer's Disease and Potential for Therapeutic Intervention., PMID:39760808
Comprehensive analysis of heat shock protein 110, 90, 70, 60 families and tumor immune microenvironment characterization in clear cell renal cell carcinoma., PMID:39747468
Secreted extracellular heat shock protein gp96 and inflammatory cytokines are markers of severe malaria outcome., PMID:39732362
Characterization and Inhibition of the Chaperone Function of Plasmodium falciparum Glucose-Regulated Protein 94 kDa (Pf Grp94)., PMID:39670568
CCDC134 controls TLR biogenesis through the ER chaperone Gp96., PMID:39656203
Characterization of the Ubiquitin-Modified Proteome of Recombinant Chinese Hamster Ovary Cells in Response to Endoplasmic Reticulum Stress., PMID:39623727
PU-H71 (NSC 750424): a molecular masterpiece that targets HSP90 in cancer and beyond., PMID:39564119
Regulated N-glycosylation controls chaperone function and receptor trafficking., PMID:39509507
AMPD3 promotes doxorubicin-induced cardiomyopathy through HSP90α-mediated ferroptosis., PMID:39474068
Selective Inhibition of hsp90 Paralogs: Uncovering the Role of Helix 1 in Grp94-Selective Ligand Binding., PMID:39473058
Nanocarriers Targeting Circular RNA ADARB1 Boost Radiosensitivity of Nasopharyngeal Carcinoma through Synergically Promoting Ferroptosis., PMID:39467079
The Atlantic Cod MHC I compartment has the properties needed for cross-presentation in the absence of MHC II., PMID:39455705
A transcriptomics-based analysis of mechanisms involved in the neurobehavioral effects of 6PPD-quinone on early life stages of zebrafish., PMID:39454255
Effects of treadmill exercise on endoplasmic reticulum protein folding and endoplasmic reticulum-associated protein degradation pathways in APP/PS1 mice., PMID:39397952
CD91 and Its Ligand gp96 Confer Cross-Priming Capabilities to Multiple APCs during Immune Responses to Nascent, Emerging Tumors., PMID:39269437
Preliminary study of BF/C2 on immune mechanism of grass carp against GCRV infection., PMID:39048939
Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives., PMID:39043265
N-Glycosylation-Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules., PMID:39042517
Unveiling the Hub Genes Involved in Cadmium-Induced Hepatotoxicity., PMID:39012411
For research use only. Not for human or drug use.
