Catalog No.
YHD05501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Tyr99
Predicted molecular weight
37.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P14621
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Acylphosphate phosphohydrolase 2, Acylphosphatase, muscle type isozyme, ACYP2, Acylphosphatase-2, ACYP
ACYP2 functions as an innovative nano-therapeutic target to impede the progression of hepatocellular carcinoma by inhibiting the activity of TERT and the KCNN4/ERK pathway., PMID:39267048
Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes., PMID:39211229
Transcription factor 7 like 2 gene polymorphism and advanced glycation end products as risk factors for diabetic nephropathy., PMID:38985530
Study of the effect of ACYP2 single nucleotide polymorphisms rs843711 and rs843706 in Egyptian patients with hepatocellular carcinoma., PMID:38615271
Amyloid Aggregation Is Potently Slowed Down by Osmolytes Due to Compaction of Partially Folded State., PMID:37734431
Systematic Critical Review of Genetic Factors Associated with Cisplatin-induced Ototoxicity: Canadian Pharmacogenomics Network for Drug Safety 2022 Update., PMID:37726872
Systematic Review and Meta-Analysis of the Influence of Genetic Variation on Ototoxicity in Platinum-Based Chemotherapy., PMID:36802061
ACPY2 gene polymorphisms on cancer risk: a systematic review and meta-analysis., PMID:35797106
Plasma Proteins as Occupational Hazard Risk Monitors for Populations Working in Harsh Environments: A Mendelian Randomization Study., PMID:35602164
Genetically Determined Telomere Length Is Associated with Pancreatic Neuroendocrine Neoplasms Onset., PMID:35472852
Association of obesity in T2DM with differential polymorphism of ghrelin, growth hormone secretagogue receptor-1 and telomeres maintenance genes., PMID:35446515
Telomere Length and Male Fertility., PMID:33921254
Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma., PMID:33115534
The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM., PMID:32937184
Usefulness of current candidate genetic markers to identify childhood cancer patients at risk for platinum-induced ototoxicity: Results of the European PanCareLIFE cohort study., PMID:32905960
ACYP2 contributes to malignant progression of glioma through promoting Ca2+ efflux and subsequently activating c-Myc and STAT3 signals., PMID:32517717
Association between ACYP2 polymorphisms and the risk of renal cell cancer., PMID:31487124
Association between the ACYP2 Polymorphisms and IgAN Risk in the Chinese Han Population., PMID:31291640
Assessment of the association between ACYP2 and laryngeal squamous cell carcinoma risk in Chinese males., PMID:31140742
Associations between polymorphisms of the ACYP2 gene and Liver cancer risk: A case-control study and meta-analysis., PMID:31124313
The influence of ACYP2 polymorphisms on gastrointestinal cancer susceptibility in the Chinese Han population., PMID:31070019
Predictors of cisplatin-induced ototoxicity and survival in chemoradiation treated head and neck cancer patients., PMID:30732962
Oxadiazon affects the expression and activity of aldehyde dehydrogenase and acylphosphatase in human striatal precursor cells: A possible role in neurotoxicity., PMID:30391265
Genetic determinants of telomere length and risk of pancreatic cancer: A PANDoRA study., PMID:30325019
Genetic and Modifiable Risk Factors Contributing to Cisplatin-induced Toxicities., PMID:30305294
Analyzing the clinical actionability of germline pharmacogenomic findings in oncology., PMID:29742281
Further Investigation of the Role of ACYP2 and WFS1 Pharmacogenomic Variants in the Development of Cisplatin-Induced Ototoxicity in Testicular Cancer Patients., PMID:29358504
Single Nucleotide Polymorphisms in the Acylphosphatase 2 Gene and The SNP-SNP Interactions on the Risk of Breast Cancer in Chinese Han Women., PMID:29033240
The effects of gene polymorphisms on glioma prognosis., PMID:28985021
TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity., PMID:28445188
Response to the letter to the editor by D. Yuan: "Risk of high altitude pulmonary edema and telomere length"., PMID:28444911
Leukocyte telomere length-related genetic variants in ACYP2 contribute to the risk of esophageal carcinoma in Chinese Han population., PMID:28424424
Association analysis of telomere length related gene ACYP2 with the gastric cancer risk in the northwest Chinese Han population., PMID:28415712
Association between genetic polymorphism of telomere-associated gene ACYP2 and the risk of HAPE among the Chinese Han population: A Case-control study., PMID:28353602
Genetic polymorphisms in the telomere length-related gene ACYP2 are associated with the risk of colorectal cancer in a Chinese Han population., PMID:28039478
Association of polymorphisms in the telomere-related gene ACYP2 with lung cancer risk in the Chinese Han population., PMID:27974682
Genetic variants in the acylphosphatase 2 gene and the risk of breast cancer in a Han Chinese population., PMID:27894080
Association of ACYP2 and TSPYL6 Genetic Polymorphisms with Risk of Ischemic Stroke in Han Chinese Population., PMID:27686078
Telomere length-related gene ACYP2 polymorphism is associated with the risk of HAPE in Chinese Han population., PMID:27552709
Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers., PMID:27207662
Replication of a genetic variant in ACYP2 associated with cisplatin-induced hearing loss in patients with osteosarcoma., PMID:26928270
Association between previously identified loci affecting telomere length and coronary heart disease (CHD) in Han Chinese population., PMID:24904205
Screening of potential pseudo att sites of Streptomyces phage ΦC31 integrase in the human genome., PMID:23416928
Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients., PMID:22020760
Differentially expressed genes and morphological changes during lengthened immobilization in rat soleus muscle., PMID:17316384
Characterization of a novel Drosophila melanogaster acylphosphatase., PMID:12560098
For research use only. Not for human or drug use.
