Catalog No.
RHN70401
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, WB: 1:1000-1:2000
Target
Carma 1, CARMA1, CARD-containing MAGUK protein 1, CARD11, Caspase recruitment domain-containing protein 11
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9BXL7
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2Q55
Clinical outcomes of newly diagnosed PCNSL treated with rituximab-methotrexate-cytarabine with or without ibrutinib: a retrospective study., PMID:40475774
Monoallelic expression can govern penetrance of inborn errors of immunity., PMID:39743591
Mutational Landscape of Bone Marrow CD19 and CD138 Cells in Waldenström Macroglobulinemia (WM) and IgM Monoclonal Gammopathy of Undetermined Significance (IgM MGUS)., PMID:39711167
The efficacy and safety of ZR2 versus R-CHOP-like for elderly patients with newly diagnosed diffuse large B cell lymphoma: a single-center prospective study in China., PMID:39472318
B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection., PMID:39082968
Management of Atopy with Dupilumab and Omalizumab in CADINS Disease., PMID:38231347
Prurigo-like atopic dermatitis in a child with CARD11-associated severe combined immunodeficiency successfully treated with dupilumab., PMID:37888582
Hyper IgE Syndromes., PMID:37702167
Efficacy and safety of zanubrutinib plus R-CHOP in treatment of non-GCB DLBCL with extranodal involvement., PMID:37671152
Clinical relevance of molecular aspects in extranodal marginal zone lymphoma: a critical appraisal., PMID:37389189
A case of cold agglutinin syndrome associated with chronic lymphocytic leukaemia harbouring mutations in CARD11 and KMT2D., PMID:37133636
Molecular Biomarker Exploration of Rituximab plus CHOP Therapy in Real-World Diffuse Large B-Cell Lymphoma Patients., PMID:36649512
m6A-Regulator Expression Signatures Identify a Subset of Follicular Lymphoma Harboring an Exhausted Tumor Microenvironment., PMID:35734168
Hyper-IgE and Carcinoma in CADINS Disease., PMID:35651609
Phosphorylation of serine-893 in CARD11 suppresses the formation and activity of the CARD11-BCL10-MALT1 complex in T and B cells., PMID:35230873
Decreased expression of T-cell-associated immune markers predicts poor prognosis in patients with follicular lymphoma., PMID:34837284
Identification of GPC3 mutation and upregulation in a multidrug resistant osteosarcoma and its spheroids as therapeutic target., PMID:34611509
Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management., PMID:34447369
Hyper-IgE syndrome, 2021 update., PMID:34419355
Aberrant Immunoglobulin Kappa Locus Rearrangement in a Patient with CARD11-Related B Cell Lymphocytosis., PMID:34355353
Pathway-Specific Defects in T, B, and NK Cells and Age-Dependent Development of High IgE in Mice Heterozygous for a CADINS-Associated Dominant Negative CARD11 Allele., PMID:34341167
Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency., PMID:33872653
Efficacy of dupilumab for controlling severe atopic dermatitis with dominant-negative CARD11 variant., PMID:33864281
Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma., PMID:33479306
Screening for Genetic Mutations for the Early Diagnosis of Common Variable Immunodeficiency in Children With Refractory Immune Thrombocytopenia: A Retrospective Data Analysis From a Tertiary Children's Center., PMID:33425813
Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-κB Activation Pathway., PMID:33329596
Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas., PMID:33232972
Activity of ibrutinib plus R-CHOP in diffuse large B-cell lymphoma: Response, pharmacodynamic, and biomarker analyses of a phase Ib study., PMID:33188997
B cell receptor signaling related to resistance to Helicobacter pylori eradication therapy in gastric diffuse large B cell lymphoma., PMID:33034903
The Child with Elevated IgE and Infection Susceptibility., PMID:32830295
Survey of Blood Groups DEA 1, DEA 4, DEA 5, Dal, and Kai 1/Kai 2 in Different Canine Breeds From a Diagnostic Laboratory in Germany., PMID:32185185
Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody., PMID:32059783
MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells., PMID:31644910
Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders., PMID:31572362
M7-FLIPI is not prognostic in follicular lymphoma patients with first-line rituximab chemo-free therapy., PMID:31423576
Mutations of the B-Cell Receptor Pathway Confer Chemoresistance in Primary Cutaneous Diffuse Large B-Cell Lymphoma Leg Type., PMID:31150604
Ubiquitination and phosphorylation of the CARD11-BCL10-MALT1 signalosome in T cells., PMID:30514565
An Update on Syndromes with a Hyper-IgE Phenotype., PMID:30466772
Simulation of the Dynamics of Primary Immunodeficiencies in B Cells., PMID:30116248
Hyper-IgE in the allergy clinic--when is it primary immunodeficiency?, PMID:30043993
A multiprotein supercomplex controlling oncogenic signalling in lymphoma., PMID:29925955
MYD88, CARD11, and CD79B Oncogenic Mutations are Rare Events in the Indian Cohort of De Novo Nodal Diffuse Large B-Cell Lymphoma., PMID:29734251
Intrinsic Plasma Cell Differentiation Defects in B Cell Expansion with NF-κB and T Cell Anergy Patient B Cells., PMID:28824638
Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma., PMID:28682481
B-cell Function Gene Mutations in Diffuse Large B-cell Lymphoma: A Retrospective Cohort Study., PMID:28153771
Simultaneous Inhibition of PI3Kδ and PI3Kα Induces ABC-DLBCL Regression by Blocking BCR-Dependent and -Independent Activation of NF-κB and AKT., PMID:28073005
MYD88, CD79B, and CARD11 gene mutations in CD5-positive diffuse large B-cell lymphoma., PMID:27915469
B-cell receptor-driven MALT1 activity regulates MYC signaling in mantle cell lymphoma., PMID:27864294
Rewired NFκB signaling as a potentially actionable feature of activated B-cell-like diffuse large B-cell lymphoma., PMID:27526684
Mechanisms of NF-κB deregulation in lymphoid malignancies., PMID:27262792
For research use only. Not for human or drug use.
