Catalog No.
RHN61902
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Polyadenylate-binding protein 2, PABP-2, PABII, PABPN1, Polyadenylate-binding nuclear protein 1, Poly(A)-binding protein 2, PAB2, Poly(A)-binding protein II, PABP2, Nuclear poly(A)-binding protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q86U42
Applications
FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2P23
Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change., PMID:36732296
PABPN1L assemble into "ring-like" aggregates in the cytoplasm of MII oocytes and is associated with female infertility†., PMID:34726234
Value of insoluble PABPN1 accumulation in the diagnosis of oculopharyngeal muscular dystrophy., PMID:31769567
An Antibody to Detect Alanine-Expanded PABPN1: A New Tool to Study Oculopharyngeal Muscular Dystrophy., PMID:27858752
Atrophy, fibrosis, and increased PAX7-positive cells in pharyngeal muscles of oculopharyngeal muscular dystrophy patients., PMID:23399899
Structural basis for a PABPN1 aggregation-preventing antibody fragment in OPMD., PMID:20226184
Castration induces autoantibody and T cell responses that correlate with inferior outcomes in an androgen-dependent murine tumor model., PMID:19554630
Prevention of oculopharyngeal muscular dystrophy by muscular expression of Llama single-chain intrabodies in vivo., PMID:19258344
Prevention of oculopharyngeal muscular dystrophy-associated aggregation of nuclear polyA-binding protein with a single-domain intracellular antibody., PMID:16319127
Llama-derived phage display antibodies in the dissection of the human disease oculopharyngeal muscular dystrophy., PMID:12969556
Nuclear poly(A)-binding protein PABPN1 is associated with RNA polymerase II during transcription and accompanies the released transcript to the nuclear pore., PMID:12749861
For research use only. Not for human or drug use.
