Catalog No.
RHN59805
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Applications
FCM, WB
Recommended Dilution
| Application |
Dilution |
| FCM |
1:20-1:100, WB: 1:1000-1:2000 |
Target
Calcium/calmodulin dependent protein kinase II alpha, Calcium/calmodulin dependent protein kinase II beta, Calcium/calmodulin dependent protein kinase II delta, Calcium/calmodulin dependent protein kinase II gamma, CaM kinase II alpha, CaM kinase II, CaM kinase II beta, CaM kinase II delta, CaM kinase II gamma, CAMK2, Camk2a, CAMK2B, CAMK2D, CAMK2G, CAMKA, pan CaMKII
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UQM7, Q13554, Q13555, Q13557
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2P05
Note
For research use only.
Specific distribution of Ca2+/calmodulin-dependent protein kinase II alpha and beta isoforms in some structures of the rat forebrain., PMID:7820660
Alpha calcium/calmodulin-dependent protein kinase II immunoreactivity in corticospinal neurons: combination of axonal transport method and immunofluorescence., PMID:7486009
An alternative, nonkinase product of the brain-specifically expressed Ca2+/calmodulin-dependent kinase II alpha isoform gene in skeletal muscle., PMID:8524307
alpha-calcium-calmodulin-dependent kinase II is associated with paired helical filaments of Alzheimer's disease., PMID:8800091
Calcium/calmodulin-dependent protein kinase II expression in motor neurons: effect of axotomy., PMID:9369152
The absence of a major Ca2+ signaling pathway in GABAergic neurons of the hippocampus., PMID:9501248
Regional differences between the immunohistochemical distribution of Ca2+/calmodulin-dependent protein kinase II alpha and beta isoforms in the brainstem of the rat., PMID:9593859
Localization of CaMKIIalpha in rat primary sensory neurons: increase in inflammation., PMID:12176168
Volume-regulated anion conductance in cultured rat cerebral astrocytes requires calmodulin activity., PMID:15095369
The expression of calcium/calmodulin-dependent protein kinase II-alpha in the hippocampus of patients with Alzheimer's disease and its links with AD-related pathology., PMID:15621017
Phosphorylation of tau at serine 416 by Ca2+/calmodulin-dependent protein kinase II in neuronal soma in brain., PMID:16000144
A role for the calmodulin kinase II-related anchoring protein (αkap) in maintaining the stability of nicotinic acetylcholine receptors., PMID:22496563
Immune response profiling identifies autoantibodies specific to Moyamoya patients., PMID:23518061
Trichostatin A protects against cisplatin-induced ototoxicity by regulating expression of genes related to apoptosis and synaptic function., PMID:23558232
Membrane actions of 1α,25(OH)2D3 are mediated by Ca(2+)/calmodulin-dependent protein kinase II in bone and cartilage cells., PMID:25263660
An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice., PMID:26476406
A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma., PMID:28892521
Cell Type-Specific Survey of Epigenetic Modifications by Tandem Chromatin Immunoprecipitation Sequencing., PMID:29348483
Ketamine reduces remifentanil-induced postoperative hyperalgesia mediated by CaMKII-NMDAR in the primary somatosensory cerebral cortex region in mice., PMID:31541650
Selective targeting of mRNA and the following protein synthesis of CaMKIIα at the long-term potentiation-induced site., PMID:31874853
Gliosis Precedes Amyloid-β Deposition and Pathological Tau Accumulation in the Neuronal Cell Cycle Re-Entry Mouse Model of Alzheimer's Disease., PMID:32904753
Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain., PMID:35614064
Profiling the autoantibody repertoire reveals autoantibodies associated with mild cognitive impairment and dementia., PMID:38107644
Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia., PMID:38751620
For research use only. Not for human or drug use.
