Catalog No.
YHD00101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln79-Arg318
Predicted molecular weight
54.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13686
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ACP5, Tartrate-resistant acid ATPase, TR-AP, TrATPase, Tartrate-resistant acid phosphatase type 5, Type 5 acid phosphatase
Effect of vitamin B1 supplementation on bone turnover markers in adults: an exploratory single-arm pilot study., PMID:40371216
Norwogonin Attenuates Inflammatory Osteolysis and Collagen-Induced Arthritis via Modulating Redox Signalling and Calcium Oscillations., PMID:40099974
The regulatory role of ACP5 in the diesel exhaust particle-induced AHR inflammatory signaling pathway in a human bronchial epithelial cell line., PMID:40087344
Arcyriaflavin A Alleviates Osteoporosis by Suppressing RANKL-Induced Osteoclastogenesis., PMID:40076762
The DHH-DHHA1 domain phosphodiesterase of Mycoplasma bovis employs multiple strategies to modulate macrophage cellular processes., PMID:40023422
TRAPping the effects of tobacco smoking: the regulation and function of Acp5 expression in lung macrophages., PMID:39993028
Isonardosinone attenuates osteoclastogenesis and OVX-induced bone loss via the MAPK/NF-κB pathway., PMID:39956462
The Sirt1/FOXO signal pathway involves in regulating osteomyelitis progression via modulating mitochondrial dysfunctions and osteogenic differentiation., PMID:39939446
Molecular Profiling of Odontoclasts during Physiological Tooth Replacement., PMID:39876039
Clinical, laboratory, and molecular characteristics of patients with spondyloenchondrodysplasia: a case series study., PMID:39853520
[Effect of osteon-like concentric microgroove structures of different sizes on the osteoclastic differentiation of macrophages]., PMID:39848804
Identification of therapeutic target genes for age-related hearing loss through systematic genome-wide mendelian randomization of druggable genes., PMID:39778696
Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast., PMID:39773351
Stigmasterol mitigates estrogen-deficiency-induced osteoporosis through inhibition of phosphorylated p65 and MAPK signaling pathways., PMID:39741634
Development and characterization of an in vitro fluorescently tagged 3D bone-cartilage interface model., PMID:39600948
A NOTCH2 pathogenic variant and HES1 regulate osteoclastogenesis in induced pluripotent stem cells., PMID:39571704
A rare case of late-onset spondyloenchondrodysplasia with immune dysregulation presenting as adult-onset monogenic lupus., PMID:39560632
4-Hydroxyphenylacetic Acid, a microbial-derived metabolite of Polyphenols, inhibits osteoclastogenesis by inhibiting ROS production., PMID:39520963
Substrate-Mediated Regulation of Src Expression Drives Osteoclastogenesis Divergence., PMID:39336808
Trends of bone mineral density and bone quality in a paediatric kidney transplant recipient: A case report., PMID:39315463
Levels of B-ALP and TRAP-5b in a patient with short root anomaly: a case report., PMID:39275837
Candidate Biomarkers for Response to Treatment in Psoriatic Disease., PMID:39218451
Irilin D suppresses RANKL-induced osteoclastogenesis and prevents inflammation-induced bone loss by disrupting the NF-κB and MAPK signaling pathways., PMID:39209096
Cross-talk between oxidative stress and lipid metabolism regulators reveals molecular clusters and immunological characterization in polycystic ovarian syndrome., PMID:39143634
Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes bone length, regulates cortical and trabecular bone mass, and maintains growth plate architecture and width in a sex- and site-specific manner in mice., PMID:39111379
EPSTI1 promotes osteoclast differentiation and bone resorption by PKR/NF-κB signaling., PMID:39083969
Investigating the Underlying Molecular Mechanisms of Yunke on Bone Metastases from Prostate Cancer., PMID:39071978
Overexpression of the receptor for resolvin E1 (ERV1) prevents early alveolar bone loss in leptin receptor deficiency-induced diabetes., PMID:39031577
The diagnostic and prognostic value of tartrate-resistant acid phosphatase isoform 5b for giant cell tumor of bone., PMID:38995462
Ginsenoside Rb3 alleviates the formation of osteoclasts induced by periodontal ligament fibroblasts in the periodontitis microenvironment through the STAT3 pathway., PMID:38934258
14-3-3ζ suppresses RANKL signaling by destabilizing TRAF6., PMID:38908751
Development of a nanoparticle-based tendon-targeting drug delivery system to pharmacologically modulate tendon healing., PMID:38896625
Inhibition of tartrate-resistant acid phosphatase 5 can prevent cardiac fibrosis after myocardial infarction., PMID:38879488
Inhibition of caspase-8 cascade restrains the osteoclastogenic fate of bone marrow cells., PMID:38833170
Ctdnep1 phosphatase is required for negative regulation of RANKL-induced osteoclast differentiation in RAW264.7 cells., PMID:38749090
Detection of genetic mutations underlying early-onset systemic lupus erythematosus., PMID:38739464
Therapeutic potential of a prominent dihydroxyflavanone pinocembrin for osteolytic bone disease: In vitro and in vivo evidence., PMID:38685969
The Expression and Secretion Profile of TRAP5 Isoforms in Gaucher Disease., PMID:38667330
Cycloastragenol prevents bone loss via inhibiting osteoclast activity in glucocorticoid-induced osteonecrosis of the femoral head: An in vivo study., PMID:38549807
Exposure to per- and polyfluoroalkyl substances and high-throughput proteomics in Hispanic youth., PMID:38537583
Association of serum sodium levels with fractures and mortality in patients undergoing maintenance hemodialysis., PMID:38512372
RNA-based bone histomorphometry: method and its application to explaining postpubertal bone gain in a G610C mouse model of osteogenesis imperfecta., PMID:38477760
Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes., PMID:38460933
SPI1 exacerbates iron accumulation and promotes osteoclast formation through inhibiting the expression of Hepcidin., PMID:38450475
The novel cytotoxic polybisphosphonate osteodex decreases bone resorption by enhancing cell death of mature osteoclasts without affecting osteoclastogenesis of RANKL-stimulated mouse bone marrow macrophages., PMID:38427117
STING inhibition alleviates bone resorption in apical periodontitis., PMID:38411951
Zoledronic acid enhances tumor growth and metastatic spread in a mouse model of jaw osteosarcoma., PMID:38376129
Studies on the in vitro mechanism and in vivo therapeutic effect of the antimicrobial peptide ACP5 against Trichophyton mentagrophytes., PMID:38354953
Case report: Refractory Evans syndrome in two patients with spondyloenchondrodysplasia with immune dysregulation treated successfully with JAK1/JAK2 inhibition., PMID:38347954
Piperlongumine, a Piper longum-derived amide alkaloid, protects mice from ovariectomy-induced osteoporosis by inhibiting osteoclastogenesis via suppression of p38 and JNK signaling., PMID:38311970
For research use only. Not for human or drug use.
