Catalog No.
RHK71201
Species reactivity
Human, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Applications
IHC, WB
Recommended Dilution
| Application |
Dilution |
| IHC |
1:50-1:100, WB: 1:500-1:1000 |
Target
Aminopeptidase PILS, ARTS1, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, PILS-AP, Endoplasmic reticulum aminopeptidase 1, ARTS-1, A-LAP, Puromycin-insensitive leucyl-specific aminopeptidase, APPILS, ERAP1, KIAA0525, Adipocyte-derived leucine aminopeptidase
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NZ08
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2M95
Note
For research use only.
Endoplasmic reticulum aminopeptidase-1 mediates leukemia inhibitory factor-induced cell surface human leukocyte antigen-G expression in JEG-3 choriocarcinoma cells., PMID:16439450
Localization of angiotensin II, the AT1 receptor, angiotensin-converting enzyme, aminopeptidase A, adipocyte-derived leucine aminopeptidase, and vascular endothelial growth factor in the human ovary throughout the menstrual cycle., PMID:16769060
The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation., PMID:17277129
Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer., PMID:19243813
Natural killer cells efficiently reject lymphoma silenced for the endoplasmic reticulum aminopeptidase associated with antigen processing., PMID:21252114
Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study., PMID:21326860
Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort., PMID:21574996
Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis., PMID:22355039
[Genetic risk factors for vasculitis]., PMID:24217527
Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27., PMID:24504800
TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages., PMID:24688025
A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene., PMID:25369137
Genetics of vasculitis., PMID:25405820
Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease: genetics., PMID:26002026
Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis., PMID:26130142
KIR3DL1 interaction with HLA-B27 is altered by ankylosing spondylitis associated ERAP1 and enhanced by MHC class I cross-linking., PMID:26321090
A Pharmacogenetic Study of Psoriasis Risk Variants in a Greek Population and Prediction of Responses to Anti-TNF-α and Anti-IL-12/23 Agents., PMID:27043841
ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface., PMID:27107845
Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid arthritis., PMID:27342690
Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis., PMID:27564082
Behçet's disease: An immunogenetic perspective., PMID:30341905
HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis., PMID:30578879
Paradoxical psoriasis induced by TNF-α blockade shows immunological features typical of the early phase of psoriasis development., PMID:31577850
Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoprotein., PMID:34688668
ERAP/HLA-C and KIR Genetic Profile in Couples with Recurrent Implantation Failure., PMID:36293373
Serum biomarkers and their relationship to axial spondyloarthritis associated with inflammatory bowel diseases., PMID:38168574
ERAP-1 and ERAP-2 Variants in Liver Injury After COVID-19 mRNA Vaccination: A US Multicenter Study., PMID:38314748
ERAP1 and ERAP2 gene variants as potential clinical biomarkers of anti-interleukin-17A response in psoriasis vulgaris., PMID:38616723
Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population., PMID:39906739
For research use only. Not for human or drug use.
