Catalog No.
RHK71201
Species reactivity
Human, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
Aminopeptidase PILS, ARTS1, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator, PILS-AP, Endoplasmic reticulum aminopeptidase 1, ARTS-1, A-LAP, Puromycin-insensitive leucyl-specific aminopeptidase, APPILS, ERAP1, KIAA0525, Adipocyte-derived leucine aminopeptidase
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NZ08
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2M95
Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population., PMID:39906739
ERAP1 and ERAP2 gene variants as potential clinical biomarkers of anti-interleukin-17A response in psoriasis vulgaris., PMID:38616723
ERAP-1 and ERAP-2 Variants in Liver Injury After COVID-19 mRNA Vaccination: A US Multicenter Study., PMID:38314748
Serum biomarkers and their relationship to axial spondyloarthritis associated with inflammatory bowel diseases., PMID:38168574
ERAP/HLA-C and KIR Genetic Profile in Couples with Recurrent Implantation Failure., PMID:36293373
Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoprotein., PMID:34688668
Paradoxical psoriasis induced by TNF-α blockade shows immunological features typical of the early phase of psoriasis development., PMID:31577850
HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis., PMID:30578879
Behçet's disease: An immunogenetic perspective., PMID:30341905
Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis., PMID:27564082
Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid arthritis., PMID:27342690
ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface., PMID:27107845
A Pharmacogenetic Study of Psoriasis Risk Variants in a Greek Population and Prediction of Responses to Anti-TNF-α and Anti-IL-12/23 Agents., PMID:27043841
KIR3DL1 interaction with HLA-B27 is altered by ankylosing spondylitis associated ERAP1 and enhanced by MHC class I cross-linking., PMID:26321090
Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis., PMID:26130142
Endoplasmic reticulum-associated amino-peptidase 1 and rheumatic disease: genetics., PMID:26002026
Genetics of vasculitis., PMID:25405820
A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene., PMID:25369137
TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages., PMID:24688025
Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27., PMID:24504800
[Genetic risk factors for vasculitis]., PMID:24217527
Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis., PMID:22355039
Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort., PMID:21574996
Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study., PMID:21326860
Natural killer cells efficiently reject lymphoma silenced for the endoplasmic reticulum aminopeptidase associated with antigen processing., PMID:21252114
Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer., PMID:19243813
The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation., PMID:17277129
Localization of angiotensin II, the AT1 receptor, angiotensin-converting enzyme, aminopeptidase A, adipocyte-derived leucine aminopeptidase, and vascular endothelial growth factor in the human ovary throughout the menstrual cycle., PMID:16769060
Endoplasmic reticulum aminopeptidase-1 mediates leukemia inhibitory factor-induced cell surface human leukocyte antigen-G expression in JEG-3 choriocarcinoma cells., PMID:16439450
For research use only. Not for human or drug use.
