Catalog No.
YHC99101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val509-Leu858
Predicted molecular weight
41.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13639
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EF-2, EF2, EEF2, Elongation factor 2
Orchestrating Neural Development Through mRNA Translation Regulation., PMID:40509688
Unveiling the Potential Binding Targets of Celastrol in Colorectal Cancer: A Proteomic Profiling Approach Integrating Cellular Thermal Shift Assay and Pulse Proteolysis., PMID:40480957
The Critical Role of the C-terminal Lobe of Calmodulin in Activating Eukaryotic Elongation Factor 2 Kinase., PMID:40462953
Differential expression of lysine-acetylated proteins in the anti-inflammatory effects of luteolin-gadolinium on macrophages., PMID:40435707
SERCA activation prevents Ca2+ and ATP upregulation during 3-day soleus muscle unloading in rats., PMID:40433945
A Coordinated Translational Control Mediated by eEF2 Phosphorylation Safeguards Erythroid Differentiation., PMID:40429942
Targeting eEF2K induces oxidative stress and sensitizes cancer cells to ferroptosis induction., PMID:40409701
(R)-ketamine induces mGlu5 receptor-dependent antidepressant-like effects in the chronic unpredictable mild stress model of depression in mice., PMID:40342162
Protective Effects of Rat Bone Marrow Mesenchymal Stem Cells-Derived Fusogenic Plasma Membrane Vesicles Containing VSVG Protein Mediated Mitochondrial Transfer on Myocardial Injury In Vitro., PMID:40330432
Regulation of translation elongation and integrated stress response in heat-shocked neurons., PMID:40286269
Mendelian randomization study on the causal relationships among fasting blood glucose, plasma proteins, and squamous cell lung cancer., PMID:40263141
The Effect of Valine on the Synthesis of α-Casein in MAC-T Cells and the Expression and Phosphorylation of Genes Related to the mTOR Signaling Pathway., PMID:40243924
Screening colorectal cancer associated autoantigens through multi-omics analysis and diagnostic performance evaluation of corresponding autoantibodies., PMID:40240912
Multi-channel smFRET study reveals a compact conformation of EF-G on the ribosome., PMID:40210088
Diphthamide formation in Arabidopsis requires DPH1-interacting DPH2 for light and oxidative stress resistance., PMID:40200557
Structural basis for hygromycin B inhibition of yeast pseudouridine-deficient ribosomes., PMID:40173234
Endurance exercise with reduced muscle glycogen content influences substrate utilization and attenuates acute mTORC1- and autophagic signaling in human type I and type II muscle fibers., PMID:40128889
In-Silico Screening-Based Discovery of New Natural eEF2K Inhibitors with Neuritogenic Activity., PMID:40104800
Molecular insights into human soleus muscle atrophy development: long-term dry immersion effects on the transcriptomic profile and posttranslational signaling., PMID:40072920
AMPK Activation Downregulates TXNIP, Rab5, and Rab7 Within Minutes, Thereby Inhibiting the Endocytosis-Mediated Entry of Human Pathogenic Viruses., PMID:40072063
Deep Hypothermic Low Flow Results in Multiple Aspects of Neurological Deficits in Mice by eEF2 Hyperphosphorylation., PMID:40014267
Dual Translational Control in Cardiomyocytes by Heterogeneous mTORC1 and Hypertrophic ERK Activation., PMID:39990478
Linking KATP channel activation to p-AKT/mTORC1/eEF2/BDNF axis unravels Nicorandil's promise in countering acetaminophen-induced hepatic encephalopathy in mice., PMID:39983823
Eukaryotic Elongation Factor 2 Kinase EFK-1/eEF2K promotes starvation resistance by preventing oxidative damage in C. elegans., PMID:39966347
High-throughput screening of thermal tolerant candidate genes in the ivory shell (Babylonia areolata) based on the yeast strain INVSc1., PMID:39889586
Diphthamide synthesis is linked to the eEF2-client chaperone machinery., PMID:39825589
Comparing the malignant properties of parental and a knock-in version of HCT116 cell line expressing the CDK2-mutant of eukaryotic elongation factor 2 (eEF2)., PMID:39804540
Improved Malignancy of Colon Cancer Cells at Gene Expression Level With Constitutive Activation of the Eukaryotic Elongation Factor 2 Under Nutrition-Deficient Conditions., PMID:39803701
Capturing eukaryotic ribosome dynamics in situ at high resolution., PMID:39789210
CT-Scan-Assessed Body Composition and Its Association with Tumor Protein Expression in Endometrial Cancer: The Role of Muscle and Adiposity Quantities., PMID:39766121
Indole and Coumarin Derivatives Targeting EEF2K in Aβ Folding Reporter Cells., PMID:39754378
Antibiotics/coccidiostat exposure induces gut-brain axis remodeling for Akt/mTOR activation and BDNF-mediated neuroprotection in APEC-infected turkeys., PMID:39721265
Elongation factor 2 in cancer: a promising therapeutic target in protein translation., PMID:39707196
Hsa_Circ_0105596/FTO inhibits progression of Parkinson's disease by sponging miR-187-3p and regulating eEF2., PMID:39654770
Hsp90 and cochaperones have two genetically distinct roles in regulating eEF2 function., PMID:39652595
Macrophage Dvl2 deficiency promotes NOD1-Driven pyroptosis and exacerbates inflammatory liver injury., PMID:39644526
Identification and validation of ATP6V1G1-regulated phosphorylated proteins in hepatocellular carcinoma., PMID:39621600
Depression-like effects induced by chronic unpredictable mild stress in mice are rapidly reversed by a partial negative allosteric modulator of mGlu5 receptor, M-5MPEP., PMID:39615019
eEF2K as an important kinase associated with cancer survival and prognosis., PMID:39592671
Anabolic Sensitivity in Healthy, Lean, Older Men Is Associated With Higher Expression of Amino Acid Sensors and mTORC1 Activators Compared to Young., PMID:39558870
Identification of significant hub genes and pathways associated with metastatic breast cancer and tolerogenic dendritic cell via bioinformatics analysis., PMID:39549529
SARM1 deficiency induced depressive-like behavior via AMPKα/p-eEF2 axis to synapse dysfunction., PMID:39489288
Exploring the Regulatory Interaction of Differentially Expressed Proteins in Cleft Palate Induced by Retinoic Acid., PMID:39473103
Loss of Diphthamide Increases DNA Replication Stress in Mammalian Cells by Modulating the Translation of RRM1., PMID:39463834
EIF4A3-Induced Circular RNA CircDdb1 Promotes Muscle Atrophy through Encoding a Novel Protein CircDdb1-867aa., PMID:39412095
Another decade of antimalarial drug discovery: New targets, tools and molecules., PMID:39370241
EEF2-Related Neurodevelopmental Disorder Is Clinically Recognizable., PMID:39359947
Extracellular Vesicle Inhibitors Enhance Cholix-Induced Cell Death via Regulation of the JNK-Dependent Pathway., PMID:39330838
Exogenous interactome analysis of bovine viral diarrhea virus-host using network based-approach and identification of hub genes and important pathways involved in virus pathogenesis., PMID:39318471
For research use only. Not for human or drug use.
