Catalog No.
RHK54102
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Target
Non-homologous end-joining factor 1, XRCC4-like factor, NHEJ1, XLF, Protein cernunnos
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H9Q4
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2M41
X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology., PMID:34056803
Structural basis of long-range to short-range synaptic transition in NHEJ., PMID:33854234
Extreme Phenotypes With Identical Mutations: Two Patients With Same Non-sense NHEJ1 Homozygous Mutation., PMID:30666249
PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line., PMID:27601633
XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination., PMID:27281794
Dynamic changes in subcellular localization of cattle XLF during cell cycle, and focus formation of cattle XLF at DNA damage sites immediately after irradiation., PMID:25947322
Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis., PMID:22312109
A primary immunodeficiency characterized by defective immunoglobulin class switch recombination and impaired DNA repair., PMID:17485519
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly., PMID:16439204
For research use only. Not for human or drug use.
