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Anti-POT1 Antibody (R2M20)

Catalog #:   RHK46301 Specific References (20) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: WB
Accession: Q9NUX5
Overview

Catalog No.

RHK46301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

WB: 1:500-1:1000

Target

Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein, POT1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NUX5

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2M20

Data Image
  • Western blot
    Western blot analysis of POT1 in K562, C6, 3T3 lysates using POT1 antibody.
References

Chronic Lymphocytic Leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing., PMID:38175592

Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia., PMID:34518531

The intrinsically disordered N-terminal region of mouse DNA polymerase alpha mediates its interaction with POT1a/b at telomeres., PMID:33711210

Chronic lymphocytic leukemia patients with IGH translocations are characterized by a distinct genetic landscape with prognostic implications., PMID:32720348

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases., PMID:32514122

Pathophysiology of chronic lymphocytic leukemia and human B1 cell development., PMID:31797231

Mechanism of Action of G-Quadruplex-Forming Oligonucleotide Homologous to the Telomere Overhang in Melanoma., PMID:29203363

Profile of POT1 as telomerase shelterin component discriminatesbetween cervical cancer and normal cervical cells., PMID:28425274

Telomere Dysfunction Induced Foci (TIF) Analysis., PMID:27500188

Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle., PMID:27386862

Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy., PMID:27226433

Evidence for multiple forms and modifications of human POT1., PMID:24054699

Altered expression of TPP1 in fibroblast-like synovial cells might be involved in the pathogenesis of rheumatoid arthritis., PMID:21833529

First Report of Pepper mottle virus in Bell Pepper in Taiwan., PMID:30731963

ssDNA fragments induce cell senescence by telomere uncapping., PMID:18778766

Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells., PMID:17050546

Alternative splicing of Pot1 (Protection of telomere)-like genes in Arabidopsis thaliana., PMID:15824455

Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins., PMID:15383534

POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex., PMID:15231715

Structure and metabolic control of the Yarrowia lipolytica peroxisomal 3-oxoacyl-CoA-thiolase gene., PMID:7916689

Datasheet

Document Download

Anti-POT1 Antibody (R2M20).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

Contact Information

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For research use only. Not for human or drug use.

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Anti-POT1 Antibody (R2M20) [RHK46301]
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