Catalog No.
RHK44602
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Applications
FCM, IF, IHC, IP, WB
Recommended Dilution
| Application |
Dilution |
| FCM |
1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000 |
Target
Mitotic arrest deficient 2-like protein 2, Mitotic spindle assembly checkpoint protein MAD2B, MAD2L2, MAD2-like protein 2, hREV7, REV7, REV7 homolog, MAD2B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UI95
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2M13
Note
For research use only.
Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint., PMID:11707408
Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores., PMID:15964272
High expression of REV7 is an independent prognostic indicator in patients with diffuse large B-cell lymphoma treated with rituximab., PMID:26449786
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity., PMID:29656893
SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice., PMID:30154076
REV7 is required for processing AID initiated DNA lesions in activated B cells., PMID:32499490
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2., PMID:32830536
Analysis of translesion polymerases in colorectal cancer cells following cetuximab treatment: A network perspective., PMID:39102671
CST Is Epistatic With Shieldin to Limit DNA Double-Strand Break End Resection and Promote Repair During Igh Class Switch Recombination., PMID:40178294
For research use only. Not for human or drug use.
