Catalog No.
YHC98001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln31-Met617
Predicted molecular weight
70.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13521
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
SCG2, Chromogranin-C, Secretogranin-2, Secretogranin II, SgII, CHGC, SN
Design and synthesis of 3,4-seco-lupane triterpene-tryptamine derivatives and revealing their anti-bladder cancer mechanisms by combining TCGA and transcriptomic approaches., PMID:40473811
Placental transcriptome reveals the placental brain axis genes and pathways of gestational diabetes mellitus (GDM) affecting offspring neurodevelopment., PMID:40298873
Integrated bioinformatics analysis identifies neutrophils and villous cytotrophoblasts infiltration characterized by BLC6 upregulation as associated with the co-occurrence of gestational diabetes mellitus and pre-eclampsia., PMID:40122115
The Role of miR-155 in Modulating Gene Expression in CD4+ T Cells: Insights into Alternative Immune Pathways in Autoimmune Encephalomyelitis., PMID:39518908
SCG2 Mediates HNSCC Progression With CCL2/TGFβ1high M2 Macrophage Infiltration., PMID:39404611
SCG2 mediates blood-brain barrier dysfunction and schizophrenia-like behaviors after traumatic brain injury., PMID:39225388
SCG2 and CPE may be novel markers for the identification of pancreatic neuroendocrine tumors and solid pseudopapillary neoplasms., PMID:39145076
Comprehensive analysis of anoikis-related genes in diagnosis osteoarthritis: based on machine learning and single-cell RNA sequencing data., PMID:38423139
Urinary exosomal mRNA as a biomarker for the diagnosis of bladder cancer., PMID:38385960
Prognostic value of plasma secretoneurin concentration in patients with heart failure with reduced ejection fraction in one-year follow-up., PMID:38261566
Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients., PMID:38191511
Circulating secretoneurin level reflects angiographic coronary collateralization in stable angina patients with chronic total occlusion., PMID:38184555
Estrogen-dependent expression and function of secretogranin 2a in female-specific peptidergic neurons., PMID:38111823
Unraveling immunotherapeutic targets for endometriosis: a transcriptomic and single-cell analysis., PMID:38035102
Role of human dural fibroblasts in the angiogenic responses of human endothelial cells: An in vitro dural model and the application of lab-on-a-chip for EDAS., PMID:38023706
[High expression of secretogranin II increases oxaliplatin resistance of colorectal cancer cells]., PMID:37933640
Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways., PMID:37848672
The choroidal nervous system: a link between mineralocorticoid receptor and pachychoroid., PMID:37682293
Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease., PMID:37468915
Mechanisms of ag85a/b DNA vaccine conferred immunotherapy and recovery from Mycobacterium tuberculosis-induced injury., PMID:37249284
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease., PMID:37160957
Function of secretoneurin in regulating the expression of reproduction-related genes in ovoviviparous black rockfish (Sebastes schlegelii)., PMID:37028701
Bone marrow-derived mesenchymal stem cells accelerate angiogenesis in pregnant experimentally induced deep venous thrombosis rat model via up-regulation of pro-angiogenic secretogranin II., PMID:36933488
Identification of MMP9 as a Novel Biomarker to Mitochondrial Metabolism Disorder and Oxidative Stress in Calcific Aortic Valve Stenosis., PMID:36199424
Identification of immune subtypes to guide immunotherapy and targeted therapy in clear cell renal cell carcinoma., PMID:36057262
Screening and identification of immune-related genes for immunotherapy and prognostic assessment in colorectal cancer patients., PMID:35941638
SCG2: A Prognostic Marker That Pinpoints Chemotherapy and Immunotherapy in Colorectal Cancer., PMID:35844556
Development of a prognostic signature based on immune-related genes and the correlation with immune microenvironment in breast cancer., PMID:35793235
Construction and Validation of Angiogenesis-Related Prognostic Risk Signature to Facilitate Survival Prediction and Biomarker Excavation of Breast Cancer Patients., PMID:35498539
AGTR1, PLTP, and SCG2 associated with immune genes and immune cell infiltration in calcific aortic valve stenosis: analysis from integrated bioinformatics and machine learning., PMID:35341274
Effect of surgical damage to spinal nerve on dorsal-root ganglion gene expressions: Comprehensive analysis of differentially expressed genes., PMID:35184964
SCG2 is a Prognostic Biomarker Associated With Immune Infiltration and Macrophage Polarization in Colorectal Cancer., PMID:35047505
Nanoplasmonic immunosensor for the detection of SCG2, a candidate serum biomarker for the early diagnosis of neurodevelopmental disorder., PMID:34815513
Extensive NEUROG3 occupancy in the human pancreatic endocrine gene regulatory network., PMID:34352411
Revealing NOTCH-dependencies in synaptic targets associated with Alzheimer's disease., PMID:34314836
An increase in VGF expression through a rapid, transcription-independent, autofeedback mechanism improves cognitive function., PMID:34238925
Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia-inducible factor-1α in colorectal cancer., PMID:34160138
Identification of key genes in calcific aortic valve disease via weighted gene co-expression network analysis., PMID:34020624
The role of noble bumblebee (Bombus terrestris) queen glycosaminoglycan in aged rat and gene expression profile based on DNA microarray., PMID:33489860
Identification of four novel prognosis biomarkers and potential therapeutic drugs for human colorectal cancer by bioinformatics analysis., PMID:33361643
Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network., PMID:33299180
Secretoneurin is a secretogranin-2 derived hormonal peptide in vertebrate neuroendocrine systems., PMID:32828813
Establishment and validation of an immune-associated signature in lung adenocarcinoma., PMID:32799112
Transcriptomic approach predicts a major role for transforming growth factor beta type 1 pathway in L-Dopa-induced dyskinesia in parkinsonian rats., PMID:32741046
Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach., PMID:32552841
A comprehensive systematic review of CSF proteins and peptides that define Alzheimer's disease., PMID:32518535
Secretogranin III upregulation is involved in parkinsonian toxin-mediated astroglia activation., PMID:32404559
Interleukin-6 increases adrenal androgen release by regulating the expression of steroidogenic proteins in NCI-H295R cells., PMID:32346900
Fasting before or after wound injury accelerates wound healing through the activation of pro-angiogenic SMOC1 and SCG2., PMID:32206122
Tumor Transcriptome Reveals High Expression of IL-8 in Non-Small Cell Lung Cancer Patients with Low Pectoralis Muscle Area and Reduced Survival., PMID:31455042
For research use only. Not for human or drug use.
