Catalog No.
RHJ87301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Applications
IF, IHC, WB
Recommended Dilution
| Application |
Dilution |
| IF |
1:50-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000 |
Target
Mitochondrial fission 1 protein, FIS1 homolog, Tetratricopeptide repeat protein 11, FIS1, TTC11, hFis1, TPR repeat protein 11
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y3D6
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2L10
Note
For research use only.
The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1., PMID:12861026
The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction., PMID:18845145
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease., PMID:19605646
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage., PMID:21459773
Homocysteine-mediated modulation of mitochondrial dynamics in retinal ganglion cells., PMID:21642619
Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission., PMID:21701560
Dynamic changes of mitochondrial fission proteins after transient cerebral ischemia in mice., PMID:22498177
Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment., PMID:22529290
IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse., PMID:22769563
The mitochondrial Dnm1-like fission component is required for lgA2-induced mitophagy but dispensable for starvation-induced mitophagy in Ustilago maydis., PMID:22843561
The mitochondrial elongation factors MIEF1 and MIEF2 exert partially distinct functions in mitochondrial dynamics., PMID:23880462
Effect of Qiangji Jianli decoction on mitochondrial respiratory chain activity and expression of mitochondrial fusion and fission proteins in myasthenia gravis rats., PMID:29872094
Expression of mitochondrial dynamics markers during melanoma progression: Comparative study of head and neck cutaneous and mucosal melanomas., PMID:30916813
Apolipoprotein E negatively regulates murine allergic airway inflammation via suppressing the activation of NLRP3 inflammasome and oxidative stress., PMID:32062073
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293
A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly., PMID:33633281
Photobiomodulation therapy with light-emitting diode in stimulating adipose tissue mitochondria., PMID:37851070
Melatonin ameliorates Pb-induced mitochondrial homeostasis and ovarian damage through regulating the p38 signaling pathway., PMID:39983510
[Mechanism of the pretreatment with electroacupuncture of "biaoben acupoint combination" for regulating cardiomyocyte mitochondrial fission in the rats of myocardial ischemia-reperfusion injury]., PMID:40097217
For research use only. Not for human or drug use.
