Catalog No.
YHC95601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg1268-Leu1516
Predicted molecular weight
31.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12883
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYH7, Myosin heavy chain slow isoform, MyHC-beta, MyHC-slow, MYHCB, Myosin heavy chain 7, Myosin heavy chain, cardiac muscle beta isoform, Myosin-7
Perinatal death in pig models of hypertrophic cardiomyopathy carrying sarcomere pathogenic variants., PMID:40496056
Knockout of the Staphylococcus aureus virulence gene sdrC promotes Myh7 expression to inhibit the progression of osteomyelitis., PMID:40471432
Application of RNA-seq for single nucleotide variation identification in a cohort of patients with hypertrophic cardiomyopathy., PMID:40442228
Modulation of striated-muscle contractility by a high-affinity myosin-targeting peptide., PMID:40432208
Unravelling the Genotype of the Apical Variant of Hypertrophic Cardiomyopathy in a Swedish Cohort., PMID:40428316
Altered Lactylation Myocardial Tissue May Contribute to a More Severe Energy-Deprived State of the Tissue and Left Ventricular Outflow Tract Obstruction in HOCM., PMID:40281739
Relationship between the expression of striated preferentially expressed gene (SPEG) and the development of atrial fibrillation., PMID:40223983
The gut microbiota metabolite trimethylamine N-oxide promotes cardiac hypertrophy by activating the autophagic degradation of SERCA2a., PMID:40210720
Methylophiopogonanone A alleviates diabetic cardiomyopathy via inhibiting JNK1 signaling., PMID:40139620
The Future of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 Gene Therapy in Cardiomyopathies: A Review of Its Therapeutic Potential and Emerging Applications., PMID:40130092
snRNA-Seq and Spatial Transcriptome Reveal Cell-Cell Crosstalk Mediated Metabolic Regulation in Porcine Skeletal Muscle., PMID:40079370
Hypertrophic Cardiomyopathy: Genes and Mechanisms., PMID:40018920
Sodium Butyrate Alleviates Heat Stress-Induced Oxidative Stress and Skeletal Muscle Homeostasis Disruption by Promoting Autophagy in Mice., PMID:40005024
Clinical and Genetic Heterogeneity of HCM: The Possible Role of a Deletion Involving MYH6 and MYH7., PMID:40004541
Disrupted maxillofacial, cardiovascular, and nervous development in washc5 knockout Zebrafish: Insights into 3C syndrome., PMID:39988189
Increased Matrix Stiffness Promotes Slow Muscle Fibre Regeneration After Skeletal Muscle Injury., PMID:39969079
Celecoxib Enhances Oxidative Muscle Fibre Formation and Improves Muscle Functions Through Prokr1 Activation in Mice., PMID:39887895
Astragali Radix-Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance., PMID:39855831
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice., PMID:39806512
Prevention of Muscle Atrophy by Low-Molecular-Weight Fraction from Hirsutella sinensis Mycelium., PMID:39727967
Endpoint Selection in Randomized Clinical Trials for Hypertrophic Cardiomyopathy., PMID:39708028
Three Novel Pathogenic Variants in Unrelated Vietnamese Patients with Cardiomyopathy., PMID:39682617
Sarcomere gene variants did not improve cardiac function in pediatric patients with dilated cardiomyopathy from Japanese cohorts., PMID:39681577
[Correlation between genotype and clinical phenotype in hypertrophic cardiomyopathy families with MYH7-R453C mutation]., PMID:39681440
Comprehensive bioinformatics and machine learning analyses for breast cancer staging using TCGA dataset., PMID:39656775
Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor in early-stage Hypertrophic Cardiomyopathy., PMID:39647438
Obstructive hypertrophic cardiomyopathy: from genetic insights to a multimodal therapeutic approach with mavacamten, aficamten, and beyond., PMID:39645546
Unique Genetic Profiles in Hypertrophic Cardiomyopathy Patients From São Miguel Island (Azores, Portugal)., PMID:39605252
YAK577 Attenuates Cardiac Remodeling and Fibrosis in Isoproterenol-Infused Heart Failure Mice by Downregulating MMP12., PMID:39601396
Subcellular mass spectrometric detection unveils hyperglycemic memory in the diabetic heart., PMID:39539089
Comparative Proteomic and Phosphoproteomic Analyses Reveal Molecular Signatures of Myocardial Infarction and Transverse Aortic Constriction in Aged Mouse Models., PMID:39502510
Clinical Features and Outcomes of Pediatric MYH7-Related Dilated Cardiomyopathy., PMID:39494569
Long noncoding RNA VENTHEART is required for ventricular cardiomyocyte specification and function., PMID:39490643
Proteomic analysis of wild boar meat: Effect of storage method and time on muscle protein stability., PMID:39486280
Dominant myosin storage myopathy mutations disrupt striated muscles in Drosophila and the myosin tail-tail interactome of human cardiac thick filaments., PMID:39485824
Genetics of Exertional Heat Illness: Revealing New Associations and Expanding Heterogeneity., PMID:39457051
MYH7-related myopathies: clinical, myopathological and genotypic spectrum in a multicentre French cohort., PMID:39448255
Searching for genetic determinants for left ventricular non-compaction., PMID:39429584
Mechanism of the cardioprotective effect of empagliflozin on diabetic nephropathy mice based on the basis of proteomics., PMID:39427190
Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TNNI3 c.235C > T variant., PMID:39426416
Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis., PMID:39425025
Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling., PMID:39413182
Prevalence, Penetrance, and Phenotypic Manifestation of Cardiomyopathy-Associated Genetic Variants in the General Population: Insights from a Mayo Clinic Biobank Study., PMID:39387793
USP20 deletion promotes eccentric cardiac remodeling in response to pressure overload and increases mortality., PMID:39365672
Promotion of maturation in CDM3-induced embryonic stem cell-derived cardiomyocytes by palmitic acid., PMID:39331088
Silver Nanoparticles Exposure Impairs Cardiac Development by Suppressing the Focal Adhesion Pathway in Zebrafish., PMID:39282573
Differential analysis of ubiquitin-proteomics in skeletal muscle of Duroc pigs and Tibetan fragrant pigs., PMID:39280835
Case report: Additional variants induced sudden cardiac death among pediatric ACM with DSG2 homozygous mutant genotype: a report of three cases., PMID:39253717
For research use only. Not for human or drug use.
