Catalog No.
YHC95201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp155-Asp367
Predicted molecular weight
25.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12830
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD324, Uvomorulin, Epithelial cadherin, E-cadherin, CDHE, CAM 120/80, UVO, CDH1, Cadherin-1
E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway., PMID:40421484
Lipopolysaccharide induces retention of E-cadherin in the endoplasmic reticulum and promotes hybrid epithelial-to-mesenchymal transition of human embryonic stem cells-derived expandable lung epithelial cells., PMID:40413286
TMBIM1 promotes epithelial mesenchymal transition by accelerating autophagic degradation of E-cadherin in glioblastoma., PMID:40394049
Hereditary diffuse gastric and lobular breast cancer syndrome associated with germline CDH1 variants: focus on lobular breast cancer., PMID:40366456
The Clinical Relevance of Epithelial-to-Mesenchymal Transition Hallmarks: A Cut-Off-Based Approach in Healthy and Cancerous Cell Lines., PMID:40332096
PCSK9 promotes progression of anaplastic thyroid cancer through E-cadherin endocytosis., PMID:40328788
Colonoscopy findings in CDH1 carriers from a multicenter international study., PMID:40323501
Transcription factor BACH1 promotes epithelial-mesenchymal transition by repressing iron metabolism-related genes., PMID:40315568
Association between proband characteristics and CDH1 cascade genetic testing uptake in at-risk relatives., PMID:40305395
The Association of Aquaporins with MAPK Signaling Pathway Unveils Potential Prognostic Biomarkers for Pancreatic Cancer: A Transcriptomics Approach., PMID:40305202
The DNA Methylation is Involved in Liver Cancer Metastasis via Regulation of E- cadherin Gene., PMID:40302090
KRIBB11 Exerts Anticancer Effects on A172 Glioblastoma Cells via the Cdh1/SKP2/p27 and HSF1/p53/p21 Pathways., PMID:40280718
Prognostic Value of <em>SOX9</em>, <em>E-Cadherin</em>, and <em>KLF4</em> Expressions in Clear Cell Renal Carcinoma., PMID:40235245
Advancing the Evaluation and Management of CDH1-Associated Gastric Cancer., PMID:40203872
Micro-proteomics reveals distinct protein profiles and SPARC/FGF2/CDH1 regulation of human Sertoli cells between Sertoli cell-only syndrome and normal men., PMID:40192810
COPD susceptibility gene HHIP regulates repair genes in airway epithelial cells and repair within the epithelial-mesenchymal trophic unit., PMID:40192657
CDH1 genetic variants and its aberrant expression are the risk factors for colorectal cancer metastasis., PMID:40169954
Sustained chromosomal passenger complex activity preserves the pluripotency of human embryonic carcinoma cells., PMID:40136047
CCL2 expression predicts clinical outcomes and regulates E-cadherin and angiogenesis in pituitary tumours., PMID:40063010
Association of XRCC gene family and CDH1 gene polymorphisms with gastric cancer risk in a Chinese population., PMID:40059436
Afadin loss induces breast cancer metastasis through destabilisation of E-cadherin to F-actin linkage., PMID:40026293
Loss of E-cadherin Activates EGFR-MEK/ERK Signaling, Promoting Cervical Cancer Progression., PMID:39993806
Potentiated Effects of Photobiomodulation and Celecoxib on the Epithelial-Mesenchymal Transition Signaling of E-Cadherin, N-Cadherin, α-SMA in Breast Cancer Cells, MCF7, and MDA-MB-231., PMID:39992209
KDM1A Acts as an Oncogene and Facilitates the Epithelial Mesenchymal Transition Process in Gastric Cancer., PMID:39907114
The Oncopromoting Gene RBM6 Inhibits Prostate Tumour Cell Migration During Epithelial-to-Mesenchymal Transition., PMID:39900560
Alpha-linolenic acid-mediated epigenetic reprogramming of cervical cancer cell lines., PMID:39895102
Integrating E-cadherin expression levels with TNM staging for enhanced prognostic prediction in colorectal cancer patients., PMID:39871234
Epithelial mesenchymal transition and cancer stem cell markers in oral epithelial dysplasia and oral squamous cell carcinoma., PMID:39849873
Aberrant E-cadherin Expression in Lobular Carcinoma In Situ: A Comprehensive Immunohistochemical Evaluation of N-terminal, Extracellular, and C-terminal E-cadherin Domains., PMID:39807823
Tyrosine phosphatase SHP2 accelerated ovarian cancer via modulating integrin/ E-Cadherin/ ZEB1 induced EMT., PMID:39789103
The Patterns of P53, E-Cadherin, β-Catenin, CXCR4 and Podoplanin Expression in Oral Squamous Cell Carcinoma Suggests a Hybrid Invasion Model: an Immunohistochemical Study on Tissue Microarrays., PMID:39776043
Adolescents and young adults with germline CDH1 variants and the risk of overtreatment., PMID:39760880
A 3D Computational Study on the Formation and Progression of Tumor Cells in Diffuse Gastric Cancer., PMID:39755811
Invasive lobular carcinoma of the breast: we diagnose it, but do we know what it is?, PMID:39748709
A TAF11 variant contributes to non-syndromic cleft lip only through modulating neural crest cell migration., PMID:39727181
DNA Methylation Pattern and mRNA Expression Level of E-Cadherin and P16 Genes in Thrombotic Disorders., PMID:39711001
Validation of the NCCN/Yale criteria for the identification of CDH1 pathogenic variant carriers., PMID:39674581
Downregulation of lncRNA-MALAT1, Altered Immunohistochemical Expression of Cyclin D1 Protein and E-Cadherin Protein in Correlation to Meningioma Grades., PMID:39611935
The Recurrent E-Cadherin (CDH1) Mutation c.760G>A Causes Orofacial Clefts but Does Not Predispose to Hereditary Cancer., PMID:39596675
The Inhibitory Effect of Hedera helix and Coptidis Rhizome Mixture in the Pathogenesis of Laryngopharyngeal Reflux: Cleavage of E-Cadherin in Acid-Exposed Primary Human Pharyngeal Epithelial Cells., PMID:39596310
FMNL3 Promotes Migration and Invasion of Breast Cancer Cells via Inhibiting Rad23B-Induced Ubiquitination of Twist1., PMID:39582466
Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation., PMID:39567505
Six2 regulates the malignant progression and 5-FU resistance of hepatocellular carcinoma through the PI3K/AKT/mTOR pathway and DNMT1/E-cadherin methylation mechanism., PMID:39556430
Linking CDH1 SNPs to gastric cancer risk: a comprehensive analysis of rs16260, rs13689, and rs9929218., PMID:39550749
Comprehensive characterization of invasive mammary carcinoma with lobular features: integrating morphology and E-cadherin immunohistochemistry patterns., PMID:39549221
Lessons learned from 150 total gastrectomies for prevention of cancer., PMID:39547590
MAD2L2 Dimerization Is Not Essential for Mitotic Regulation., PMID:39519037
Exploration and identification of diabetes targets in nursing: CDH1 and DVL1., PMID:39495995
Homologous Targeting Effect of Cancer Cell-Derived Liposomes (Memposomes) Mediated by Cell Adhesion Molecules: Role of E-cadherin., PMID:39456144
E-cadherin/CD34 double immunostaining in placental diagnosis., PMID:39451172
For research use only. Not for human or drug use.
