Catalog No.
RHJ43103
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IP: 1:20-1:50, WB: 1:1000-1:2000
Target
Glutamate decarboxylase 1, GAD1, GAD-67, Glutamate decarboxylase 67 kDa isoform, GAD67, GAD, 67 kDa glutamic acid decarboxylase
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q99259
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2J78
Novel Therapies for ANCA-associated Vasculitis: Apilimod Ameliorated Endothelial Cells Injury through TLR4/NF-κB Pathway and NLRP3 Inflammasome., PMID:38910483
Tumor-derived GABA promotes lung cancer progression by influencing TAMs polarization and neovascularization., PMID:37977069
Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse., PMID:35551574
Rats deficient in the GAD65 isoform exhibit epilepsy and premature lethality., PMID:33236473
Perineuronal nets and subtypes of GABAergic cells differentiate auditory and multisensory nuclei in the intercollicular area of the midbrain., PMID:32304096
Long-term outcomes in temporal lobe epilepsy with glutamate decarboxylase antibodies., PMID:32221776
Frequency of type I and II diabetes in newly diagnosed diabetic patients: Measuring C-Peptide level., PMID:31235102
Glutamate decarboxylase 67 contributes to compensatory insulin secretion in aged pancreatic islets., PMID:31084527
Global Ubiquitome Profiling Revealed the Roles of Ubiquitinated Proteins in Metabolic Pathways of Tea Leaves in Responding to Drought Stress., PMID:30862833
Abundant glutamic acid decarboxylase (GAD)-reactive B cells in gad-antibody-associated neurological disorders., PMID:30635933
Mesial temporal lobe epilepsy with hippocampal sclerosis is infrequently associated with neuronal autoantibodies., PMID:30146688
Abnormalities in cortical interneuron subtypes in ephrin-B mutant mice., PMID:29904965
Peripheral GABAA receptor-mediated signaling facilitates persistent inflammatory hypersensitivity., PMID:29634983
Latent autoimmune diabetes and limbic encephalitis with antibodies against glutamic acid decarboxylase., PMID:29154389
Identifying the appropriate time for deep brain stimulation to achieve spatial memory improvement on the Morris water maze., PMID:28264667
Neuropeptide Y Y5 receptor localization in mouse central nervous system., PMID:27984021
Cerebellar ataxia and autoantibodies restricted to glutamic acid decarboxylase 67 (GAD67)., PMID:27806870
A Missense Mutation of the Gene Encoding Synaptic Vesicle Glycoprotein 2A (SV2A) Confers Seizure Susceptibility by Disrupting Amygdalar Synaptic GABA Release., PMID:27471467
c-Jun N-terminal Kinase mediates prostaglandin-induced sympathoexcitation in rats with chronic heart failure by reducing GAD1 and GABRA1 expression., PMID:27439062
Different parvalbumin and GABA expression in human epileptogenic focal cortical dysplasia., PMID:27173597
Long latency between GAD-antibody detection and development of limbic encephalitis--a case report., PMID:26420440
Genes in the GABA Pathway Increase in the Lateral Thalamus of Sprague-Dawley Rats During the Proestrus/Estrus Phase., PMID:26388520
Substance P excites GABAergic neurons in the mouse central amygdala through neurokinin 1 receptor activation., PMID:26334021
Neuronal connectivity between habenular glutamate-kisspeptin1 co-expressing neurons and the raphe 5-HT system., PMID:26250886
α-Synuclein expression in the mouse cerebellum is restricted to VGluT1 excitatory terminals and is enriched in unipolar brush cells., PMID:25917213
Antibodies to inhibitory synaptic proteins in neurological syndromes associated with glutamic acid decarboxylase autoimmunity., PMID:25774787
High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells., PMID:25681349
The prevalence of latent autoimmune diabetes in adults and its correlates in patients with type 2 diabetes in Kerman, Iran [2011]., PMID:25470643
Cerebellum neurotransmission during postnatal development: [Pt(O,O'-acac)(γ-acac)(DMS)] vs cisplatin and neurotoxicity., PMID:25450526
Baseline heterogeneity in glucose metabolism marks the risk for type 1 diabetes and complicates secondary prevention., PMID:25381193
Characterization of continuous B-cell epitopes in the N-terminus of glutamate decarboxylase67 using monoclonal antibodies., PMID:25358241
Septal projections to nucleus incertus in the rat: bidirectional pathways for modulation of hippocampal function., PMID:25269409
Impact of islet autoimmunity on the progressive β-cell functional decline in type 2 diabetes., PMID:25239783
Characteristic expressions of GABA receptors and GABA producing/transporting molecules in rat kidney., PMID:25188493
IgG accumulates in inhibitory hippocampal neurons of experimental antiphospholipid syndrome., PMID:25150791
Regional and age-related differences in GAD67 expression of parvalbumin- and calbindin-expressing neurons in the rhesus macaque auditory midbrain and brainstem., PMID:25091320
Immunofluorescently labeling glutamic acid decarboxylase 65 coupled with confocal imaging for identifying GABAergic somata in the rat dentate gyrus-A comparison with labeling glutamic acid decarboxylase 67., PMID:25058170
Hypoxic preconditioning differentially affects GABAergic and glutamatergic neuronal cells in the injured cerebellum of the neonatal rat., PMID:25032984
Inhibitory and excitatory amino acid neurotransmitters are utilized by the projection from the dorsal deep mesencephalic nucleus to the sublaterodorsal nucleus REM sleep induction zone., PMID:24751569
LADA and CARDS: a prospective study of clinical outcome in established adult-onset autoimmune diabetes., PMID:24722498
Aromatase and estrogen receptor beta expression in the rat olfactory bulb: Neuroestrogen action in the first relay station of the olfactory pathway?, PMID:24718039
Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice., PMID:24589481
Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum., PMID:24448211
A protocol for concurrent high-quality immunohistochemical and biochemical analyses in adult mouse central nervous system., PMID:24325300
Characterization of galectin-1-positive cells in the mouse hippocampus., PMID:24323124
Status epilepticus alters neurogenesis and decreases the number of GABAergic neurons in the septal dentate gyrus of 9-day-old rats at the early phase of epileptogenesis., PMID:23623775
Limbic encephalitis in Taiwanese children and adolescence: a single center study., PMID:23597520
Distribution and neurochemical features of neuronal nitric oxide synthase-expressing interneurons in the rat dentate gyrus., PMID:23419891
Three types of neurochemical projection from the bed nucleus of the stria terminalis to the ventral tegmental area in adult mice., PMID:23238719
Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants., PMID:23042297
For research use only. Not for human or drug use.
