Catalog No.
YHC94101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile29-Val262
Predicted molecular weight
28.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12544
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
H factor, CTLA3, Cytotoxic T-lymphocyte proteinase 1, CTL tryptase, Fragmentin-1, HFSP, HF, Granzyme A, Granzyme-1, GZMA, Hanukkah factor
Exploring the pathways linking fasting insulin to coronary artery disease: a proteome-wide Mendelian randomization study., PMID:40442727
Bioinformatics and system biology approach to discover the common pathogenetic processes between COVID-19 and chronic hepatitis B., PMID:40408617
A novel plant-derived recombinant COBRA infectious bronchitis virus spike protein can elicit a strong immune response in chickens., PMID:40358746
Peripheral blood GATA2 expression impacts RNF213 mutation penetrance and clinical severity in moyamoya disease., PMID:40268337
Association of the characteristics of brain magnetic resonance imaging with genes related to disease onset in schizophrenia patients., PMID:40158807
DNA methylation-predicted plasma protein levels and breast cancer risk., PMID:40140843
GZMA silencing inhibits JAK2/STAT1 pathway and improves allergic rhinitis., PMID:40116417
Blood and tissue HIV-1 reservoirs display plasticity and lack of compartmentalization in virally suppressed people., PMID:40038305
Notch dependent chromatin remodeling enables Gata3 binding and drives lineage specific CD8+ T cell function., PMID:40012375
Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer., PMID:39969975
Significance of CD8+T cells related gene ITGB2 in prognosis and tumor microenvironment of small cell lung cancer., PMID:39960961
The T-box transcription factor plays an important role in regulating the immunoregulatory function of double-negative T cells., PMID:39955950
Exploration and Identification of Potential Biomarkers and Immune Cell Infiltration Analysis in Synovial Tissue of Rheumatoid Arthritis., PMID:39953769
High temperature induces oxidative damage, immune modulation, and atrophy in the gills and skeletal muscle of the teleost fish black cusk-eel (Genypterus maculatus)., PMID:39892682
Identification of potential biomarkers associated with cuproptosis and immune microenvironment analysis in acute myocardial infarction: A diagnostic accuracy study., PMID:39889200
Elucidating the molecular association and potential mechanisms between psoriasis and atrial fibrillation through biomarker and immune infiltration analysis., PMID:39776247
Integrated Mendelian Randomization and Single-Cell Transcriptomics Analysis Identifies Critical Blood Biomarkers and Potential Mechanisms in Epilepsy., PMID:39753851
Comparative analysis of WC1.1+ and WC1.2+ γδ T cell subset responses from cattle naturally infected with Mycobacterium bovis to repeat stimulation with mycobacterial antigens., PMID:39666627
SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire., PMID:39656519
IL7R, GZMA and CD8A serve as potential molecular biomarkers for sepsis based on bioinformatics analysis., PMID:39654893
Granzyme A as biomarker for diagnosis in tuberculous pleural effusion., PMID:39641275
Effect of acute exercise on gene expression in peripheral blood mononuclear cells of puberty children., PMID:39543149
Early-life thymectomy leads to an increase of granzyme-producing γδ T cells in children with congenital heart disease., PMID:39537635
Granzyme mRNA-miRNA interaction and its implication to functional impact., PMID:39528794
Key role for inflammation-related signaling in the pathogenesis of myopia based on evidence from proteomics analysis., PMID:39379387
Engineering of a Multi-Modular DNA Nanodevice for Spatioselective Imaging and Evaluation of NK Cell-Mediated Cancer Immunotherapy., PMID:39375853
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease., PMID:39367435
Determination of key hub genes in Leishmaniasis as potential factors in diagnosis and treatment based on a bioinformatics study., PMID:39342024
An exploratory clinical study of β-glucan combined with camrelizumab and SOX chemotherapy as first-line treatment for advanced gastric adenocarcinoma., PMID:39253086
Proteolysis of tau by granzyme A in tauopathies generates fragments that are aggregation prone., PMID:39248243
The role of GZMA as a target of cysteine and biomarker in Alzheimer's disease, pelvic organ prolapse, and tumor progression., PMID:39228516
Single-cell RNA and T-cell receptor sequencing unveil mycosis fungoides heterogeneity and a possible gene signature., PMID:39169943
Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection., PMID:39137883
Single-cell RNA sequencing comparison of CD4+, CD8+ and T-cell receptor γδ+ cutaneous T-cell lymphomas reveals subset-specific molecular phenotypes., PMID:39133553
Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis., PMID:39088396
Multiplex plasma protein assays as a diagnostic tool for lung cancer., PMID:39080998
Association of CD8+TILs co-expressing granzyme A and interferon-γ with colon cancer cells in the tumor microenvironment., PMID:39030523
Peripheral Blood CD8+ T-Lymphocyte Immune Response in Benign and Subpopulations of Breast Cancer Patients., PMID:38928129
Cytotoxic CD4+ T Cells Are Induced during Infection with Chlamydia trachomatis., PMID:38905023
A new integrative analysis of histopathology and single cell RNA-seq reveals the CCL5 mediated T and NK cell interaction with vascular cells in idiopathic pulmonary arterial hypertension., PMID:38797830
Selective Detection of Active Extracellular Granzyme A by Using a Novel Fluorescent Immunoprobe with Application to Inflammatory Diseases., PMID:38751645
Identification of potential therapeutic targets for plaque vulnerability based on an integrated analysis., PMID:38749785
The presence of cytotoxic CD4 and exhausted-like CD8+ T-cells is a signature of active tuberculosis., PMID:38734321
Single-cell sequencing of tumour infiltrating T cells efficiently identifies tumour-specific T cell receptors based on the T cell activation score., PMID:38727812
Apolipoprotein E is a prognostic factor for pancreatic cancer and associates with immune infiltration., PMID:38704962
Tumor and Peritoneum-Associated Macrophage Gene Signature as a Novel Molecular Biomarker in Gastric Cancer., PMID:38612926
Differentially Expressed Genes Involved in Primary Resistance to Immunotherapy in Patients with Advanced-Stage Pulmonary Cancer., PMID:38396726
Single-cell RNA sequencing reveals the dynamics and heterogeneity of lymph node immune cells during acute and chronic viral infections., PMID:38352870
Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition., PMID:38307835
NK-derived exosome miR-1249-3p inhibits Mycobacterium tuberculosis survival in macrophages by targeting SKOR1., PMID:38159468
For research use only. Not for human or drug use.
