Catalog No.
RHJ32301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IF: 1:50-1:200, IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
RC3, Neurogranin, Ng, NRGN
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92686
Applications
IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2J41
Neurogranin facilitates maintaining the immunosuppressive state of hepatocellular carcinoma by promoting TGF-β1 secretion., PMID:40316076
Transcriptomic profiling of severe and critical COVID-19 patients reveals alterations in expression, splicing and polyadenylation., PMID:40251257
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds., PMID:39668376
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's Disease and related dementia research., PMID:38947090
CSF protein ratios with enhanced potential to reflect Alzheimer's disease pathology and neurodegeneration., PMID:38350954
Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer's disease: novel methodology and clinical proof of concept., PMID:37842184
Growth Hormone-Releasing Hormone Modulation of Neuronal Exosome Biomarkers in Mild Cognitive Impairment., PMID:30372675
CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease., PMID:27604409
Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile., PMID:27408937
Serum neurogranin measurement as a biomarker of acute traumatic brain injury., PMID:26025774
Transitory and activity-dependent expression of neurogranin in olfactory bulb tufted cells during mouse postnatal development., PMID:22592880
Neurogranin is expressed by principal cells but not interneurons in the rodent and monkey neocortex and hippocampus., PMID:15389613
Regulation of vascular L-type Ca2+ channels by phosphatidylinositol 3,4,5-trisphosphate., PMID:15242973
The human RC3 gene homolog, NRGN contains a thyroid hormone-responsive element located in the first intron., PMID:9886843
Nitric oxide modification of rat brain neurogranin affects its phosphorylation by protein kinase C and affinity for calmodulin., PMID:8798403
Neurogranin is locally concentrated in rat cortical and hippocampal neurons., PMID:8891262
Neurogranin in the development of the rat telencephalon., PMID:8783271
Sleep deprivation differentially alters the mRNA and protein levels of neurogranin in rat brain., PMID:7583240
Antibodies to postsynaptic PKC substrate neurogranin prevent long-term potentiation in hippocampal CA1 neurons., PMID:7620629
Regulation of p68 RNA helicase by calmodulin and protein kinase C., PMID:7525583
Monoclonal antibody NM2 recognizes the protein kinase C phosphorylation site in B-50 (GAP-43) and in neurogranin (BICKS)., PMID:8113810
Rapid purification, site-directed mutagenesis, and initial characterization of recombinant RC3/neurogranin., PMID:7654517
Thyroid hormone regulation of RC3, a brain-specific gene encoding a protein kinase-C substrate., PMID:8344193
Neurogranin: immunocytochemical localization of a brain-specific protein kinase C substrate., PMID:2269883
For research use only. Not for human or drug use.
