Catalog No.
RHJ29201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Target
HDAC7A, HD7, HD7a, Histone deacetylase 7, HDAC7, Histone deacetylase 7A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8WUI4
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2J30
Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis., PMID:39806423
Brief research report: WGCNA-driven identification of histone modification genes as potential biomarkers in AQP4-Associated optic neuritis., PMID:39238786
Construction of a molecular inflammatory predictive model with histone modification-related genes and identification of CAMK2D as a potential response signature to infliximab in ulcerative colitis., PMID:38274809
Expression of histone deacetylase (HDAC) family members in bortezomib-refractory multiple myeloma and modulation by panobinostat., PMID:34888496
MiR-342-3p inhibits LCSC oncogenicity and cell stemness through HDAC7/PTEN axis., PMID:34842937
Correction: HDAC7 is an actionable driver of therapeutic antibody resistance by macrophages from CLL patients., PMID:33353962
HDAC7 is an actionable driver of therapeutic antibody resistance by macrophages from CLL patients., PMID:32709923
CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma., PMID:32589729
Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation., PMID:29367434
Molecular and Functional Characterization of Histone Deacetylase 4 (HDAC4)., PMID:27246207
The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro., PMID:26403201
Further characterization of HDAC and SIRT gene expression patterns in pancreatic cancer and their relation to disease outcome., PMID:25275504
Quantitative phosphoproteomics of cytotoxic T cells to reveal protein kinase d 2 regulated networks., PMID:25266776
PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7., PMID:23955003
Aberrant expression pattern of histone acetylation modifiers and mitigation of lupus by SIRT1-siRNA in MRL/lpr mice., PMID:19922023
Resistance of Foxp3+ regulatory T cells to Nur77-induced apoptosis promotes allograft survival., PMID:18509529
High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas., PMID:18506539
HDAC2 controls IgM H- and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions., PMID:17352740
HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage., PMID:17038545
CRM1 mediates nuclear export of HDAC7 independently of HDAC7 phosphorylation and association with 14-3-3s., PMID:16956611
Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes., PMID:16449666
Signal Transduction and Transcription Factor Modification during Reactivation of Epstein-Barr Virus from Latency., PMID:12239305