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Anti-HDAC7 Antibody (R2J30)

Catalog #:   RHJ29201 Specific References (22) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: FCM, IF, WB
Accession: Q8WUI4
Overview

Catalog No.

RHJ29201

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000

Target

HDAC7A, HD7, HD7a, Histone deacetylase 7, HDAC7, Histone deacetylase 7A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8WUI4

Applications

FCM, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2J30

Data Image
  • Western blot
    All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
  • Western blot
    Western blot analysis of HDAC7 expression in HeLa cell lysate.
References

Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis., PMID:39806423

Brief research report: WGCNA-driven identification of histone modification genes as potential biomarkers in AQP4-Associated optic neuritis., PMID:39238786

Construction of a molecular inflammatory predictive model with histone modification-related genes and identification of CAMK2D as a potential response signature to infliximab in ulcerative colitis., PMID:38274809

Expression of histone deacetylase (HDAC) family members in bortezomib-refractory multiple myeloma and modulation by panobinostat., PMID:34888496

MiR-342-3p inhibits LCSC oncogenicity and cell stemness through HDAC7/PTEN axis., PMID:34842937

Correction: HDAC7 is an actionable driver of therapeutic antibody resistance by macrophages from CLL patients., PMID:33353962

HDAC7 is an actionable driver of therapeutic antibody resistance by macrophages from CLL patients., PMID:32709923

CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma., PMID:32589729

Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation., PMID:29367434

Molecular and Functional Characterization of Histone Deacetylase 4 (HDAC4)., PMID:27246207

The MEF2-HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro., PMID:26403201

Further characterization of HDAC and SIRT gene expression patterns in pancreatic cancer and their relation to disease outcome., PMID:25275504

Quantitative phosphoproteomics of cytotoxic T cells to reveal protein kinase d 2 regulated networks., PMID:25266776

PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7., PMID:23955003

Aberrant expression pattern of histone acetylation modifiers and mitigation of lupus by SIRT1-siRNA in MRL/lpr mice., PMID:19922023

Resistance of Foxp3+ regulatory T cells to Nur77-induced apoptosis promotes allograft survival., PMID:18509529

High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas., PMID:18506539

HDAC2 controls IgM H- and L-chain gene expressions via EBF1, Pax5, Ikaros, Aiolos and E2A gene expressions., PMID:17352740

HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage., PMID:17038545

CRM1 mediates nuclear export of HDAC7 independently of HDAC7 phosphorylation and association with 14-3-3s., PMID:16956611

Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes., PMID:16449666

Signal Transduction and Transcription Factor Modification during Reactivation of Epstein-Barr Virus from Latency., PMID:12239305

Datasheet

Document Download

Anti-HDAC7 Antibody (R2J30).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-HDAC7 Antibody (R2J30) [RHJ29201]
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