Catalog No.
YHC93501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln34-Asn316
Predicted molecular weight
33.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12318
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fc-gamma RII-a, IgG Fc receptor II-a, IGFR2, FCG2, CDw32, FCGR2A1, FCGR2A, FcRII-a, CD32, Low affinity immunoglobulin gamma Fc region receptor II-a, Fc-gamma-RIIa
A proteogenomic tool uncovers protein markers for human microglial states., PMID:40236015
( +)-Catechin Alleviates CCI-Induced Neuropathic Pain by Modulating Microglia M1 and M2 Polarization via the TLR4/MyD88/NF-κB Signaling Pathway., PMID:40195186
FcγRIIB (CD32B) antibodies enhance immune responses through activating FcγRs., PMID:40089806
Antibody-Dependent Cellular Cytotoxicity of iPS Cell-Derived Natural Killer T Cells by Anti-GD2 mAb for Neuroblastoma., PMID:39916425
Tinosinenside A inhibits neuroinflammation and protects HT22 cells by suppressing the TLR4/NF-κB/NLRP3 signaling pathway in BV2 cells., PMID:39878812
Engineered Immunomodulatory Extracellular Vesicles from Epithelial Cells with the Capacity for Stimulation of Innate and Adaptive Immunity in Cancer and Autoimmunity., PMID:39869047
Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro., PMID:39795170
C-reactive protein promotes diabetic kidney disease via Smad3-mediated NLRP3 inflammasome activation., PMID:39539016
Autoreactive B cells remain active despite clinical disease control in rheumatoid arthritis., PMID:39342827
Systematic analysis of Fc mutations designed to enhance binding to Fc-gamma receptors., PMID:39306747
Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors., PMID:39279104
Identification of a New and Effective Marker Combination for a Standardized and Automated Bin-Based Basophil Activation Test (BAT) Analysis., PMID:39272743
Fasudil attenuates syncytin-1-mediated activation of microglia and impairments of motor neurons and motor function in mice., PMID:39234934
Site-Specific Glycosylation Analysis of Human and Murine Fcγ Receptor II Family Members Reveals Variant-Specific N-Glycosylation., PMID:39007905
Bacillus amyloliquefaciens Protect Against Atherosclerosis Through Alleviating Foam Cell Formation and Macrophage Polarization., PMID:38997545
The cGAS/STING signaling pathway is involved in sevoflurane induced neuronal necroptosis via regulating microglia M1 polarization., PMID:38688381
CD32 captures committed haemogenic endothelial cells during human embryonic development., PMID:38594587
IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma., PMID:38585888
Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells., PMID:38579727
CD32 (FcγRIIB) expression is low on CD21low B cells from systemic sclerosis patients with digital ulcers, interstitial lung disease, and anti-topoisomerase I autoantibodies., PMID:38494058
Upstream Stimulating Factor 2 Aggravates Spinal Nerve Ligation-Induced Neuropathic Pain in Mice via Regulating SNHG5/miR-181b-5p., PMID:38471480
Control of complement-induced inflammatory responses to SARS-CoV-2 infection by anti-SARS-CoV-2 antibodies., PMID:38418557
Non-coding RNA LINC01010 regulates macrophage polarization and innate immune functions by modulating NFκB signaling pathway., PMID:38403999
Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis., PMID:38391367
Circadian Variation of Immune Cell Populations in Preterm Human Milk: A Preliminary Study., PMID:38386993
Fc receptors are key discriminatory markers of granulocytes subsets in people living with HIV-1., PMID:38384451
Type 2-polarized memory B cells hold allergen-specific IgE memory., PMID:38324637
Anti-Vα24Jα18 TCR Antibody Tunes iNKT Cell Responses to Target and Kill CD1d-negative Tumors in an FcγRII (CD32)-dependent Manner., PMID:38319156
Immune characteristics and clinical significance of peripheral blood lymphocytes in breast cancer., PMID:38195475
TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage., PMID:38180747
Fc-gamma receptor expression and cytokine responses to intravenous human immunoglobulin in whole blood from non-pregnant and pregnant women and newborns., PMID:38180331
Microglial histone deacetylase 2 is dispensable for functional and histological outcomes in a mouse model of traumatic brain injury., PMID:38069842
Switching Rat Resident Macrophages from M1 to M2 Phenotype by Iba1 Silencing Has Analgesic Effects in SNL-Induced Neuropathic Pain., PMID:37958812
The Role of Human Endogenous Retrovirus (HERV)-K119 env in THP-1 Monocytic Cell Differentiation., PMID:37958549
Nasal polyp antibody-secreting cells display proliferation signature in aspirin-exacerbated respiratory disease., PMID:37898408
Proteopathy Linked to Exon-Skipping Isoform of RGR-Opsin Contributes to the Pathogenesis of Age-Related Macular Degeneration., PMID:37883094
Stigmasterol regulates microglial M1/M2 polarization via the TLR4/NF-κB pathway to alleviate neuropathic pain., PMID:37871970
High levels of PD-L1 on platelets of NSCLC patients contributes to the pharmacological activity of Atezolizumab., PMID:37857253
Exploration of the mechanism of reinfusion of fresh autologous blood in type 2 diabetes mice to induce macrophage polarization and inhibit erythrocyte damage., PMID:37846170
Regulation of oxygen-glucose deprivation/reperfusion-induced inflammatory responses and M1-M2 phenotype switch of BV2 microglia by lobetyolin., PMID:37837601
Developmental adaptations of γδ T cells and B cells in blood and intestinal mucosa from birth until weaning in Holstein bull calves., PMID:37806632
Function-structure approach reveals novel insights on the interplay of Immunoglobulin G 1 proteoforms and Fc gamma receptor IIa allotypes., PMID:37790943
OMIP-097: High-parameter phenotyping of human platelets by spectral flow cytometry., PMID:37786346
Jasminoidin reduces ischemic stroke injury by regulating microglia polarization via PASK-EEF1A1 axis., PMID:37743322
[Effects of electro-scalp acupuncture on inflammatory response and microglial polarization in the ischemic cortex of rats with ischemic stroke]., PMID:37697881
DENV-specific IgA contributes protective and non-pathologic function during antibody-dependent enhancement of DENV infection., PMID:37639455
Proteomic Analysis of Dysfunctional Liver Sinusoidal Endothelial Cells Reveals Substantial Differences in Most Common Experimental Models of Chronic Liver Diseases., PMID:37569282
Activation of GABA receptor attenuates intestinal inflammation by modulating enteric glial cells function through inhibiting NF-κB pathway., PMID:37527767
The role of Kupffer cell activation in immune liver damage induced by trichloroethylene associated with the IFN-γ/STAT1 signaling pathway., PMID:37449946
Oxygen-glucose deprivation-induced glial cell reactivity in the rat primary neuron-glia co-culture., PMID:37407448
For research use only. Not for human or drug use.
