Catalog No.
YHC93301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro2-Lys381
Predicted molecular weight
44.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12277
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Creatine phosphokinase B-type, Creatine kinase B-type, CKBB, CPK-B, Brain creatine kinase, Creatine kinase B chain, B-CK, CKB
Impact of pharmacist-physician collaborative care on hemoglobin A1c and blood pressure quality measure achievement in primary care., PMID:40443003
Creation of Genetically Modified Adipocytes for Tissue Engineering: Creatine Kinase B Overexpression Leads to Stimulated Glucose Uptake and Mitochondrial Potential Growth, but Lowered Lipid Synthesis., PMID:40430181
Investigation of the protective mechanisms of liquid nitrogen spray freezing and TGase cross-linking on the structural characteristics of surimi gels during frozen storage., PMID:40267675
Celastrol targets CKB-mediated futile creatine cycle in human brown adipocytes thermogenesis., PMID:40213647
The Futile Creatine Cycle powers UCP1-independent thermogenesis in classical BAT., PMID:40185737
LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2., PMID:40066518
Dechloromonas aquae sp. nov., A Novel Species Isolated from Aquaculture Water of Grass Carp., PMID:40063307
Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m6A-dependent manner., PMID:39910429
Effect of gestational age and fetal sex on metabolism of creatine by uteri, placentae, and fetuses of pigs†., PMID:39836382
Non-Canonical TERT Activity Initiates Osteogenesis in Calcific Aortic Valve Disease., PMID:39835393
Modulatory roles of capsaicin on thermogenesis in C2C12 myoblasts and the skeletal muscle of mice., PMID:39800145
Epigenetic suppression of creatine kinase B in adipocytes links endoplasmic reticulum stress to obesity-associated inflammation., PMID:39675471
Risk prediction of ischemic heart disease using plasma proteomics, conventional risk factors and polygenic scores in Chinese and European adults., PMID:39578299
Exploring α-synuclein Interaction Partners and their Potential Clinical Implications for Parkinson's Disease., PMID:39560845
Plasma proteomic profiles reveal proteins and three characteristic patterns associated with osteoporosis: A prospective cohort study., PMID:39490735
A Comparison of White and Yellow Seminal Plasma Phosphoproteomes Obtained from Turkey (Meleagris gallopavo) Semen., PMID:39337428
Mechanistic insights into a heterobifunctional degrader-induced PTPN2/N1 complex., PMID:39152201
Endoplasmic reticulum unfolded protein response transcriptional targets of XBP-1s mediate rescue from tauopathy., PMID:39060347
Effect of 48 Months of Closed-Loop Insulin Delivery on Residual C-Peptide Secretion and Glycemic Control in Newly Diagnosed Youth With Type 1 Diabetes: A Randomized Trial., PMID:38924772
CKB Promotes Mitochondrial ATP Production by Suppressing Permeability Transition Pore., PMID:38896801
[Distribution and influencing factors of lipoprotein (a) levels in non-arteriosclerotic cardiovascular disease population in China]., PMID:38889976
Characterization of reduced astrocyte creatine kinase levels in Alzheimer's disease., PMID:38856187
Evidence for metabolism of creatine by the conceptus, placenta, and uterus for production of adenosine triphosphate during conceptus development in pigs†., PMID:38836439
[Effects of plumbagin on proliferation and apoptosis of human hepatocellular carcinoma cells based on CKB/p53 signaling pathway]., PMID:38812135
20(S)-Protopanaxadiol Exerts Antidepressive Effects in Chronic Corticosterone-Induced Rodent Animal Models as an Activator of Brain-Type Creatine Kinase., PMID:38661058
Proteomic Analyses in Diverse Populations Improved Risk Prediction and Identified New Drug Targets for Type 2 Diabetes., PMID:38623619
Capsaicin induces ATP-dependent thermogenesis via the activation of TRPV1/β3-AR/α1-AR in 3T3-L1 adipocytes and mouse model., PMID:38531438
Deficiency of polypeptide N-acetylgalactosamine transferase 9 contributes to a risk for Parkinson's disease via mitochondrial dysfunctions., PMID:38401583
RNA-binding protein IGF2BP2 suppresses metastasis of clear cell renal cell carcinoma by enhancing CKB mRNA stability and expression., PMID:38341962
Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB., PMID:38272036
Alzheimer's Disease and Aging Association: Identification and Validation of Related Genes., PMID:38230733
Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications., PMID:38101572
Plasma Proteomics to Identify Drug Targets for Ischemic Heart Disease., PMID:37940228
MTHFR and risk of stroke and heart disease in a low-folate population: a prospective study of 156 000 Chinese adults., PMID:37898918
The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity., PMID:37794185
Conventional and genetic associations of adiposity with 1463 proteins in relatively lean Chinese adults., PMID:37676424
DnaJA2 interacts with Japanese encephalitis virus NS3 via its C-terminal to promote viral infection., PMID:37633595
Phospho-DIGE Identified Phosphoproteins Involved in Pathways Related to Tumour Growth in Endometrial Cancer., PMID:37569364
Identification and analysis of cellular senescence-associated signatures in diabetic kidney disease by integrated bioinformatics analysis and machine learning., PMID:37396184
Bmal1 downregulation leads to diabetic cardiomyopathy by promoting Bcl2/IP3R-mediated mitochondrial Ca2+ overload., PMID:37356134
Protracted morphine withdrawal induces upregulation of peroxiredoxin II and reduces 14-3-3 protein levels in the rat brain cortex and hippocampus., PMID:37263551
Role of creatine shuttle in colorectal cancer cells., PMID:37204253
Creatine kinase brain-type regulates BCAR1 phosphorylation to facilitate DNA damage repair., PMID:37182100
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function., PMID:37156912
Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa., PMID:37101650
Investigation of the dual role of acyl phloroglucinols as a new hope for antibacterial and anti-SARS-CoV-2 agents employing integrated in vitro and multi-phase in silico approaches., PMID:36927239
Proteomic and bioinformatic analysis of human endometrium from polycystic ovarian syndrome with and without insulin resistance., PMID:36750132
Implanted Tissue-Engineered Vascular Graft Cell Isolation with Single-Cell RNA Sequencing Analysis., PMID:36719780
Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradation., PMID:36683111
Fully automated closed-loop insulin delivery in adults with type 2 diabetes: an open-label, single-center, randomized crossover trial., PMID:36631592
For research use only. Not for human or drug use.
