Catalog No.
RHH20101
Species reactivity
Human, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Tested applications
IP: 1:20, WB: 1:500-1:1000
Target
BSP1, Mothers against DPP homolog 1, Mothers against decapentaplegic homolog 1, SMAD1, Transforming growth factor-beta-signaling protein 1, MADH1, JV4-1, MADR1, SMAD family member 1, hSMAD1, SMAD 1, MAD homolog 1, Mad-related protein 1, BSP-1, Smad1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15797
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Clone ID
R2G70
Specific Blockade of Bone Morphogenetic Protein-2/4 Induces Oligodendrogenesis and Remyelination in Demyelinating Disorders., PMID:34159538
Immunofluorescent Visualization of BMP Signaling Activation on Paraffin-Embedded Tissue Sections., PMID:30414134
Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development., PMID:24777107
Low-intensity pulsed ultrasound induces osteogenic differentiation of human periodontal ligament cells through activation of bone morphogenetic protein-smad signaling., PMID:24764342
The immunoglobulin superfamily protein differentiation of embryonic stem cells 1 (dies1) has a regulatory role in preadipocyte to adipocyte conversion., PMID:23799023
Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8., PMID:21996749
Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm., PMID:21613322
Activation of Src mediates PDGF-induced Smad1 phosphorylation and contributes to the progression of glomerulosclerosis in glomerulonephritis., PMID:21445358
Detection of signaling effector-complexes downstream of bmp4 using PLA, a proximity ligation assay., PMID:21403637
A sensitive detection of phospho-Smad1/5/8 and Smad2 in Western blot analyses., PMID:17976733
Functional role of bone morphogenetic protein-4 in isolated canine parietal cells., PMID:17600042
Cyclooxygenase-2 expression in polyps from a patient with juvenile polyposis syndrome with mutant BMPR1A., PMID:17325551
The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells., PMID:16818503
A novel vitamin D derivative activates bone morphogenetic protein signaling in MCF10 breast epithelial cells., PMID:16533909
Activation of STAT3/Smad1 is a key signaling pathway for progression to glomerulosclerosis in experimental glomerulonephritis., PMID:15591053
BMP and activin receptor expression in lens development., PMID:15346106
Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes., PMID:12925609
Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development., PMID:10851136