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Recombinant Human CYP19A1 Protein, N-His

Catalog #:   YHC89401 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P11511
Protein length: Leu196-Val373
Overview

Catalog No.

YHC89401

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Leu196-Val373

Predicted molecular weight

23.10 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P11511

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

CYAR, Estrogen synthase, CYP19A1, CYPXIX, ARO1, Cytochrome P-450AROM, Aromatase, Cytochrome P450 19A1, CYP19

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human CYP19A1 protein
References

Apricot Bee Pollen Alleviates Deoxynivalenol-Induced Cellular Toxicity in Bovine Granulosa Cells., PMID:40509046

Combined Oral Contraceptives Modulate Apoptosis via IL-11/PI3K/AKT Pathway in Rat With Premature Ovarian Insufficiency., PMID:40485524

Propofol-mediated inhibition of ovarian function by mitophagy over-activation via TGF-β1/SMAD2/3 signaling pathway., PMID:40480431

Estrogen receptor β mediates the feedback loop between 17β-Estradiol and CYP19A1, which controls transcriptomic stability, inhibits granulosa cell apoptosis, induces oocyte maturation and influences sow fertility., PMID:40466836

Discovery of CYP1A1 Inhibitors for Host-Directed Therapy against Sepsis., PMID:40442943

AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep., PMID:40442469

Semaglutide Alleviates Ovarian Oxidative Stress and Autophagy via the PI3K/AKT/mTOR Pathway in Mice with Polycystic Ovary Syndrome., PMID:40433568

Effects of Copper on Steroid Hormone Secretion, Steroidogenic Enzyme Expression, and Transcriptomic Profiles in Yak Ovarian Granulosa Cells., PMID:40431521

Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts., PMID:40424442

Nano-sized titanium dioxide exposure induces non-hyperandrogenic polycystic ovarian syndrome in rats by increasing aromatase and apoptosis in granulosa cells., PMID:40412962

Tris(2-chloroisopropyl) phosphate (TCPP) decreases CYP1A1, CYP1A2, and CYP1B1/CYP2B expression and activities through potential interactions between AhR and NRF2 pathways in the HepG2 cell line., PMID:40412367

HNRNPA2B1-mediated m6A modification enhances lncRNA NORHA stability to control granulosa cell functions., PMID:40407136

1,25(OH)2D3 up-regulated mitochondrial dynamics and biogenesis to modulate steroidogenesis in the scent glands of muskrats (Ondatra zibethicus)., PMID:40398522

Comparison of submerged and air liquid interface exposure: limitations and differences in the toxicological effects evaluated in bronchial epithelial cells., PMID:40379004

Mechanisms involved in pro-inflammatory responses to traffic-derived particulate matter (PM) in THP-1 macrophages compared to HBEC3-KT bronchial epithelial cells., PMID:40345318

Combining ATAC-seq and RNA-seq reveals key genes for gonadal abnormalities in one-month-old XX-DSD pigs., PMID:40329180

Polycyclic aromatic hydrocarbon-aryl hydrocarbon receptor signaling regulates chronic inflammation in lung-gut axis., PMID:40320014

Sex Differences in Colonic Inflammation are Driven by Epithelial-Specific Expression of Estrogen Receptor Alpha., PMID:40297530

Effects of an aryl hydrocarbon receptor ligand on human trophoblast cell development., PMID:40294436

CCAAT/Enhancer-Binding Proteins α and β Regulate Ovulation and Gene Expression via Dose- and Stage-Dependent Mechanisms., PMID:40294160

CYP1A1/1A2 enzymes mediate glucose homeostasis and insulin secretion in mice in a sex-specific manner., PMID:40293922

Roles of GDF9 and BMP15 in equine follicular development: in vivo content and in vitro effects of IGF1 and cortisol on granulosa cells., PMID:40289073

Involvement of cholesterol and ketone bodies in early stages of bovine cystic ovarian disease development., PMID:40286443

An Inducible CYP19A1 Excision Model for Sexual Differentiation in Chicken (Gallus gallus) via the CRISPR/Cas9 System., PMID:40284798

Integrated lncRNA and mRNA Transcriptome Analyses of IGF1 and IGF2 Stimulated Ovaries Reveal Genes and Pathways Potentially Associated with Ovarian Development and Oocyte Maturation in Golden Pompano (Trachinotus ovatus)., PMID:40281968

Consequences of vitamin D deficiency or overdosage on follicular development and steroidogenesis in Normo and hypo calcemic mouse models., PMID:40274992

Regulating human oocyte maturation in vitro: a hypothesis based on oocytes retrieved from small antral follicles during ovarian tissue cryopreservation., PMID:40261459

Edaravone ameliorates inflammation in ischemic stroke mouse by regulating the CYP1A1 pathway through gut microbiota., PMID:40258529

Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates., PMID:40258480

Impact of metformin on gene expression in Burmese loach (Lepidocephalichthys berdmorei) from Manipur, India., PMID:40253858

IDO1 inhibitors block septic cytokine storm by suppressing the IDO1-AHR-CYP1A1 axis., PMID:40245547

Species differences in microsomal metabolism of hydroxychloroquine., PMID:40233867

D-chiro-inositol effectively counteracts endometriosis in a mouse model., PMID:40211112

PM2.5 exacerbates nasal epithelial barrier dysfunction in allergic rhinitis by inducing NLRP3-mediated pyroptosis via the AhR/CYP1A1/ROS axis., PMID:40209413

Changes in goose hypothalamus under different photocycles: RNA-Seq reveals new pathways and molecules., PMID:40203726

Dynamic Regulation of CYP19A1 Promoter Region under Control of CREB Family Members in Endometrial Tissues of Women with Endometriosis: A Case-Control Study., PMID:40200772

The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid., PMID:40194363

Zingerone modulates the circulating steroids hormone levels and testicular steroidogenic markers expression in mice: An in vivo and in silico study., PMID:40189108

Exploring bioactive natural products for treating neurodegenerative diseases: a computational network medicine approach targeting the estrogen signaling pathway in amyotrophic lateral sclerosis and Parkinson's disease., PMID:40184012

A novel mechanism for A-to-I RNA-edited CYP1A1 in promoting cancer progression in NSCLC., PMID:40175891

Activation of the arylhydrocarbon receptor through maternal beta-naphthoflavone exposure in the neonatal kidney., PMID:40175110

Aromatase reduces sperm motility by down-regulating the expression of proteins related to ATP synthesis in seminal plasma extracellular vesicles., PMID:40155807

Genetic Variations in CYP19A1 and SLCO1B1 Genes and Their Association with Endometrial Cancer Risk in the Taiwanese Population: A Case-Control Study., PMID:40141105

Oxidative Stress, DNA Damage, Ethoxyresorufin-O-deethylase Induction and Neurotoxicity Caused by Environmental Pollutants in Cyprinus carpio (Linnaeus, 1758) from Atatürk Dam Lake (Türkiye)., PMID:40119921

Cigarette smoking modulates m6A modification, affecting the induction of CYP1A1 mRNA by regulating human ARNT and AHRR in A549 cells., PMID:40118351

Knockdown of cytochrome P450 1 A (cyp1a) gene suppresses growth and oxygen tolerance in zebrafish., PMID:40118204

Integrated Virtual Screening Approach Identifies New CYP19A1 Inhibitors., PMID:40106333

Whole exome sequencing uncovers rare variants associated with PCOS susceptibility in Indian women., PMID:40085772

Phytochemical-Mediated Ah Receptor Activity Is Dependent on Dietary Context., PMID:40077746

The Role of Primary Cilia in Modulating the Luteinization Process of Ovarian Granulosa Cells in Mice., PMID:40076758

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human CYP19A1 Protein, N-His [YHC89401]
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