Catalog No.
YHC89401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu196-Val373
Predicted molecular weight
23.10 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11511
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CYAR, Estrogen synthase, CYP19A1, CYPXIX, ARO1, Cytochrome P-450AROM, Aromatase, Cytochrome P450 19A1, CYP19
Apricot Bee Pollen Alleviates Deoxynivalenol-Induced Cellular Toxicity in Bovine Granulosa Cells., PMID:40509046
Combined Oral Contraceptives Modulate Apoptosis via IL-11/PI3K/AKT Pathway in Rat With Premature Ovarian Insufficiency., PMID:40485524
Propofol-mediated inhibition of ovarian function by mitophagy over-activation via TGF-β1/SMAD2/3 signaling pathway., PMID:40480431
Estrogen receptor β mediates the feedback loop between 17β-Estradiol and CYP19A1, which controls transcriptomic stability, inhibits granulosa cell apoptosis, induces oocyte maturation and influences sow fertility., PMID:40466836
Discovery of CYP1A1 Inhibitors for Host-Directed Therapy against Sepsis., PMID:40442943
AMH regulates granulosa cell function via ESR2/ p38-MAPK signaling pathway in sheep., PMID:40442469
Semaglutide Alleviates Ovarian Oxidative Stress and Autophagy via the PI3K/AKT/mTOR Pathway in Mice with Polycystic Ovary Syndrome., PMID:40433568
Effects of Copper on Steroid Hormone Secretion, Steroidogenic Enzyme Expression, and Transcriptomic Profiles in Yak Ovarian Granulosa Cells., PMID:40431521
Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts., PMID:40424442
Nano-sized titanium dioxide exposure induces non-hyperandrogenic polycystic ovarian syndrome in rats by increasing aromatase and apoptosis in granulosa cells., PMID:40412962
Tris(2-chloroisopropyl) phosphate (TCPP) decreases CYP1A1, CYP1A2, and CYP1B1/CYP2B expression and activities through potential interactions between AhR and NRF2 pathways in the HepG2 cell line., PMID:40412367
HNRNPA2B1-mediated m6A modification enhances lncRNA NORHA stability to control granulosa cell functions., PMID:40407136
1,25(OH)2D3 up-regulated mitochondrial dynamics and biogenesis to modulate steroidogenesis in the scent glands of muskrats (Ondatra zibethicus)., PMID:40398522
Comparison of submerged and air liquid interface exposure: limitations and differences in the toxicological effects evaluated in bronchial epithelial cells., PMID:40379004
Mechanisms involved in pro-inflammatory responses to traffic-derived particulate matter (PM) in THP-1 macrophages compared to HBEC3-KT bronchial epithelial cells., PMID:40345318
Combining ATAC-seq and RNA-seq reveals key genes for gonadal abnormalities in one-month-old XX-DSD pigs., PMID:40329180
Polycyclic aromatic hydrocarbon-aryl hydrocarbon receptor signaling regulates chronic inflammation in lung-gut axis., PMID:40320014
Sex Differences in Colonic Inflammation are Driven by Epithelial-Specific Expression of Estrogen Receptor Alpha., PMID:40297530
Effects of an aryl hydrocarbon receptor ligand on human trophoblast cell development., PMID:40294436
CCAAT/Enhancer-Binding Proteins α and β Regulate Ovulation and Gene Expression via Dose- and Stage-Dependent Mechanisms., PMID:40294160
CYP1A1/1A2 enzymes mediate glucose homeostasis and insulin secretion in mice in a sex-specific manner., PMID:40293922
Roles of GDF9 and BMP15 in equine follicular development: in vivo content and in vitro effects of IGF1 and cortisol on granulosa cells., PMID:40289073
Involvement of cholesterol and ketone bodies in early stages of bovine cystic ovarian disease development., PMID:40286443
An Inducible CYP19A1 Excision Model for Sexual Differentiation in Chicken (Gallus gallus) via the CRISPR/Cas9 System., PMID:40284798
Integrated lncRNA and mRNA Transcriptome Analyses of IGF1 and IGF2 Stimulated Ovaries Reveal Genes and Pathways Potentially Associated with Ovarian Development and Oocyte Maturation in Golden Pompano (Trachinotus ovatus)., PMID:40281968
Consequences of vitamin D deficiency or overdosage on follicular development and steroidogenesis in Normo and hypo calcemic mouse models., PMID:40274992
Regulating human oocyte maturation in vitro: a hypothesis based on oocytes retrieved from small antral follicles during ovarian tissue cryopreservation., PMID:40261459
Edaravone ameliorates inflammation in ischemic stroke mouse by regulating the CYP1A1 pathway through gut microbiota., PMID:40258529
Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates., PMID:40258480
Impact of metformin on gene expression in Burmese loach (Lepidocephalichthys berdmorei) from Manipur, India., PMID:40253858
IDO1 inhibitors block septic cytokine storm by suppressing the IDO1-AHR-CYP1A1 axis., PMID:40245547
Species differences in microsomal metabolism of hydroxychloroquine., PMID:40233867
D-chiro-inositol effectively counteracts endometriosis in a mouse model., PMID:40211112
PM2.5 exacerbates nasal epithelial barrier dysfunction in allergic rhinitis by inducing NLRP3-mediated pyroptosis via the AhR/CYP1A1/ROS axis., PMID:40209413
Changes in goose hypothalamus under different photocycles: RNA-Seq reveals new pathways and molecules., PMID:40203726
Dynamic Regulation of CYP19A1 Promoter Region under Control of CREB Family Members in Endometrial Tissues of Women with Endometriosis: A Case-Control Study., PMID:40200772
The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid., PMID:40194363
Zingerone modulates the circulating steroids hormone levels and testicular steroidogenic markers expression in mice: An in vivo and in silico study., PMID:40189108
Exploring bioactive natural products for treating neurodegenerative diseases: a computational network medicine approach targeting the estrogen signaling pathway in amyotrophic lateral sclerosis and Parkinson's disease., PMID:40184012
A novel mechanism for A-to-I RNA-edited CYP1A1 in promoting cancer progression in NSCLC., PMID:40175891
Activation of the arylhydrocarbon receptor through maternal beta-naphthoflavone exposure in the neonatal kidney., PMID:40175110
Aromatase reduces sperm motility by down-regulating the expression of proteins related to ATP synthesis in seminal plasma extracellular vesicles., PMID:40155807
Genetic Variations in CYP19A1 and SLCO1B1 Genes and Their Association with Endometrial Cancer Risk in the Taiwanese Population: A Case-Control Study., PMID:40141105
Oxidative Stress, DNA Damage, Ethoxyresorufin-O-deethylase Induction and Neurotoxicity Caused by Environmental Pollutants in Cyprinus carpio (Linnaeus, 1758) from Atatürk Dam Lake (Türkiye)., PMID:40119921
Cigarette smoking modulates m6A modification, affecting the induction of CYP1A1 mRNA by regulating human ARNT and AHRR in A549 cells., PMID:40118351
Knockdown of cytochrome P450 1 A (cyp1a) gene suppresses growth and oxygen tolerance in zebrafish., PMID:40118204
Integrated Virtual Screening Approach Identifies New CYP19A1 Inhibitors., PMID:40106333
Whole exome sequencing uncovers rare variants associated with PCOS susceptibility in Indian women., PMID:40085772
Phytochemical-Mediated Ah Receptor Activity Is Dependent on Dietary Context., PMID:40077746
The Role of Primary Cilia in Modulating the Luteinization Process of Ovarian Granulosa Cells in Mice., PMID:40076758