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Anti-DAG1/Dystroglycan Antibody (R2F19)

Catalog #:   RHG70901 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: WB
Accession: Q14118
Overview

Catalog No.

RHG70901

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

WB: 1:500-1:1000

Target

Dystrophin-associated glycoprotein 1, DAG1, Alpha-DG, Dystroglycan, Beta-DG

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q14118

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2F19

Data Image
  • Western blot
    Western blot analysis of beta Dystroglycan in MCF-7, HepG2, Lncap lysates using beta Dystroglycan antibody.
References

Exogenous laminin exhibits a unique vascular pattern in the brain via binding to dystroglycan and integrins., PMID:36463265

Genome-Wide Knockout Screen Identifies Human Sialomucin CD164 as an Essential Entry Factor for Lymphocytic Choriomeningitis Virus., PMID:35502904

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338

Novel Insight in Idiopathic Normal Pressure Hydrocephalus (iNPH) Biomarker Discovery in CSF., PMID:34360799

M. leprae interacts with the human epidermal keratinocytes, neonatal (HEKn) via the binding of laminin-5 with α-dystroglycan, integrin-β1, or -β4., PMID:31233498

Immunohistochemistry of sarcolemmal membrane-associated proteins in formalin-fixed and paraffin-embedded skeletal muscle tissue: a promising tool for the diagnostic evaluation of common muscular dystrophies., PMID:28219397

Structural analysis of galactoarabinan from duckweed., PMID:25498703

Development of rabbit monoclonal antibodies for detection of alpha-dystroglycan in normal and dystrophic tissue., PMID:24824861

Correlation of deregulated like-acetylglucosaminyl transferase and aberrant α-dystroglycan expression with human tongue cancer metastasis., PMID:24629698

Knockdown of col22a1 gene in zebrafish induces a muscular dystrophy by disruption of the myotendinous junction., PMID:24131632

Elevated serum creatine kinase and small cerebellum prompt diagnosis of congenital muscular dystrophy due to FKRP mutations., PMID:23420653

Direct identification of ligand-receptor interactions on living cells and tissues., PMID:22983091

Secretion of N-terminal domain of α-dystroglycan in cerebrospinal fluid., PMID:21741360

Reduced glycosylation of α-dystroglycans on carcinoma cells contributes to formation of highly infiltrative histological patterns in prostate cancer., PMID:21656825

Reduced α-dystroglycan expression correlates with shortened patient survival in pancreatic cancer., PMID:20338590

Muscular dystrophy associated with alpha-dystroglycan deficiency in Sphynx and Devon Rex cats., PMID:18990577

Aberrant expression of alpha-dystroglycan in cervical and vulvar cancer., PMID:16765426

Proteolysis of beta-dystroglycan in muscular diseases., PMID:15833425

Electron microscopy of an alpha-dystroglycan fragment containing receptor sites for lymphocytic choriomeningitis virus and laminin, and use of the receptoid body as a reagent to neutralize virus., PMID:15246261

POMT1 mutation results in defective glycosylation and loss of laminin-binding activity in alpha-DG., PMID:15037715

Hypoglycosylation of alpha-dystroglycan in patients with hereditary IBM due to GNE mutations., PMID:14972325

Mutations in the human LARGE gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan., PMID:12966029

Opposing roles of integrin alpha6Abeta1 and dystroglycan in laminin-mediated extracellular signal-regulated kinase activation., PMID:12802077

Localization of phospho-beta-dystroglycan (pY892) to an intracellular vesicular compartment in cultured cells and skeletal muscle fibers in vivo., PMID:12795607

[Sarcoglycanopathies, a particular limb-girdle muscular dystrophy type (phenotype in three Polish families): initial report]., PMID:12715687

Dystroglycan expression in the mouse cochlea., PMID:12618313

Dystrophin isoform Dp7l is present in lamellipodia and focal complexes in human astrocytoma cells U-373 MG., PMID:12389738

Dystroglycan expression in hepatic stellate cells: role in liver fibrosis., PMID:12177244

Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 nef in cells of the immune system., PMID:12107117

Defective assembly of sarcoglycan complex in patients with beta-sarcoglycan gene mutations. Study of aneural and innervated cultured myotubes., PMID:12060343

Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo., PMID:11884516

A neuronal inhibitory domain in the N-terminal half of agrin., PMID:11793362

Localization of sarcoglycan, neuronal nitric oxide synthase, beta-dystroglycan, and dystrophin molecules in normal skeletal myofiber: triple immunogold labeling electron microscopy., PMID:11747090

Reduced expression of dystroglycan in breast and prostate cancer., PMID:11521221

Mutant glycosyltransferase and altered glycosylation of alpha-dystroglycan in the myodystrophy mouse., PMID:11381262

Airway epithelial cell wound repair mediated by alpha-dystroglycan., PMID:11159052

Structural and functional analysis of the recombinant G domain of the laminin alpha4 chain and its proteolytic processing in tissues., PMID:10934193

Distinct patterns of dystrophin organization in myocyte sarcolemma and transverse tubules of normal and diseased human myocardium., PMID:10840009

Association of nonsense mutation of dystrophin gene with disruption of sarcoglycan complex in X-linked dilated cardiomyopathy., PMID:10832829

Adhesion-dependent tyrosine phosphorylation of (beta)-dystroglycan regulates its interaction with utrophin., PMID:10769203

Noval mutation (Y184C) in exon 4 of the beta-sarcoglycan gene identified in a Portuguese patient. Mutations in brief no. 177. Online., PMID:10660328

Mutation of a basic sequence in the laminin alpha2LG3 module leads to a lack of proteolytic processing and has different effects on beta1 integrin-mediated cell adhesion and alpha-dystroglycan binding., PMID:10570932

Differential distribution of dystrophin and beta-spectrin at the sarcolemma of fast twitch skeletal muscle fibers., PMID:10531619

Loss of the sarcoglycan complex and sarcospan leads to muscular dystrophy in beta-sarcoglycan-deficient mice., PMID:10441321

Decreased expression of laminin beta 1 in chromosome 21-linked Bethlem myopathy., PMID:10407855

Secondary reduction of alpha7B integrin in laminin alpha2 deficient congenital muscular dystrophy supports an additional transmembrane link in skeletal muscle., PMID:10371075

Quantitative analysis of immunofluorescent signals for dystrophin, beta-dystroglycan and myosin skeletal muscle by epifluorescence microscopy., PMID:10333406

Multiplex Western blotting system for the analysis of muscular dystrophy proteins., PMID:10233840

Ultrastructural localization of alpha-, beta- and gamma-sarcoglycan and their mutual relation, and their relation to dystrophin, beta-dystroglycan and beta-spectrin in normal skeletal myofiber., PMID:10090677

Identification of laminin-10/11 as a strong cell adhesive complex for a normal and a malignant human epithelial cell line., PMID:9841899

Datasheet
$ 290
Product specifications
50 μg 290 100 μg 484

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For research use only. Not for human or drug use.

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Anti-DAG1/Dystroglycan Antibody (R2F19) [RHG70901]
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