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Anti-RUNX2 Antibody (R2F10)

Catalog #:   RHG67901 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: IF, IHC, WB
Accession: Q13950
Overview

Catalog No.

RHG67901

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Monoclonal

Tested applications

IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000

Target

AML3, OSF2, RUNX2, Core-binding factor subunit alpha-1, PEA2-alpha A, CBF-alpha-1, Osteoblast-specific transcription factor 2, Oncogene AML-3, CBFA1, Runt-related transcription factor 2, PEBP2A, OSF-2, SL3-3 enhancer factor 1 alpha A subunit, PEBP2-alpha A, Acute myeloid leukemia 3 protein, Polyomavirus enhancer-binding protein 2 alpha A subunit, SL3/AKV core-binding factor alpha A subunit

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13950

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Clone ID

R2F10

Data Image
  • Immunofluorescence
    Immunofluorescent analysis of Saos-2 cells, using RUNX2 Antibody.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human colon, using RUNX2 Antibody.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
  • Western blot
    All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
References

Experimental investigation of the effects of allantoin on mandibular distraction osteogenesis., PMID:40461339

TSAb inhibits osteogenic differentiation of MC3T3-E1 cells and exacerbates bone loss in Graves' disease mice., PMID:40354515

Adipose-Derived Mesenchymal Stem Cell Osteodifferentiation after Exposure to Beta-Tricalcium Phosphate Bioceramic Granules with 300 to 600 and 600 to 1,000 µm Sizes., PMID:40334681

Comparison of the bone remodeling in the midpalatal suture during maxillary expansion between young and middle-aged mice., PMID:40324615

Multi-lineage transcriptional and cell communication signatures define pathways in individuals at-risk for developing rheumatoid arthritis that initiate and perpetuate disease., PMID:40235495

Influence of surface texture on osteogenic differentiation of dental pulp stem cells: An in vitro study., PMID:40018713

Multi-lineage transcriptional and cell communication signatures define pathways in individuals at-risk for developing rheumatoid arthritis that initiate and perpetuate disease., PMID:39974976

Alterations of bone proteins in medication-related osteonecrosis of the jaw., PMID:39972547

Dental Pulp Stem Cell Conditioned Medium Enhance Osteoblastic Differentiation and Bone Regeneration., PMID:39514179

Reversal of heavy arterial calcification in a rat model of chronic kidney disease using targeted ethylene diamine tetraacetic acid-loaded albumin nanoparticles., PMID:39263487

Selective inhibition of interleukin 6 receptor decreased inflammatory cytokines and increased proteases in an experimental model of critical calvarial defect., PMID:39166608

Bioactive nanocomposite hydrogel enhances postoperative immunotherapy and bone reconstruction for osteosarcoma treatment., PMID:39079462

Nanoquantification of RUNX2 by a 1,1'-carbonyldiimidazole-diamond mediated sandwich assay for osteogenic differentiation., PMID:38868000

Remote Activation of Mechanotransduction via Integrin Alpha-5 via Aptamer-Conjugated Magnetic Nanoparticles Promotes Osteogenesis., PMID:38258032

A modified animal-free serum technique for efficient isolation and proliferation of mesenchymal stem cells from Hoffa fat pad., PMID:38158693

DLL4/Notch blockade disrupts mandibular advancement-induced condylar osteogenesis by inhibiting H-type angiogenesis., PMID:38100236

Carbonate apatite increases gene expression of osterix and bone morphogenetic protein 2 in the alveolar ridge after socket grafting., PMID:38008425

1,25-Dihydroxyvitamin D3: A Positive Factor for the Osteogenic Differentiation of hPDLSCs and for the Tissue Regenerative Activity of Cell Sheets., PMID:37798942

Atp6i deficient mouse model uncovers transforming growth factor-β1 /Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation., PMID:37599332

Investigation of osteogenesis and angiogenesis in perfusion bioreactors using improved multi-layer PCL-nHA-nZnO electrospun scaffolds., PMID:37439932

IL-17A induces valvular endothelial inflammation and aggravates calcific aortic valve disease., PMID:37354607

Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA., PMID:37340499

Epigenomic landscape exhibits interferon signaling suppression in the patient of myocarditis after BNT162b2 vaccination., PMID:37264110

The calcium channel Orai1 is required for osteoblast development: Studies in a chimeric mouse with variable in vivo Runx-cre deletion of Orai-1., PMID:37167218

Histochemical assessment of osteoclast-like giant cells in Rankl-/- mice., PMID:37088151

Biological activity of a chitosan-carboxymethylcellulose-zinc oxide and calcium carbonate in 3D scaffolds stabilized by physical links for bone tissue engineering., PMID:37025081

[The role of semaphorin 4D in the mechanism of bisphosphonate-related osteonecrosis of the jaw in rats]., PMID:36970799

Indoxyl-sulfate activation of the AhR- NF-κB pathway promotes interleukin-6 secretion and the subsequent osteogenic differentiation of human valvular interstitial cells from the aortic valve., PMID:36967106

OP3-4 peptide sustained-release hydrogel inhibits osteoclast formation and promotes vascularization to promote bone regeneration in a rat femoral defect model., PMID:36925715

Effects of Dlx2 overexpression on the genes associated with the maxillary process in the early mouse embryo., PMID:36891149

Prostate cancer cell‑derived spondin 2 boosts osteogenic factor levels in osteoblasts via the PI3K/AKT/mTOR pathway., PMID:36484410

Nogo-A Regulates the Fate of Human Dental Pulp Stem Cells toward Osteogenic, Adipogenic, and Neurogenic Differentiation., PMID:36359811

Sclerostin ablation prevents aortic valve stenosis in mice., PMID:36240434

Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling., PMID:36198906

microRNA Expression Profile of Purified Alveolar Epithelial Type II Cells., PMID:36011331

Mechanical Stretch Induced Osteogenesis on Human Annulus Fibrosus Cells through Upregulation of BMP-2/6 Heterodimer and Activation of P38 and SMAD1/5/8 Signaling Pathways., PMID:36010676

HOXC10 intronic duplication is associated with unsealed skull and crest in crested chicken with cerebral hernia., PMID:35905851

Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF/RUNX2/OSX signaling axis., PMID:35795995

Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification., PMID:35795373

Abaloparatide Improves Rotator Cuff Healing via Anabolic Effects on Bone Remodeling in a Chronic Rotator Cuff Tear Model of Rat With Osteoporosis: A Comparison With Denosumab., PMID:35404150

Pathological differences in the bone healing processes between tooth extraction socket and femoral fracture., PMID:35372643

Improvement of Lipotoxicity-Induced Islet β Cellular Insulin Secretion Disorder by Osteocalcin., PMID:35313683

The use of alkaline phosphatase and runx2 to distinguish osteosarcoma from other common malignant primary bone tumors in dogs., PMID:35253545

Precision-engineered niche for directed differentiation of MSCs to lineage-restricted mineralized tissues., PMID:35237403

p53 deficiency promotes bone regeneration by functional regulation of mesenchymal stromal cells and osteoblasts., PMID:35195777

KLF4, negatively regulated by miR-7, suppresses osteoarthritis development via activating TGF-β1 signaling., PMID:34891002

Migratory chondroprogenitors retain superior intrinsic chondrogenic potential for regenerative cartilage repair as compared to human fibronectin derived chondroprogenitors., PMID:34880351

Interleukin-1 Is Overexpressed in Injured Muscles Following Spinal Cord Injury and Promotes Neurogenic Heterotopic Ossification., PMID:34841579

Local Renin-Angiotensin System Signaling Mediates Cellular Function of Aortic Valves., PMID:34704164

Identification of GPC3 mutation and upregulation in a multidrug resistant osteosarcoma and its spheroids as therapeutic target., PMID:34611509

Datasheet

Document Download

Anti-RUNX2 Antibody (R2F10).pdf

 

$ 290
Product specifications
50 μg 290 100 μg 484

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Anti-RUNX2 Antibody (R2F10) [RHG67901]
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